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ISSN: 2590-2806

Urine proteome of COVID-19 patients

The atypical pneumonia (COVID-19) caused by SARS-CoV-2 is a serious threat to global public health. However, early detection and effective prediction of patients with mild to severe symptoms remain...

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The potential of spot and overnight urine in the evaluating of proteinuria and electrolyte

Urine testing has been a primary standard clinical method for assessing proteinuria and electrolyte intake. The traditional 24 ​h urine collection method, despite its high accuracy, has some limitations...

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Comparison laser anatomical endoscopic enucleation of the prostate (LAEEP) and transurethral resection of the prostate (TURP) in BPH treatment: A meta-analysis

Laser anatomical endoscopic enucleation of the prostate (LAEEP) is one of the alternative surgical procedures other than TURP for benign prostate hyperplasia (BPH). However, the consideration for clinical...

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Perspectives in urine AD7c-NTP: A biomarker for Alzheimer's disease

Biomarkers are important for early diagnosis of Alzheimer's disease (AD) in routine clinical practice and research. Alzheimer-associated neuronal thread protein (AD7c-NTP) is a member of the “neuronal...

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Urine concentration in elderly women and men

The degree of urine concentration, which is of relevance to healthcare, is higher in middle-aged males than in females, but whether this difference remains in elderly hospital patients is unknown. Urine...

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Urine metabolome reveals candidate biomarkers for divergent residual feed intake in beef cattle

We analyzed the amine/phenol-metabolome of urine samples to identify urinary metabolic biomarkers associated with residual feed intake in beef cattle. A group of 56 crossbred growing beef steers (average...

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NF-κB gene expression in peripheral blood and urine in early diagnosis of diabetic nephropathy – A liquid biopsy approach

Diabetic nephropathy (DN) is a pathological condition that affects diabetic patients around the world, and it is the main cause of chronic kidney diseases. It is known that the inflammatory pathway...

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Using one-to-many urine proteome comparisons to provide clues for fever of unknown origin

To provide diagnostic evidence and clues for patients with fever of unknown origin (FUO) through urine proteomics analysis....

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Comments on: Huang S. et al. “Biofluid Biomarkers of Alzheimer's disease: Progress, problems, and perspectives.” Neuroscience Bulletin (2022)

This paper by Huang S., et al. has retrospectively described the recent progress in biomarkers based on the A-T-N-X framework, A-T-N respectively represents Amyloid-Tau-Neurodegeneration, X represents...

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Urinary metabolomic and proteomic analyses in a mouse model of prostatic inflammation

Lower urinary tract symptoms (LUTS) are common among aging men. Since prostatic inflammation is one of its etiologies, it is plausible that urinary metabolite and protein biomarkers could be identified...

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Hematuria as a possible clinical presentation in monkeypox

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The devil is in the detail

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A matter of perspective—Cutting-edge technology-driven urine proteome in COVID-19

In a recent issue of Nature Communications, we highlighted in-depth urine proteomic research in which significant immunosuppression was revealed in early SARS-CoV-2- infected patients 1. The application...

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Identification of potential urinary exposure markers for the toxicant diisononyl phthalate in rubber worker urine specimens by high-resolution mass spectrometry-based metabolomics

Diisononyl phthalate (DiNP) is commonly used as a plasticizer in polyvinyl chloride (PVC) products. However, DiNP can interfere with the human endocrine system and is listed as a chemical with reproductive...

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Changes in the urine proteome in patients with advanced lung cancer after different drug treatments

Lung cancer is one of the most threatening diseases to human life and health because of its mortality. How to choose more efficient drugs and the appropriate timing of treatment for patients with advanced...

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Evaluation of the multicenter variations of urinary metabolomics

Multicenter experiments have frequently been performed in clinical biomarker studies. However, center effects should not be ignored. In this study, for the first time,we estimated the multicenter variations...

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Comments on: Saenger T. et al. “Urinary Biomarkers for Orange Juice Consumption.” Molecular Nutrition & Food Research (2021)

This paper by Saenger T., et al. has suggested the potential biomarkers for orange juice consumption and addressed an approach to distinguish between low, medium, and high orange juice consumption....

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Era of URINE

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The start of diabetes insipidus?

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Effect of vancomycin, teicoplanin, and linezolid on renal function of critically ill patients with sepsis

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