Transmission of respiratory infectious diseases based on real close contact behavior in an emergency room
December 2025
The risk of transmission of respiratory infectious diseases in emergency rooms is high, posing a severe threat to the health of healthcare workers (HCWs)....
Epidemiological impact of revoking mask-wearing recommendation on COVID-19 transmission in Tokyo, Japan
December 2024
Despite the global implementation of COVID-19 mitigation measures, the disease continues to maintain transmission. Although mask wearing became one of the key measures for preventing the transmission...
To mask or not to mask: Modeling the potential for face mask use by the general public to curtail the COVID-19 pandemic
2020
Face mask use by the general public for limiting the spread of the COVID-19 pandemic is controversial, though increasingly recommended, and the potential of this intervention is not well understood....
Global infectious disease early warning models: An updated review and lessons from the COVID-19 pandemic
June 2025
An early warning model for infectious diseases is a crucial tool for timely monitoring, prevention, and control of disease outbreaks. The integration of diverse multi-source data using big data and...
A primer on model selection using the Akaike Information Criterion
2020
A powerful investigative tool in biology is to consider not a single mathematical model but a collection of models designed to explore different working hypotheses and select the best model in that...
Origins of the problematic E in SEIR epidemic models
September 2024
During the COVID-19 pandemic, over one thousand papers were published on “Susceptible-Exposed-Infectious-Removed” (SEIR) epidemic computational models. The English word “exposed” in its vernacular and...
Mathematical modeling of malaria transmission dynamics in humans with mobility and control states
December 2023
Malaria importation is one of the hypothetical drivers of malaria transmission dynamics across the globe. Several studies on malaria importation focused on the effect of the use of conventional malaria...
Estimating epidemic exponential growth rate and basic reproduction number
2020
The initial exponential growth rate of an epidemic is an important measure of the severeness of the epidemic, and is also closely related to the basic reproduction number. Estimating the growth rate...
Impact of climate change on dengue fever epidemics in South and Southeast Asian settings: A modelling study
September 2023
The potential for dengue fever epidemic due to climate change remains uncertain in tropical areas. This study aims to assess the impact of climate change on dengue fever transmission in four South and...
Plausible explanation for the third COVID-19 wave in India and its implications
March 2023
Recently some of us used a random-walk Monte Carlo simulation approach to study the spread of COVID-19. The calculations were reasonably successful in describing secondary and tertiary waves of infection,...
A simple modification to the classical SIR model to estimate the proportion of under-reported infections using case studies in flu and COVID-19
December 2024
Under-reporting and, thus, uncertainty around the true incidence of health events is common in all public health reporting systems. While the problem of under-reporting is acknowledged in epidemiology,...
Regional variations in HIV diagnosis in Japan before and during the COVID-19 pandemic
March 2025
The number of people undergoing voluntary HIV testing has abruptly decreased since 2020. The geographical heterogeneity of HIV infection and the impact of COVID-19 on the diagnosis of HIV at regional...
Using statistics and mathematical modelling to understand infectious disease outbreaks: COVID-19 as an example
2020
During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated...
Application of multiple linear regression model and long short-term memory with compartmental model to forecast dengue cases in Selangor, Malaysia based on climate variables
March 2025
Despite the implementation of various initiatives, dengue remains a significant public health concern in Malaysia. Given that dengue has no specific treatment, dengue prediction remains a useful early...
A primer on stochastic epidemic models: Formulation, numerical simulation, and analysis
May 2017
Some mathematical methods for formulation and numerical simulation of stochastic epidemic models are presented. Specifically, models are formulated for continuous-time Markov chains and stochastic differential...
Impact of asymptomatic infections on malaria transmission dynamics
December 2025
A considerable proportion of malaria infections are asymptomatic, serving as reservoirs that sustain transmission. This study develops a deterministic mathematical model to examine the spread of malaria...
A statistical model for forecasting probabilistic epidemic bands for dengue cases in Brazil
December 2025
Dengue is a vector-borne disease and a major public health concern in Brazil. Its continuing and rising burden has led the Brazilian Ministry of Health to request for modelling efforts to aid in the...
Mathematical modeling with optimal control analysis of social media addiction
2021
In this paper, we developed a deterministic mathematical model of social media addiction (SMA) with an optimal control strategy. Major qualitative analysis like the social media addiction free equilibrium...
Predicting influenza in China from October 1, 2023, to February 5, 2024: A transmission dynamics model based on population migration
March 2025
Since November 2023, influenza has ranked first in reported cases of infectious diseases in China, with the outbreak in both northern and southern provinces exceeding the levels observed during the...
Reproduction numbers of infectious disease models
August 2017
This primer article focuses on the basic reproduction number, ℛ0, for infectious diseases, and other reproduction numbers related to ℛ0 that are useful in guiding control strategies. Beginning with...
Modeling measles transmission in adults and children: Implications to vaccination for eradication
December 2024
Despite the availability of successful vaccines, measles outbreaks have occurred frequently in recent years, presumably due to the lack of proper vaccination implementation. Moreover, measles cases...
Effectivity and efficacy probiotics for Bacterial Vaginosis treatments: Meta-analysis
December 2022
Bacterial Vaginosis (BV) is the most common cause of vaginal discharge. However, in some cases, side effects and resistance rates have been reported when antibiotics are administered. This problem has...
Influence of waning immunity on vaccination decision-making: A multi-strain epidemic model with an evolutionary approach analyzing cost and efficacy
September 2024
In this research, we introduce a comprehensive epidemiological model that accounts for multiple strains of an infectious disease and two distinct vaccination options. Vaccination stands out as the most...
Modeling the transmission dynamics and control strategies during the 2017 diphtheria outbreak in Jakarta, Indonesia
March 2026
Diphtheria has resurged globally, including in Indonesia, despite widespread vaccination since the 1970s. Knowledge gaps persist in understanding contemporary transmission drivers and effective outbreak...
Graph modelling for tracking the COVID-19 pandemic spread
2021
The modelling is widely used in determining the best strategies for the mitigation of the impact of infectious diseases. Currently, the modelling of a complex system such as the spread of COVID-19 infection...