Gut dysbiosis-induced cerebral clock suppression mediates deltamethrin immunotoxicity via the brain-thyroid-immune Axis
2027
The paradigm for understanding how environmental pollutants affect aquatic organisms is shifting from direct tissue damage to remote regulation via complex inter-system communication. However, the exact...
The ecotoxicity of environmental 6PPD exposure to Onychostoma macrolepis: A correlative water–gut microbial framework
2027
The tire antioxidant 6PPD is increasingly detected in traffic-impacted aquatic environments, yet its potential effects on native freshwater fish and associated microbial communities in inland river...
Benzothiazoles and benzotriazoles in the dust and human urine samples from the e-waste recycling industry: occurrence, distribution, and occupational exposure assessment
2027
Benzothiazoles (BTHs) and benzotriazoles (BTRs) are high production volume chemicals widely incorporated into electronic products, yet their environmental occurrence and potential occupational exposure...
Insights into the immunotoxicity of typical PPD and PPDQ compounds through integrating network toxicology and experimental validation
2027
The rapid expansion of the automotive industry has led to increasing environmental release of N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPDQ). Notably, N-isopropyl-N′-phenyl-1,4-phenylenediamine...
Differential physiological and biochemical responses to herbicide stress: Why Trachemys scripta elegans outperforms native turtles?
2027
Herbicide pollution poses a growing threat to freshwater ecosystems, yet their sublethal effects on freshwater turtles remain largely understudied. Invasive turtle species are considered to be more...
Associations between environmental endocrine-disrupting chemicals exposure and cardiometabolic markers: integrated epidemiological and in silico analyses
2027
Environmental endocrine-disrupting chemicals (EDCs) are increasingly implicated in cardiometabolic disorders. Conventional studies have focused on specific types of pollutants or individual cardiometabolic...
Tire wear particles amplify the transmission risk of antibiotic resistance genes in a soil–plant system by reshaping microbial communities
2027
Tire wear particles (TWPs) can drive the proliferation and dissemination of antibiotic resistance genes (ARGs) in soil–vegetable ecosystems. Clarifying how TWPs indirectly drive the cross-habitat transmission...
Enhanced adsorption of pharmaceuticals using coffee ground biochars via KHCO3 and urea pre-treatment: Effects of π-π interactions and hydrogen bonding
2027
Herein, combined potassium bicarbonate (KHCO3) and urea pretreatment was applied to coffee ground biochar (BC) to enhance its adsorption performance toward acetaminophen (ACT) and carbamazepine (CBZ)....
Developmental hepatotoxicity of liquid crystal monomers in zebrafish: hepatic lipid accumulation and metabolic disruption
2027
Liquid crystal monomers (LCMs), extensively used in electronic display manufacturing, are increasingly detected in environmental and human matrices; however, their potential developmental hepatotoxicity...
Multimedia occurrence and mixture reproductive exposure risks of liquid crystal monomers: Campus versus residential indoor environments
2027
Liquid crystal monomers (LCMs) are emerging indoor contaminants of concern for their potential adverse reproductive health effects on humans. However, data on LCM occurrence and mixture reproductive...
A food-web-centered framework for interpreting PFAS trophic magnification in aquatic ecosystems
2027
Reported trophic magnification factors (TMFs) for per- and polyfluoroalkyl substances (PFAS) vary substantially among aquatic food webs, complicating comparisons across compounds and ecosystems. Interpreting...
Multiscale disruption of byssal homeostasis in Mytilus coruscus co-exposed to Irgarol 1051 and polystyrene microplastics
2027
Irgarol 1051 is widely used as an antifouling agent and is environmentally persistent, while microplastics can adsorb dissolved contaminants and alter their toxicity. The attachment performance of the...
Rainbow trout blood as a hazard monitoring platform for biodegradable microplastics
2027
The increasing environmental application of biodegradable plastics (BPs) necessitates a deeper understanding of their systemic biological hazards. Here, we established peripheral blood as a potential...
Circulating in the oyster immune system: multi-compartment modeling reveals dynamic intercellular trafficking of biodegradable nanoplastics
2027
Studies of the cellular fate of nanoplastics (NPs) in bivalves commonly overlook the dynamic trafficking of particles among immune cells. Here, we established a multi-compartment kinetic framework using...
Root lipid–associated uptake and species responses decouple accumulation and toxicity of liquid crystal monomers in leafy vegetables
2027
Liquid crystal monomers (LCMs), released from electronic products and e-waste, can enter agroecosystems and accumulate in edible crops, raising concerns about crop health and food safety. However, how...
Trifluoroacetic acid induces thyroid damage and metabolic disorders in tadpoles: the perspectives of microstructural, physiological, transcriptomics, and metabolomics
2027
Trifluoroacetic acid (TFA), a typical ultra-short-chain per- and polyfluoroalkyl substance (PFAS), is widely distributed in aquatic environments. However, studies on the toxic effects and mechanisms...
Poly(methyl methacrylate) micro- and nanoplastics induce early mitochondrial dysfunction and cellular perturbations in Drosophila melanogaster
2027
Heterogeneous micro- and nanoplastic (MNPLs) mixtures, which consist of particles of varying sizes, shapes, and physical and chemical properties, represent the dominant form of environmental plastic...
Microplastics and environment-weighted ecological risk: synergistic response of marine sedimentary microorganisms in the East China Sea
2027
Microplastics (MPs) have emerged as a critical environmental threat to the East China Sea. Nevertheless, existing studies highlight a notable data gap regarding the distribution patterns of MPs in marine...
Impacts of drilling on soil and groundwater heavy metal pollution: A comprehensive review
2026
This review focuses on the environmental consequences of drilling activities, specifically concerning soil and groundwater contamination, biodiversity loss, and air and water pollution. Drilling operations...
Chlorine release induced by contact electrification between polyvinyl chloride microplastics and moist air
2026
Polyvinyl chloride (PVC) microplastics (MPs) are prevalent in the atmosphere and, as they migrate, inevitably interact with flowing moist air. Despite this, our understanding of the surface chemistry...
Generation mechanisms, environmental behaviors, and treatment technologies of conventional and emerging contaminants in landfill leachate: A review
2026
Landfill leachate, derived from municipal solid waste landfills, is generated by external factors (e.g., rainfall erosion, solar radiation) and internal processes (e.g., physical sedimentation, chemical...
Time-dependent toxicity and key toxic components of five neonicotinoid mixtures under environmental concentrations in the Yangtze River Basin
2026
Neonicotinoids (NEOs), as widely used insecticides, have raised increasing concerns regarding their ecological impacts. Current knowledge on the mixture toxicity of NEOs, particularly under environmental...
First in situ application of a non-invasive sampling approach to assess pesticide effects on amphibian enzymatic activities
2026
Amphibians are particularly vulnerable to pesticide exposures, according to numerous laboratory and field studies. Enzymatic activities in biological tissues and body condition are usually proposed...
A semi-enclosed bay as a pharmaceutical hotspot and an open strait as a regional reservoir: Contrasting pharmaceuticals and antibiotic resistance
2026
Pharmaceuticals and antibiotic resistance genes (ARGs) are increasingly recognized as emerging pollutants in coastal ecosystems, yet their contrasting behaviors in open straits versus semi-enclosed...
The differential cardiotoxicity effects and molecular mechanisms induced by two emerging organophosphorus flame retardants (EHDPP and DPHP) with similar parent structures in zebrafish
2026
Herein, we systematically compared the cardiotoxicity effects of two structurally similar organophosphate flame retardants (OPFRs; EHDPP and its major metabolite DPHP) using zebrafishi as a model organism....
