Incorporating omics-based tools into endophytic fungal research
2024
Fungal endophytes are valuable sources of bioactive compounds with diverse applications. The exploration of these compounds not only contributes to our understanding of ecological interactions but also...
Share article
Organ-on-chip technology: Opportunities and challenges
2024
Organ-on-chip (OOC) technology is an innovative approach that reproduces human organ structures and functions on microfluidic platforms, offering detailed insights into intricate physiological processes....
Share article
Identifying Chlorella vulgaris and Chlorella sorokiniana as sustainable organisms to bioconvert glucosamine into valuable biomass
2024
Chitin is a major component of various wastes such as crustacean shells, filamentous fungi, and insects. Recently, food-safe biological and chemical processes converting chitin to glucosamine have been...
Share article
Engineered microbial consortia for next-generation feedstocks
2024
Addressing urgent environmental challenges, this commentary emphasizes the need for green, bio-based solutions in chemical production from renewable feedstocks. It highlights advanced metabolic engineering...
Share article
Antibiotic susceptibility and virulence factors of bacterial species among cancer patients
2024
Antibiotic resistance is one of the most significant challenges of the 20-s century, and the misuse of antibiotics is a driver of antimicrobial resistance. This study aimed to assess the prevalence...
Share article
A comprehensive study on anaerobic digestion of organic solid waste: A review on configurations, operating parameters, techno-economic analysis and current trends
2024
The excessive discharge and accumulation of solid organic waste into the environment is of severe concern across the globe. Thus, an efficient waste management system is important to mitigate health...
Share article
Understanding virus retention mechanisms on protein a chromatography based on using different wash buffers – Evaluating the possibility for a generic wash buffer toolbox to improve virus clearance capacity
2024
During manufacturing of mammalian-cell derived monoclonal antibodies (mAbs) virus clearance capacity of the downstream process has to be demonstrated. The protein A chromatography step typically achieves...
Share article
CRISPR/Cas9 improves targeted knock-in efficiency in Aspergillusoryzae
2024
Aspergillus oryzae is an important fungus in food and industrial enzyme production. In A. oryzae, targeted knock-in transformation is primarily limited to homologous recombination (HR)-based systems,...
Share article
Harnessing gut cells for functional insulin production: Strategies and challenges
2023
Reprogrammed glucose-responsive, insulin + cells (“β-like”) exhibit the potential to bypass the hurdles of exogenous insulin delivery in treating diabetes mellitus. Current cell-based therapies-transcription...
Share article
SynBio Africa's story from the grassroots, the present, and the future
2023
SynBio Africa is a forum for researchers, students, citizen scientists, policymakers and the public to convene and develop successful pathways for the propagation of synthetic biology technologies,...
Share article
Over-expression of α-bisabolene by metabolic engineering of Yarrowia lipolytica employing a golden gate DNA assembly toolbox
2023
Yarrowia lipolytica is a modern workhorse for biotechnology that is amenable to genetic manipulations and can produce high levels of various enzymes. The present study was designed to engineer Y. lipolytica...
Share article
Potential application of menadione for antimicrobial coating of surgical sutures
2023
Staphylococcal-associated surgical site infections (SSI) are common nosocomial infections in healthcare facilities worldwide. The use of antiseptic-coated sutures has been recommended to minimise the...
Share article
Synthetic microbes and biocatalyst designs in Thailand
2023
Furthering the development of the field of synthetic biology in Thailand is included in the Thai government's Bio-Circular-Green (BCG) economic policy. The BCG model has increased collaborations between...
Share article
Synthetic biology in Indonesia: Potential and projection in a country with mega biodiversity
2023
Synthetic biology has gained many interest around the globe in the last two decades, not only due to its rapid development but also the potential to provide addressable solutions using standardized...
Share article
Characterization and bioactive component analysis of filamentous bacterium XJ-16
2023
Actinomycetes, which can produce a variety of bioactive compounds in the metabolic process, is one of the important sources of novel drugs, enzymes, anti-tumor drugs and enzyme inhibitors. It has been...
Share article
Circular mRNA: A novel therapeutic agent
2023
Circular mRNA (circmRNA) is a covalent closed loop formed by reverse splicing of the 3′ end to the 5′ end of mRNA. Compared to traditional linear mRNAs, circmRNAs can mediate efficient, stable, and...
Share article
Decoding dye degradation: Microbial remediation of textile industry effluents
2023
The extensive use of chemical dyes, primarily Azo and anthraquinone dyes, in textiles has resulted in their alarming release into the environment by textile industries. The introduction of heavy metals...
Share article
A facile microfluidic chip design for DNA detection using dengue serotypes as a proof-of-concept case study
2023
Dengue fever is caused by any of the four serotypes of dengue viruses, DENV-1, DENV-2, DENV-3 and DENV-4 spread by mosquito bites and is important to distinguish between them due to lack of cross-protective...
Share article
Rational engineering approaches for establishing insect olfaction reporters in yeast
2023
Insect olfaction directly impacts insect behavior and thus is an important consideration in the development of smart farming tools and in integrated pest management strategies. Insect olfactory receptors...
Share article
Suitability evaluation of toehold switch and EXPAR for cell-free MicroRNA biosensor development
2023
The development of a robust and cost-effective sensing platform for microRNA (miRNA) is of paramount importance in detecting and monitoring various diseases. Current miRNA detection methods are marred...
Share article
Share article
Metabolic engineering of Escherichia coli to utilize methanol as a co-substrate for the production of (R)-1,3-butanediol
2023
Due to its abundance, cost-effectiveness, and high reducibility, methanol has gained considerable attention in the biomanufacturing industry as a nonfood feedstock for the production of value-added...
Share article
2023 The 1st National Competition of “Bloomag Cup” in CO2 capture, conversion, and utilization
2023
The inaugural National Competition for Carbon Dioxide Capture, Conversion and Utilization Innovation (“Bloomag Cup”) was successfully held on July 30, 2023 in Beijing. This competition was initiated...
Share article
The electrical transport and antibacterial properties of Fe doped MgO nanoparticles synthesized by a soft chemical technique
2023
Fe doped MgO nanoparticles were synthesized using a straightforward soft chemical method. We conducted a comprehensive examination of the electrical properties of Fe-doped MgO nanoparticles with a crystalline...
Share article
Bio-conversion of organic wastes towards polyhydroxyalkanoates
2023
The bio-manufacturing of products with substantial commercial value, particularly polyhydroxyalkanoates (PHA), using cost-effective carbon sources through microorganisms, has garnered heightened attention...
Share article