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Guide for Authors

INTRODUCTION

Editorial Process

All manuscripts received are duly acknowledged. Upon submission, the Editorial Office will check the manuscript's conformity to technical quality and author guidelines, typically within one week. Manuscripts with insufficient conformity are returned to authors for revision. Manuscripts with insufficient originality, serious scientific or experimental flaws, or lack of interest to the readership of Frontiers in Laboratory Medicine will be rejected by the Editor-in-chief and /or Deputy Editor-in-Chief without further peer review. Manuscripts deemed suitable for publication are sent to the Executive Associate Editors. The Executive Associate Editors will make initial assessment and will serve as the managing editor, who in turn will appoint 2-3 editorial board members and /or external referees to complete peer reviews within 4 weeks. Based on the recommendations and comments made by peer reviewers, the Executive Associate Editor will make a formal recommendation to the Editor-in-Chief and /or Deputy Editor-in-Chief who will make the final decision within 1 week, in consultation with other editorial board members, if deemed necessary. The comments and recommendations (acceptance/rejection/minor revision/major revision in manuscript ) received from reviewers are conveyed to the corresponding author. If necessary, the author is required to provide a point by point response to reviewers' comments and submit a revised manuscript. This process will be repeated till reviewers and editors are satisfied with the revised manuscript.

Manuscripts accepted for publication are copy edited for grammar, punctuation, print style, and format. Page proofs are sent to the corresponding author. The corresponding author is expected to return the corrected proofs within 48 hours. The whole process of submission of the manuscript, final decision, sending and rec, the journal publishes articles online as 'Ahead of Print' immediately upon acceptance.

During submission, the contributor is requested to provide names of at least three qualified reviewers who have had experience in the subject of the submitted manuscript. The reviewers should not be affiliated with the same institutes as the contributor/s. However, the selection of these reviewers is at the sole discretion of the editor.

Contact Details for Submission

Paper should be submitted using the Frontiers in Laboratory Medicine online submission system, (preparing ). For questions on the submission and reviewing process, please contact the Editorial Office at: frontlabmed@yahoo.com; frontlabmed@tmmu.edu.cn; telephone +86-023-68754429; 18512371269.

Types of article

Contributions falling into the following categories will be considered for publication: full length research article, review article, technical note, short communication, correspondence, short communication, commentary, book review, and case report.
Please ensure that you select the appropriate article type from the list of options when making your submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.

BEFORE YOU BEGIN

Submission declaration and verification

Submission of an article implies that the work described has not been published previously (except in the form of an abstract or as part of a published lecture or academic thesis or as an electronic preprint, see Multiple, redundant or concurrent publication' section of our ethics policy for more information), that it is not under consideration for publication elsewhere, that its publication is approved by all authors and tacitly or explicitly by the responsible authorities where the work was carried out, and that, if accepted, it will not be published elsewhere in the same form, in English or in any other language, including electronically without the written consent of the copyright-holder. To verify originality, your article may be checked by the originality detection service CrossCheck.

External Reviewers

Please submit the names, institutional affiliations. and e-mail addresses of at least 3 potential external reviewers as well as a brief description of their expertise relevant to your manuscript. Suggested reviewers should be individuals qualified to evaluate the work you have submitted. The reviewers suggested may not be current, recent or extensive collaborators of yours, and must not be involved in the preparation of the manuscript. Reviewers must not be members of the same institution as the authors. Editorial Board members of Frontiers in Laboratory Medicine should not be named as suggested reviewers.
Please note that the editor retains the sole right to decide whether or not the suggested reviewers are used. Failure to provide appropriate reviewer suggestions may result in your manuscript being returned to you without being reviewed. Authors may request exclusion of certain reviewers if Competing interests are anticipated. However, no more than 3 such names should be given. Entire groups or institutions cannot be specified for exclusion.

Ethical Approval

For manuscripts reporting studies involving human subjects, Statements identifying the committee approving the studies and confirming that informed consent was obtained from all subjects must appear in the Experimental Procedures section. All experiments on live vertebrates or higher invertebrates must be performed in accordance with relevant institutional and national guidelines and regulations. In the manuscript, a statement identifying the committee approving the experiments and confirming that all experiments conform to the relevant regulatory standards must be included in the Experimental Procedures section. The editors reserve the right to seek comments from reviewers or additional information from authors on any cases in which concerns arise. For more information on ethics in publishing and ethical guidelines for journal publication see https://www.elsevier.com/publishingethics and https://www.elsevier.com/journal-authors/ethics.

