RF power design optimization in MRI system
August 2021
Magnetic resonance image quality and patient safety have been the focus of engineering and research ever since the invention of equipment in the early 1970s. In high field (or ultrahigh field) MRI systems,...
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Operando NMR methods for studying electrocatalysis
Available online 8 January 2024
The combination of electrochemical measurements with spectroscopic characterizations provides valuable insights into reaction mechanisms. Nuclear magnetic resonance (NMR) spectroscopy, as a powerful...
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Overview and progress of X-nuclei magnetic resonance imaging in biomedical studies
November 2023
Proton nuclear (1H) is the observed nucleus on which most magnetic resonance imaging (MRI) applications depend. Most traditional 1H MRI can provide structural and functional information about organisms,...
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Experimental aspects of 14N overtone RESPDOR solid-state NMR spectroscopy under MAS beyond 60 kHz
February 2024
Nitrogen-14 (14N) overtone (OT) spectroscopy under fast magic angle spinning (MAS) conditions (>60 kHz) has emerged as a powerful technique for observing correlations and distances between 14N and 1H,...
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Probing electronic structures of transition metal complexes using electron paramagnetic resonance spectroscopy
February 2023
Electron paramagnetic resonance (EPR) or electron spin resonance (ESR) has been widely employed to characterize transition metal complexes. However, because of the high degree of complexity of transition...
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A review of functional MRI application for brain research of Chinese language processing
February 2023
As one of the most widely used languages in the world, Chinese language is distinct from most western languages in many properties, thus providing a unique opportunity for understanding the brain basis...
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23Na relaxometry: An overview of theory and applications
May 2023
23Na is a nuclear magnetic resonance (NMR)-active isotope with a nuclear spin quantum number of 3/2. 23Na relaxation phenomenon is at the core of 23Na NMR measurement and analysis. Due to the dominance...
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Unexpected temperature dependence of 1H paramagnetic shift in MAS NMR of nickelocene
Available online 27 March 2024
This work revisits the temperature dependence of 1H paramagnetic shift in nickelocene as a potential nuclear magnetic resonance (NMR) thermometer under fast magic angle spinning (MAS) rate. Surprisingly,...
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Progress in in-situ electrochemical nuclear magnetic resonance for battery research
Available online 24 January 2024
A thorough understanding of the fundamental electrochemical and chemical processes in batteries is crucial to advancing energy density and power density. However, the characterizations of such processes...
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Rheo-NMR: A versatile hyphenated technique for capturing molecular dynamics and structure under flow
February 2024
The general development of Rheo-NMR during the last four decades as well as selective hyphenated apparatuses is presented. Based on different magnet types, the current review is divided into two categories,...
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Low-field, high-gradient NMR shows diffusion contrast consistent with localization or motional averaging of water near surfaces
May 2023
Nuclear magnetic resonance (NMR) measurements of water diffusion have been extensively used to probe microstructure in porous materials, such as biological tissue, however primarily using pulsed gradient...
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Gradient coil design with enhanced shielding constraint for a cryogen-free superconducting MRI system
February 2024
The relatively fragile low-temperature stability of cryogen-free superconducting magnetic resonance imaging (MRI) magnets requires the careful management of exogenous heat sources. A strongly shielded...
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Using NMR-detected hydrogen-deuterium exchange to quantify protein stability in cosolutes, under crowded conditions in vitro and in cells
November 2023
We review the use of nuclear magnetic resonance (NMR) spectroscopy to assess the exchange of amide protons for deuterons (HDX) in efforts to understand how high concentration of cosolutes, especially...
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Facile identification of fluorosurfactant category in aqueous film-forming foam concentrates via optimized 19F NMR
Available online 9 January 2024
Aqueous film-forming foams (AFFFs) are the primary source of toxic perfluoroalkyl and polyfluoroalkyl substances (PFAS) in wastewater. Thus, it is urgent to develop a facile and fast method for identifying...
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1H and 13C NMR spectral assignments for low-concentration bile acids in biological samples
November 2023
Bile acids are the main body of enterohepatic circulation in vivo. They have essential functions such as emulsifying fat, bacteriostasis and regulating multiple metabolic pathways as signal molecules....
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Solid-state NMR in the field of drug delivery: State of the art and new perspectives
August 2021
In the last decades, a variety of nuclear magnetic resonance (NMR) techniques have been applied with success in the field of advanced functional materials, including the important area of drug delivery....
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Recent progress in fragment-based drug discovery facilitated by NMR spectroscopy
May 2022
Considerable developments have been observed in fragment-based lead/drug discovery (FBLD/FBDD) recently, with four drugs approved and many others under investigation. Nuclear magnetic resonance (NMR)...
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Amide proton transfer imaging of Alzheimer's disease and Parkinson's disease
February 2023
Amide proton transfer (APT) magnetic resonance imaging (MRI) is an important molecular imaging technique at the protein level in tissue. Neurodegenerative diseases have a high likelihood of causing...
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Structural analysis of silk using solid-state NMR
Available online 9 February 2024
Silkworms and spiders are capable of generating fibers that are both highly durable and elastic in a short span of time, using a silk solution stored within their bodies at room temperature and normal...
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Specific protein-urea interactions
August 2022
The mechanism of urea's action in protein denaturation remains largely unknown. To provide an experimental basis for molecular dynamics (MD) simulations on urea-protein interactions, we investigated...
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Qualitative analysis of aromatic compounds via 1D TOCSY techniques
February 2024
The aromatic compounds, including o-xylene, m-xylene, p-xylene, and ethylbenzene, primarily originate from the catalytic reforming of crude oil, and have a wide variety of applications. However, because...
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Multinuclear MR and MRI study of lithium-ion cells using a variable field magnet and a fixed frequency RF probe
February 2024
An exploratory multinuclear magnetic resonance (MR) and magnetic resonance imaging (MRI) study was performed on lithium-ion battery cells with 7Li, 19F, and 1H measurements. A variable field superconducting...
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Non-invasive assessment for intratumoural distribution of interstitial fluid flow
November 2023
Interstitial fluid plays a vital role in drug delivery and tumour treatment. However, few non-invasive measurement methods are available for measuring low-velocity biological fluid flow. Therefore,...
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Prospects of borehole NMR instruments and applications
November 2022
Borehole nuclear magnetic resonance (NMR) is a powerful technology to characterize the petrophysical properties of underground reservoirs in the petroleum industry. The rising complexity of oil and...
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Recent advances on surface metal hydrides studied by solid-state nuclear magnetic resonance spectroscopy
February 2023
Metal hydrides (M–H) on solid surfaces, i.e., surface M–H, are ubiquitous but critical species in heterogeneous catalysis, and their intermediate roles have been proposed in numerous reactions such...
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