Hernia Mesh and Hernia Repair: A Review
2020
Hernia repair for primary and incisional hernia is the most commonly performed abdominal surgery done with extremely high costs. Treatment for hernia requires surgery to close the defect; however, there...
Orthopedic implants and devices for bone fractures and defects: Past, present and perspective
2020
Bone is a unique tissue that is capable of repairing itself after damage. However, there are certain instances of fractures and defects that require clinical intervention for proper alignment and healing....
Applications of PLA in modern medicine
2020
Polylactic acid (PLA) is a versatile biopolymer. PLA is synthesized with ease from abundant renewable resources and is biodegradable. PLA has shown promise as a biomaterial in a plethora of healthcare...
PETG: Applications in Modern Medicine
March 2024
•PETG is a miscible, transparent thermoplastic with strong tensile properties, high ductility, and favorable resistance to heat and chemical insults.•PETG is an inexpensive and versatile biomaterial.•3D...
Wound dressing products: A translational investigation from the bench to the market
June 2022
•Designing advanced cost-effective wound dressings is an urgent need worldwide.•Promising in vitro and in vivo results are not often confirmed by Clinical Trials.•The use of personalized treatments...
Engineered artificial skins: Current construction strategies and applications
December 2023
•Give a detailed introduction of the cellular components, scaffold materials and bio-fabrication techniques involved in the construction of artificial skin.•Highlight the application for chronic wound...
Hyaluronic acid and its biomedical applications: A review
2020
Hyaluronic acid is a naturally occurring biopolymer possessing numerous functions within the body including wound repair, cell migration, and cell signaling. Due to its versatility, hyaluronic acid...
An Overview on Materials and Techniques in 3D Bioprinting Toward Biomedical Application
2021
•Synthetic polymers and bioinks are introduced with the application of 3D bioprinting in medical.•Common applicable biomaterials and 3D bioprinting techniques are classified.•Strengths and limitations...
Biomedical applications of gelatin methacryloyl hydrogels
2021
•GelMA hydrogels are introduced with their excellent biocompatibility, biodegradability, and moldability.•The biomedical applications of GelMA in various fields are introduced and discussed.•A critical...
Emerging microfluidic technologies for sperm sorting
June 2023
•A broad range of researches about sperm sorting with microfluidics were reviewed, and were classified into three types according to the sorting principle.•The properties of sperm and female reproductive...
Development of fish collagen in tissue regeneration and drug delivery
September 2022
•Marine-based collagen as a resealable replacement for mammal-based collagen.•Potential advantages of MC thanks to its amenable chemical properties.•Methods for preparation of collagen from different...
The role of Piezo1 and Piezo2 proteins in tissue engineering: A Comprehensive review
June 2024
•Piezo1 and Piezo2 are the two novel mechanosensitive ion channels found in humans.•Piezo's are a sizeable trimeric protein with a three-bladed, propeller-like structure.•Two models- ‘Force from filament’...
Supplemental mineral ions for bone regeneration and osteoporosis treatment
June 2023
•Summary on all the potentially beneficial nutrition elements for bone regeneration.•Daily supplementation suggestions and dose guidance of these nutrition elements.•In vitro and in vivo models and...
Applications of silk-based biomaterials in biomedicine and biotechnology
March 2024
•Here, we reported the various unique properties of silk and commercially available silk-based biomaterials.•This review focused on highlighting various biomedical applications of silk-based biomaterials...
Electrospun chitosan nanofibers for wound healing application
2021
•The fabrication of electrospun chitosan nanofibers with random and aligned fibrous structure were introduced.•The as-crosslinked electrospun chitosan nanofibers possess enhanced wet stability, improved...
3D Bioprinting with Live Cells
September 2022
•3D bioprinting is a means of producing artificial organ replacements.•3D bioprinting is a power tool for precision medicine for customized need.•Summary of live-cell printing methodologies, applications,...
Advancing engineered approaches for sustainable wound regeneration and repair: Harnessing the potential of green synthesized silver nanoparticles
September 2024
•Green synthesized silver nanoparticles have shown promising results in wound healing, promoting faster healing and reducing infection risk.•These environmentally friendly nanoparticles offer a sustainable...
Decellularized extracellular matrix: A promising strategy for skin repair and regeneration
December 2023
•The commonly utilized decellularization methods and the evaluation methods for cellular residues and bioactive molecules of dECM were introduced.•dECM derived from different sources, including humans,...
Advances in smart hybrid scaffolds: A strategic approach for regenerative clinical applications
2025
•3D hybrid scaffolds improve biocompatibility and biomechanical properties.•Nano-topography enhances cellular interactions and scaffold performance.•4D printing enables dynamic, stimuli-responsive tissue...
The Artificial Disc Nucleus and Other Strategies for Replacement of the Nucleus Pulposus: Past, Present and Future Designs for an Emerging Surgical Solution
June 2024
•Nucleus pulposus replacement is a developing surgical methodology for the treatment of pathology related to degeneration of intervertebral discs (IVDs).•Review of pathologies treated with this technology,...
Improved skin regeneration with acellular fish skin grafts
2020
Fish skin graft, a novel skin substitute, has seen a widespread clinical application since the approval for wound coverage by the FDA. Due to its properties in promoting wound healing and its efficient...
Polylysine complexes and their biomedical applications
March 2023
•This review summarized the advanced development of the synthesis strategies of PLL•This review introduces the biomedical fields, where PLL are mainly utilized, such as cargo delivery, tissue adhesives,...
Development and challenges of cells- and materials-based tooth regeneration
June 2022
•The common dental diseases and their treatment methods are introduced.•Various cells and materials used to realize tooth regeneration are summarized.•The mechanisms of tooth regeneration were also...
Pulsed electromagnetic field stimulation enhances neurite outgrowth in neural cells and modulates inflammation in macrophages
March 2024
•We applied pulsed electromagnetic field (PEMF) stimulation on nerve cells.•We screened different parameters and found the optimal ones to improve neurite outgrowth.•The same parameters had anti-inflammatory...
Application of TPMS structure in bone regeneration
2021
•Methods and materials for manufacturing TPMS scaffolds are introduced.•Properties (such as pore structure, permeability, mechanical property, and curvature) that affect the overall structure and bone...