Report of Clinical Trials

All randomized controlled trials submitted for publication should include a complete Consolidated Standards of Reporting Trials (CONSORT) flow chart (available at http://www.consort.statement.org). This Journal has adopted the proposal from the International Committee of Medical Journal Editors (ICMJE) that requires, as a condition of consideration for publication of clinical trials, registration in a public trials registry. Purely observational studies (those in which the assignment of the medical intervention is not at the discretion of the investigator) do not require registration. Further information can be found at http://www.icmje.org.

Identification of Patients in Descriptions, Photographs and Pedigrees

A signed statement of informed consent to publish (in print and online) patient descriptions, photographs and pedigrees should be obtained from all subjects (parents or legal guardians for minors) who can be identified (including by the subjects themselves) in such written descriptions, photographs or pedigrees. Such persons should be shown the manuscript before its submission. Omitting data or making data less specific to de-identify patients is acceptable, but altering or falsifying any such data is not acceptable.

Submit your article

Please submit your article via https://www.evise.com/profile/api/navigate/FLM.

Supporting Documents

The following documents must be included (refer also to the Check List that follows this guide for author):

  • Conflict of Interest Statement. You may use the form that follows this guide for authors.
  • Copyright Transfer Agreement. You may use the form that follows this guide for authors.
  • Authorship Statement. You may use the form that follows this guide for authors. All the authors' signatures must be included.
  • External Reviewer Suggestions. You may use the form that follows this guide for authors. AND, where applicable
  • Ethics Statement. Articles covering human or animal experiments must be accompanied by a letter of approval from the relevant review committee or authorities.
  • Consolidated Standards of Reporting Trials (CONSORT) flow chart for randomized controlled trials submitted for publication.
  • Articles where human subjects can be identified in descriptions, photographs or pedigrees must be accompanied by a signed statement of informed consent to publish (in print and online)the descriptions, photographs and pedigrees from each subject who can be identified.
  • Where material has been reproduced from other copyrighted sources, the letter(s) of permission from the copyright holder(s) to use the copyrighted sources must be supplied.

Additional Information

Tables and figures may be presented with captions within the main body of the manuscript; if so, figures should additionally be uploaded as high resolution files.

Ethics in publishing

For information on Ethics in publishing and Ethical guidelines for journal publication see https://www.elsevier.com/publishingethics and https://www.elsevier.com/journal-authors/ethics.

Conflict of interest

All authors are requested to disclose any actual or potential conflict of interest including any financial, personal or other relationships with other people or organizations within three years of beginning the submitted work that could inappropriately influence, or be perceived to influence, their work. See also https://www.elsevier.com/conflictsofinterest. Further information and an example of a Conflict of Interest form can be found at: http://service.elsevier.com/app/answers/detail/a_id/286/supporthub/publishing.

Use of inclusive language

Inclusive language acknowledges diversity, conveys respect to all people, is sensitive to differences, and promotes equal opportunities. Articles should make no assumptions about the beliefs or commitments of any reader, should contain nothing which might imply that one individual is superior to another on the grounds of race, sex, culture or any other characteristic, and should use inclusive language throughout. Authors should ensure that writing is free from bias, for instance by using 'he or she', 'his/her' instead of 'he' or 'his', and by making use of job titles that are free of stereotyping (e.g. 'chairperson' instead of 'chairman' and 'flight attendant' instead of 'stewardess').

Changes to authorship

Authors are expected to consider carefully the list and order of authors before submitting their manuscript and provide the definitive list of authors at the time of the original submission. Any addition, deletion or rearrangement of author names in the authorship list should be made only before the manuscript has been accepted and only if approved by the journal Editor. To request such a change, the Editor must receive the following from the corresponding author: (a) the reason for the change in author list and (b) written confirmation (e-mail, letter) from all authors that they agree with the addition, removal or rearrangement. In the case of addition or removal of authors, this includes confirmation from the author being added or removed.

