Evaluating the Economic and Social Impact of Coal Mine Phaseout in China
Available online 11 September 2025
Systematic and widespread coal mine phaseouts are imperative to facilitating the transition from coal dependence in China. However, regional disparities in economic reliance on coal and environmental...
Continuous dynamic microforce reconstruction using electrical stimulation for remote pulse diagnosis
Available online 9 September 2025
•Electrotactile-Based Pulse Wave Reconstruction: The technology leverages electrotactile principles to mechanically reconstruct human pulse waves, enabling remote pulse diagnosis with high fidelity.•Mathematical...
Determining carbon fate and budgets throughout the Yangtze mainstream’s transportation processes
Available online 9 September 2025
It is critical to comprehensively and accurately assess large-scale river carbon (C) fluxes and budgets for reducing global C budget uncertainty, particularly in rivers where extensive dam construction...
Innovating transcranial magnetic stimulation treatment for post-traumatic stress disorder: Zapping away the bad memory
Available online 9 September 2025
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition characterized by dysregulated fear memory, emotional disturbances, and impaired cognition, driven by dysfunctions across...
Brain-wide atlas of outputs and inputs of mouse auditory cortex revealed by modified viral labeling strategies
Available online 8 September 2025
Understanding brain-wide connectivity is necessary to understand the principles of neural functions. While traditional neuron labeling methods have contributed to structural mapping, they often fall...
Novel and emerging physical treatments for major depressive disorder
Available online 8 September 2025
Major depressive disorder (MDD), a widespread psychiatric disease with significant impacts on neurological functioning and quality of life, affects 4.4% of the global population. Despite the availability...
Early detection of biodiversity degradation risks: The critical role of remote sensing
Available online 4 September 2025
The latest UN environmental report warns that the world is facing three interconnected crises: climate change, environmental pollution, and biodiversity loss. Notably, under the dual pressures of extreme...
Unveiling the 5f electron hybridization process in the antiferromagnetic heavy-fermion superconductor UPd2Al3 via ARPES and Time-resolved PES
Available online 3 September 2025
Drought facilitated the westward expansion of the Mongol Empire in the 1230s
Available online 3 September 2025
•Reconstructed summer water balance on the East European Plain from 943 to 2019 CE using tree-ring data, providing the climatic context during the Mongol Empire's western expedition.•Persistent arid...
Large-scale evidence for highly coupled soil multi-elements in permafrost ecosystems
Available online 1 September 2025
The coupled soil element cycles are the foundation of many crucial ecosystem functions such as primary production and climate regulation. However, whether and how multiple soil elements are coupled...
Harnessing multi-omics and machine learning for predicting immune checkpoint blockade responses: Advances, challenges, and future directions
Available online 31 August 2025
Immune checkpoint blockade (ICB) therapies have revolutionized cancer treatment, showing success across various cancer types. However, there is variability in response rates among different cancers...
Perovskite fluid dynamics
Available online 29 August 2025
The phase transition of perovskite thin films is inherently rapid and highly sensitive to multiple factors. Fluid dynamics has emerged as a powerful framework for elucidating the crystallization and...
Laser-printed bio-inspired constant-gradient corrugated structure with enhanced compression resistance
Available online 29 August 2025
Gradient multilayer structures can be readily created using additive manufacturing (AM) technologies and have attracted much attention in the aviation, aerospace, and automotive industries. However,...
Eco-evolutionary processes shaping Endozoicomonas associations with marine invertebrates
Available online 28 August 2025
•By integrating various hypervariable regions of 16S rRNA genes from 17,235 samples, we present a comprehensive view of Endozoicomonas biodiversity in the ocean.•Both host phylogeny and biogeography...
H4K20me3 erasure facilitates reprogramming to totipotent-like state by promoting DUX4 mediated transcription
Available online 27 August 2025
Epigenetic remodeling following fertilization is essential for the acquisition of embryonic totipotency. The role of H4K20me3, a key epigenetic modification, remains largely unexplored in the context...
A Survey on Acoustic Sensing in the Metasurface Era: Challenges, Advances, and Applications
Available online 26 August 2025
Unlike RF sensing, which relies on dedicated sensors, acoustic sensing in ubiquitous environment takes advantage of affordable microphones and speakers in Commercial-off-the-Shelf (COTS) devices—originally...
Research progress of omics technologies in forage breeding
Available online 26 August 2025
Forages are essential to global agriculture and ecosystems, with the development of high-yield, high-quality varieties as a cornerstone of efficient agricultural practices. However, traditional genetic...
Endosomes: An underappreciated player in cell signal transduction
Available online 25 August 2025
Cellular signal transduction and endocytosis represent two critical biological mechanisms that facilitate the exchange of substances and information between cells and their external environment. Conventionally,...
Graphene in photonic sensing: From fundamentals to cutting-edge applications
Available online 21 August 2025
Graphene-based photonic sensors have drawn considerable attention for their exceptional optical, electrical, and mechanical properties, enabling the development of highly sensitive, fast, and energy-efficient...
Intraoperative temporal interference (TI)-noninvasive brain stimulation prevents postoperative delirium in mice
Available online 16 August 2025
Postoperative delirium (POD), a common neurocognitive complication in the early postoperative period associated with high morbidity in elderly and high-risk surgical patients, faces fundamental research...
Mechanism-directed design and synthesis of a dinuclear copper porphyrin for efficient electrocatalytic hydrogen evolution reaction
Available online 16 August 2025
•Present mechanism-directed design and synthesis of a dinuclear Cu porphyrin for catalytic hydrogen evolution reaction.•Reveal the critical role of intramolecular electron transfer between the two Cu...
A family of multi-stable mechanisms based on the threefold-symmetric Bricard linkage
Available online 5 August 2025
Multi-stable structures capable of switching among stable states play an important role in various engineering applications. By extending the discrete stable state into a finite range of mechanism motion...
Train operational state estimation: Technologies, challenges, and future directions
Available online 5 August 2025
As the demand for intelligent transportation systems grows, train operations are becoming increasingly complex, making state estimation critical for improving railway safety and operational efficiency....
Status quo, challenges and future directions of hydrogen medicine
Available online 5 August 2025
The hydrogen molecule (H2) has distinctive characteristics and advantages in broad-spectrum anti-inflammation, high biosafety and strong tissue permeability, exhibiting therapeutic potential in numerous...
Toward Pan-Age Sepsis Detection: Leveraging Pediatric Transcriptome Data to Enhance Diagnostic Model Generalizability in Heterogeneous Populations
Available online 5 August 2025
Sepsis poses a threat to individuals across all age groups, from infants to geriatrics, due to its non-specific predisposition. Patients across different age groups demonstrate marked differences in...
