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Recent Engineered Regeneration Articles

Recently published articles from Engineered Regeneration.

In silico analysis of RNA and small RNA sequencing data from human BM-MSCs and differentiated osteocytes, chondrocytes and tenocytes

Srinivas V. Koduru | Irina A. Elcheva | Ashley N. Leberfinger | Dino J. Ravnic

•Identification of transcriptomic changes in human bone marrow stem cells and their differentiation lineages.•Young adult's stem cells are more active and rapidly differentiate to their lineages.•Very...

An Overview on Materials and Techniques in 3D Bioprinting Toward Biomedical Application

S. Vanaei | M.S. Parizi | S. Vanaei | F. Salemizadehparizi | H.R. Vanaei

•Synthetic polymers and bioinks are introduced with the application of 3D bioprinting in medical.•Common applicable biomaterials and 3D bioprinting techniques are classified.•Strengths and limitations...

Nanoparticles as delivery vehicles for antiviral therapeutic drugs

Alexander Maus | Lia Strait | Donghui Zhu

•Nearly any antiviral drug delivery system can be nanoscaled to the effect of improved properties.•Efficacy of drug delivery can be improved using nanoparticles as delivery vehicles.•Nanoparticulate...

Biomedical applications of gelatin methacryloyl hydrogels

Yun Piao | Hengze You | Tianpeng Xu | Ho-Pan Bei | Imanuel Zvi Piwko | Yu Yan Kwan | Xin Zhao

•GelMA hydrogels are introduced with their excellent biocompatibility, biodegradability, and moldability.•The biomedical applications of GelMA in various fields are introduced and discussed.•A critical...

Hydrogen generating patch improves skin cell viability, migration activity, and collagen expression

Marina Safonov | Jing You | Jihyung Lee | Vladimir L. Safonov | Diana Berman | Donghui Zhu

Molecular hydrogen recently attracted lots of attention in biomedical community because of its abilities to modulate signal transduction, protein phosphorylation, and gene expression that enable its...

Orthopedic implants and devices for bone fractures and defects: Past, present and perspective

Tiffany Kim | Carmine Wang See | Xiaochun Li | Donghui Zhu

Bone is a unique tissue that is capable of repairing itself after damage. However, there are certain instances of fractures and defects that require clinical intervention for proper alignment and healing....

Hernia Mesh and Hernia Repair: A Review

Carmine Wang See | Tiffany Kim | Donghui Zhu

Hernia repair for primary and incisional hernia is the most commonly performed abdominal surgery done with extremely high costs. Treatment for hernia requires surgery to close the defect; however, there...

Engineering nanoparticles to overcome immunological barriers for enhanced drug delivery

Thomas Malachowski | Austin Hassel

Nanotechnology has recently gained traction in the medical field as a method of targeted delivery and timed release of therapeutic drugs. As interest in this field grows, design considerations of the...

Biomaterials for Adhesion in Orthopedic Applications: A Review

Younis Zaokari | Alicia Persaud | Amr Ibrahim

Adhesive biomaterials, historically, have had a wide range of applications in all medical fields. With the extensive variety of biomaterials with adhesion properties, the field of orthopedics benefits...

Current developments in biofilm treatments: Wound and implant infections

Yosman Dhar | Yangha Han

Biofilm formation in wounds and implants can have numerous negative effects on a patient's health, including delayed healing and implant removal. Current treatments for biofilms do not completely eradicate...

Applications of PLA in modern medicine

Vincent DeStefano | Salaar Khan | Alonzo Tabada

Polylactic acid (PLA) is a versatile biopolymer. PLA is synthesized with ease from abundant renewable resources and is biodegradable. PLA has shown promise as a biomaterial in a plethora of healthcare...

Conductive nanomaterials for cardiac tissues engineering

Wei Liu | Luming Zhao | Changyong Wang | Jin Zhou

Myocardial infarction (MI) is a worldwide disease with high incidence and high fatality rate. In the past decade, a lot of research work based on the method of cardiac tissues engineering has received...

Improved skin regeneration with acellular fish skin grafts

Gabriella Fiakos | Zeming Kuang | Evan Lo

Fish skin graft, a novel skin substitute, has seen a widespread clinical application since the approval for wound coverage by the FDA. Due to its properties in promoting wound healing and its efficient...

Hyaluronic acid and its biomedical applications: A review

Matthew Dovedytis | Zhuo Jie Liu | Samuel Bartlett

Hyaluronic acid is a naturally occurring biopolymer possessing numerous functions within the body including wound repair, cell migration, and cell signaling. Due to its versatility, hyaluronic acid...

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