Only in exceptional circumstances will the Editor consider the addition, deletion or rearrangement of authors after the manuscript has been accepted. While the Editor considers the request, publication of the manuscript will be suspended. If the manuscript has already been published in an online issue, any requests approved by the Editor will result in a corrigendum.

Copyright

Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement' (for more information on this and copyright, see https://www.elsevier.com/copyright). An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.

Author rights
As an author you (or your employer or institution) have certain rights to reuse your work. For more information on author rights please see https://www.elsevier.com/copyright.

Open access

Every peer-reviewed research article appearing in this journal will be published open access. This means that the article is universally and freely accessible via the internet in perpetuity, in an easily readable format immediately after publication. The author does not have any publication charges for open access. South West Hospital and Laboratorial Medicine Committee of the Chinese Research Hospital Association will pay to make the article open access.
A CC user license manages the reuse of the article (see https://www.elsevier.com/openaccesslicenses).
All articles will be published under the following license:

Creative Commons Attribution-NonCommercial-NoDerivs (CC BY-NC-ND)
For non-commercial purposes, lets others distribute and copy the article, and to include in a collective work (such as an anthology), as long as they credit the author(s) and provided they do not alter or modify the article.

Elsevier Publishing Campus
The Elsevier Publishing Campus (www.publishingcampus.com) is an online platform offering free lectures, interactive training and professional advice to support you in publishing your research. The College of Skills training offers modules on how to prepare, write and structure your article and explains how editors will look at your paper when it is submitted for publication. Use these resources, and more, to ensure that your submission will be the best that you can make it.

Language and language services

Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientific English may wish to use the English Language Editing service available from Elsevier's WebShop (http://webshop.elsevier.com/languageediting/) or visit our customer support site (http://support.elsevier.com) for more information.

Submission

Our online submission system guides you stepwise through the process of entering your article details and uploading your files. The system converts your article files to a single PDF file used in the peer-review process. Editable files (e.g., Word, LaTeX) are required to typeset your article for final publication. All correspondence, including notification of the Editor's decision and requests for revision, is sent by e-mail.

PREPARATION

Cover Letter

Submissions should be accompanied by a one-page cover letter from the corresponding author including full postal address, telephone number and e-mail address. This letter should contain a brief explanation of the conceptual advance provided by the findings and the significance of the findings to a broad readership.
The cover letter should state clearly that:

  • the reported work, in whole or in part, has not been under consideration for publication by any other primary scientific journals;
  • all authors have read and concurred with the content of the manuscript.

Full Length Article

These may be randomized trials, intervention studies. studies of screening and diagnostic tests, laboratory and animal studies, cohort studies, cost-effectiveness analyses, case-control studies, and surveys with high response rates. which represent new and significant contributions to the field. Section headings should be: Abstract, Introduction, Material and Methods, Results, Discussion, Acknowledgments and Appendix (if applicable), and References. The Introduction should provide a brief background to the subject of the paper, explain the importance of the study, and state a precise study question or purpose. The Material and Methods section should describe the study design and methods (including the study setting and dates, patients/ participants with inclusion and exclusion criteria, or data sources and how these were selected for the study, patient samples or animal specimens used, explain the laboratory methods followed ), and state the statistical procedures employed in the research. The Results section should comprise the study results presented in a logical sequence, supplemented by tables and/or figures. Take care that the text does not repeat data that are presented in tables and/ or figures but only emphasize and summarize the essential features of any interventions, the main outcome measures, and the main results. The Discussion section should be used to emphasize the new and important aspects of the study, placing the results in context with published literature, the implications of the findings, and the conclusions that follow from the study results. Typical length: no more than 6000 words, 40-80 references.

Review Article

Review Article in Frontiers in Laboratory Medicine are solicited and commissioned by the Editor. In Chief and subject to peer review. The reviews provide an insightful overview of the recent advances in a particular field or area in experimental and translational medical research interesting to the specialist readership. Authors wishing to submit an unsolicited Review are encouraged to contact the editorial office prior to submission. Review articles are limited to 6,000 words, not counting an abstract of 200 words or fewer, as well as the figure legends and the references. It may not exceed a total of 4 tables/figures.

Short Communication

Short manuscripts documenting high impact experimental results will be considered for publication as this category. Short manuscripts submitted for consideration are subject to the same rigorous peer review as for Original Articles. Short Communication may not exceed 2,000 words of text not counting the abstract, figure legends, and references; abstracts must not exceed 150 words and should be presented as a single paragraph with no subheadings. Only 4 figures/tables and 30 references may be included. The format of a Short Communication follows that of a Full Length Article. but the Results and Discussion are included in a single section.

Correspondence

Should a reader have constructive comments or criticisms relevant to a paper published in Frontiers in Laboratory Medicine,. it may be accepted for publication in the form of correspondence after a fast-track editorial review. The Correspondence may not exceed a word limit of 1000, with no more than 10 references. The Correspondence may be published together with the response from the authors of the original paper(s) under discussion. The items of correspondence may be edited by the editor prior to the publication.

Perspectives
Perspectives are short, commissioned scholarly reviews and discussions of the primary research article(s) that are too technical for a Commentary but do not meet the criteria for a Review because of the narrow scope. The highlighted research article(s) may appear in the same or recent issue of Frontiers in Laboratory Medicine, or in other major 10urnals. Perspectives offer a point of view on a topic of current interest. They can be speculative and creative, and are meant to stimulate thought on a topic of interest to our readership. They are short, thoughtful, and to the point. They are not intended as comprehensive reviews of the literature. The text should not exceed 1,500 words, including up to two figures/tables. References are limited to 20. Perspectives authors must provide a competing financial interests statement before publication. Perspectives are usually peer reviewed.

Commentary
As a flexible format, Commentaries are short, opinion articles commissioned by the Editors. The main criteria are that they should be of immediate interest to a broad readership and should be written in an accessible, non. technical style. In some cases. Commentaries accompany a primary research article in Frontiers in Laboratory Medicine to highlight an exceptional advance or to discuss a controversy in the field. They may also focus on article(s) of exceptional significance that are published elsewhere. Commentaries do not normally contain primary research data. Their length is usually limited to 1,000 words and may include one figure or table. References are limited to 10. Commentary authors must provide a competing financial interests statement before publication. Commentaries may be peer reviewed at the editor's discretion.

Views on News

Views on News are commissioned by the Editors only. They may be linked to articles in Frontiers in Laboratory Medicine. or they may focus on article(s) of exceptional significance that are published elsewhere. Their Length is usually limited to 800 words. References are limited to 10. Views on News are not peer reviewed. Authors must provide a competing financial interests statement before publication.

Research Watch Research Watch is a format for short commissioned summaries of recent publications of exceptional and broad significance in major life science and biomedical journals. The text should not exceed 500 words with no more than 5 references. Research Watch summaries are not peer reviewed.

Statistical Requirements

Statistical analysis is essential for all research papers except case reports. Use correct nomenclature of statistical methods (e.g., two sample t test, not unpaired t test). Descriptive statistics should follow the scabs used in data description. Inferential statistics are important for interpreting results and should be described in detail. All P values should be expressed to 2 digits to the right of the decimal point, unless P< 0.01. in which case the P value should be expressed to 3 digits to the right of the decimal point. The smallest P value that should be expressed is P< 0.001. since additional zeros do not convey useful information: the largest P value that should be expressed is P> 0.99.

Abbreviations
Define abbreviations that are not standard in this field in a footnote to be placed on the first page of the article. Consult Frontiers in Laboratory Medicine' List of Abbreviations and the pertinent literature for accepted abbreviations, especially for genes and proteins;list all those used, even if already in Frontiers in Laboratory Medicine' list (create new abbreviations if necessary). Be meticulous with symbols. For proteins, use Roman letters with at least the first letter capitalized (e.g., Hprt, HPRT or ?Gal ) for genes (or DNA) use italicized letters (e.g., lacZ, hprt, HPRT or cat gene, not HPRT or CAT gene). Consult the nomenclature (or usage) for the particular organism concerned to use (or create) proper gene/ protein abbreviations. Ensure consistency of abbreviations throughout the article.

Further considerations

  • Manuscript has been "spell-checked" and "grammar-checked"
  • Color figures are clearly marked as being intended for color reproduction on the Web (free of charge) and in print or to be reproduced in color on the Web (free of charge) and in black-and white in print
  • If only color on the Web is required, black and white versions of the figures are also supplied for printing purposes
For any further information please visit our customer support site at http://support.elsevier.com.

Peer Review

This journal operates a single blind review process. All contributions are sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is final. More information on types of peer review.

Use of Word Processing Software

It is important that the file be saved in the native format of the word-processor used. The text should be in single-column format. Keep the layout of the text as simple as possible. Most formatting codes wilt be removed and replaced on processing the article. In particular, do not use the word-processor's options to justify text or to hyphenate words. However do use bold face, italics, subscripts, superscripts, etc. When preparing tables, if you are using a table grid, use only one grid for each individual table and not a grid for each row, If no grid is used, use tabs, not spaces, to align columns. The electronic text should be prepared in a way very similar to that of conventional manuscripts (see also the Guide to Publishing with Elsevier: https://www.elsevier.com/guidepublication). Note that individual source riles of figures, tables and text graphics will be required whether or not you embed your figures in the text. See also the section on electronic illustrations. To avoid unnecessary errors you are strongly advised to use the spell-check and "grammar-check" functions of your word processor.

LaTex

You are recommended to use the Elsevier article class elsarticle.cls (http://www.ctan.org/ tex-archive/macros/latex/contrib/elsarticle) to prepare your manuscript and BibTex (http://www.Bibtex.org) to generate your bibliography.

For detailed submission instructions, templates and other information on LaTex, see https://www.elsevier.com/latex.

Article structure

Article Structure

Subdivision - numbered sections
Divide your article into clearly defined and numbered sections. Subsections should be numbered 1.1 (then 1.1.1, 1.1.2, ...), 1.2, etc. (the abstract is not included in section numbering). Use this numbering also for internal cross-referencing: do not just refer to "the text". Any subsection may be given a brief heading. Each heading should appear on its own separate line.

Introduction
State the objectives of the work and provide an adequate background, avoiding a detailed Literature survey or a summary of the results.

Material and Methods
Provide sufficient detail to allow the work to be reproduced. Methods already published should be indicated by a reference: only relevant modifications should be described.

Results
Results should be clear and concise.

Discussion
This should explore the significance of the results of the work, not repeat them. A combined Results and Discussion section is often appropriate. Avoid extensive citations and discussion of published literature.

Conclusion
The main conclusions of the study may be presented in a short Conclusions section, which may stand alone or form a subsection of a Discussion or Results and Discussion section.

Appendices

If there is more than one appendix, they should be identified as A, B, etc. Formulas and equations in appendices should be given separate numbering: Eq. (A.l), Eq. (A.2), etc.; in a subsequent appendix, Eq. (B.1) and so on. Similarly for tables and figures: Table A.1; Fig.A.1, etc.

Essential Title Page Information

  • Title. Concise and informative. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible.
  • Author names and affiliations. Where the family name may be ambiguous (e.g., a double name), please indicate this clearly. Present the authors' affiliation addresses (where the actual work was done) below the names. Indicate all affiliations with a lower-case superscript letter immediately after the author's name and in front of the appropriate address. Provide the full postal address of each affiliation, including the country name, and, if available, the e-mail address of each author.
  • Corresponding author. Clearly indicate who will handle correspondence at all stages of refereeing and publication, also post-publication. Ensure that telephone and fax numbers (with country and area code) are provided in addition to the e-mail address and the complete postal address. Contact details must be kept up to date by the corresponding author.
  • Present/permanent address. If an author has moved since the work described in the article was done, or was visiting at the time, a "Present address" (or "Permanent address") may be indicated as a footnote to that author's name. The address at which the author actually did the work must be retained as the main, affiliation address. Superscript Arabic numerals are used for such footnotes.

Abstract and Keywords
Abstracts should be no more than 250 words in length. Abstracts for Full Length Articles should be unstructured with a concise description of relevant background, appropriate materials and methods used to obtain the results, and major findings and conclusions. Abstracts for Review Articles and Short Communication should be unstructured. Abbreviations and reference citations should be avoided. Below an abstract, at least 5 relevant keywords should also be provided in alphabetical order.

Submission checklist

Only complete manuscript submissions will be considered for publication.
Complete submission must include:

  • Cover Letter for manuscript submission
  • Authorship Statement signed by all authors
  • Signed Conflict of Interest disclosure statement
  • Signed Copyright Transfer Agreement
  • External Reviewer Suggestions.

AND, where applicable
  • Letter of approval from review committee for use of human samples in research and human experiments
  • Letter of approval from relevant authority for use of animals in experiments
  • CONSORT flow chart for randomized controlled trial
  • Signed consent to publish(online)from human subjects who can be identified in your manuscript
  • Letter(s)of permission from copyright holder(s) to use copyrighted sources in your Manuscript

In the actual article ensure that the following information is provided:
  • Title page
Article title
Name(s) and affiliation(s) of author(s)
Corresponding author details (name, e-mail address, full postal address, telephone and fax numbers)
  • Abstract: unstructured for Full Length Article; unstructured for Review Article and Short Communication within 300 words
  • At Least 5 relevant keywords in alphabetical order
  • Main text
  • References in the correct format. cited in numerical order, and all references in the List are cited in the Text/Tables/Figures, and vice versa

  • AND, where applicable
  • Acknowledgments
  • All tables (including title, description, footnotes).
  • All figure captions
  • Electronic picture riles of all figures; resolution of 300 dpi for halftone images, 500 dpi for combination art (halftone +line art), and 1000 dpi for line art.

Acknowledgements

Collate acknowledgments in a separate section at the end of the article before the references and do not, therefore, include them on the title page, as a footnote to the title or otherwise. List here those individuals who provided help during the research (e.g. , providing language help, writing assistance or proof reading the article, etc.).

Nomenclature and Units
Follow internationally accepted rules and conventions: use the international system of units (SI). If other quantities are mentioned, give their equivalent in SI. Authors wishing to present a table of nomenclature should do so on the second page of their manuscript.

Math Formula
Present simple formula in the line of normal text where possible and use the solidus (/) instead of a horizontal line for small fractional terms, e.g. , X/Y. In principle, variables are to be presented in italics. Powers of e are often more conveniently denoted by exp. Number consecutively any equations that have to be displayed separately from the text (if referred to explicitly in the text).

Footnotes
Footnotes should be used sparingly. Number them consecutively throughout the article, using superscript Arabic numbers. Many word-processors build footnotes into the text, and this feature may be used. Should this not be the case, indicate the position of footnotes in the text and present the footnotes themselves separately at the end of the article. Do not include footnotes in the Reference list. Table footnotes indicate each footnote in a table with a superscript lowercase letter.

Tables
Tables should supplement, not duplicate, the text. They should have a concise table heading, be self-explanatory, and numbered consecutively in the order of their citation in the text. Information requiring explanatory footnotes should be denoted using superscripted lowercase letters in alphabetical order (a, b, c, etc.). Asterisks (*,**) are used only to indicate the probability level of tests of significance. Abbreviations used in the table must be defined and placed after the footnotes. If you include a block of data or table from another source, whether published or unpublished, you must acknowledge the original source.

Artwork

Artwork & Media instructions

Submitting your illustrations, figures and other artwork (such as multimedia and supplementary files)in an electronic format helps us produce your work to the best possible standards. ensuring accuracy clarity and a high level of detail.
A detailed guide on electronic artwork is available on our website:
https://www.elsevier.com/author-schemas/artwork-and-media-instructions. You are urged to visit this site; some excerpts from the detailed information are given here.

Electronic artwork
General points

  • Make sure you use uniform lettering and sizing of your original artwork.
  • Save text in illustrations as ""graphics"" or enclose the font.
  • Only use the following fonts in your illustrations: Arial, Courier, Times, Symbol.
  • Number the illustrations according to their sequence in the text.
  • Use a logical naming convention for your artwork files.
  • Provide captions to illustrations separately.
  • Produce images near to the desired size of the printed version.
  • Submit each figure as a separate rite.

Formats

Regardless of the application used, when your electronic artwork is finalized, please 'save as' or convert the images to one of the following formats (note the resolution requirements for line drawings, halftones, and line/halftone combinations given below):
EPS (or PDF): Vector drawings. Embed the font or save the text as 'graphics'.
TIFF(or JPG): Color or grayscale photographs (halftones):always use a minimum of 300 dpi.
TIFF(or JPG): Bitmapped line drawings:use a minimum of 1000 dpi.
TIFF(or JPG): Combinations bitmapped line/half-tone (color or grayscale): a minimum of 500 dpi is required. Please do not:
  • Supply files that are optimized for screen use (e.g. , Gif, BMP, PICT, WPG); the resolution is too low.
  • Supply files that are too low in resolution.
  • Submit graphics that are disproportionately large for the content.

Color Artwork

Color Artwork
Please make sure that artwork files are in an acceptable Format (TIFF, EPS or MS Office files) and with the correct resolution. If, together with your accepted article, you submit usable color figures then Elsevier will ensure, at no additional charge, that these figures will appear in color on the Web (e.g. , ScienceDirect and other sites) regardless of whether or not these illustrations are reproduced in color in the printed version.

Figure Captions
Ensure that each illustration has a caption. Supply captions separately, not attached to the figure. A caption should comprise a brief title(not on the figure itself)and a description of the illustration. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used.

References

References

Indicate references by (consecutive) superscript Arabic numerals in the order in which they appear in the text. The numerals are to be used outside periods and commas, inside colons and semicolons. Frontiers in Laboratory Medicine is currently using the Journal of American Medical Association (JAMA) reference style. For further detail and examples, please refer to the AMA Manual of Style, A Guide for Authors and Editors, Ninth Edinon, ISBN 0-683-40206-4, copies of which may be ordered from Lippincott Williams ?Wilkins (http://www.lww.com/index.html).

List: number the references in the list in the order in which they appear in the text.
Examples:

Reference to a journal publication:
1. Van der Geer J, Hanraads JAJ, Lupton RA. The art of writing a scientific article. J Sci Commun. 2000; 163:51-59.

Reference to a book:
2. Strunk W Jr, White EB. The Elements of Style. 3rd ed. New York, NY: Macmillan; 1979.

Reference to a chapter in an edited book:
3. Mettam GR, Adams LB. How to prepare an electronic version of your article. In: Jones BS, Smith RZ, eds. Introduction to the Electronic Age. New York, NY: E-Publishing Inc; 1999: 281-304.

AFTER ACCEPTANCE

Use of the Digital Object Identifier

The Digital Object Identifier (DOI) may be used to cite and link to electronic documents. The DOI consists of a unique alpha-numeric character string which is assigned to a document by the publisher upon the initial electronic publication. The assigned DOI never changes. Therefore, it is an ideal medium for citing a document, particularly 'Articles in press' because they have not yet received their full bibliographic information. The correct format for citing a DOI is shown as follows (example taken from a document in the journal Physics Letters B): dot:10.1016/j.physletb.2010.09.059. When you use the DOI to create URL hyperlinks to documents on the web, they are guaranteed never to change.

Proof

One set of page proofs (as PDF files) will be sent by e-mail to the corresponding author or, a link will be provided in the e-mail SO that authors can download the files themselves. Elsevier now provides authors with PDF proofs which can be annotated; for this you will need to download Adobe Reader version 7 (or higher) available free from http://get.Adobe.corn/reader. Instructions on how to annotate PDF files will accompany the proofs(also given on line). The exact system requirements are given at the Adobe site:http://www.adobe.com/products/reader/tech-specs.html. Please use this proof only for checking the typesetting, editing, completeness and correctness of the text, tables and figures. Significant changes to the article as accepted for publication will only be considered at this stage with permission from the Editor. We will do everything possible to get your article published quickly and accurately, please let us have all your corrections within 48 hours. It is important to ensure that all corrections are sent back to us in one communication. Please check carefully before replying, as inclusion of any subsequent corrections cannot be guaranteed. Proof-reading is solely your responsibility. Note that Elsevier may proceed with the publication of your article if no response is received.

Author Inquiries

For inquiries relating to the submission of articles (including electronic submission ) please visit the Frontiers in Laboratory Medicine homepage. For detailed instructions on the preparation of electronic artwork, please visit https://www.elsevier.com/artworkinstructions. Contact details for questions arising after acceptance of an article, especially those relating to proofs, writ be provided by the publisher. You can track accepted articles at https://www.elsevier.com/trackerticle.
You can also check our Author FAQs at https://www.elsevier.com/authorFAQ and/or contact Customer Support via http://support.elsevier.com.

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