Perfluorocarbon-based oxygen carriers: What is new in 2024?
March 2024
Perflurocarbon-based oxygen carriers (PBOC) represent a major category of artificial oxygen therapeutics. Since their initial report of potential oxygen-carrying capability half a century ago, some...
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Association between opioids use and risk of multiple cancers: A two-sample Mendelian randomization study
March 2024
Previous observational studies have investigated the possible link between opiate use and the risk of cancer. Nevertheless, there is still no solid evidence linking opioids to any particular type of...
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Effect of remimazolam on postoperative sleep quality in patients undergoing laparoscopic hysterectomy: A randomized controlled trial
March 2024
Remimazolam is a new sedative-hypnotic drug, which has been demonstrated to be safe and effective for the induction and maintenance of anesthesia, but its effects on the postoperative sleep quality...
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The impact of novel coronavirus infection on blood pressure variability in patients undergoing painless gastrointestinal endoscopy
March 2024
This study aims to examine the impact of COVID-19 infection on blood pressure variability among patients undergoing painless gastrointestinal endoscopy....
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Postoperative Sore Throat After General Anesthesia: A Narrative Review
2023
Endotracheal intubation is a common operation that provides effective mechanical ventilation under general anesthesia. Additionally, it may limit aspiration of upper airway content to the lower airways....
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Lung Protection of Mechanical Ventilation during Laparoscopic Surgery: A Systematic Review
2022
Mechanical ventilation is a means of life support for patients with acute respiratory failure, and it is also an indispensable technical method for ensuring the safety of patients during general anesthesia....
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Applications of Blood Substitutes in Transplantation Surgery: Where Are We Now?
2023
Donor organ preservation is critical to the success of transplantation surgery. Static cold storage has traditionally been used ever since the beginning of transplantation surgery. Machine perfusion...
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Recommendations on Perioperative Management and Emergency Intubation for Patients with Omicron
2023
The Chinese National Health Commission adopted the strategy of "Category B and Category B Management" for Omicron infection on January 8, 2023, which might have triggered the recent Omicron epidemic...
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Remimazolam as a Potential Alternative to Propofol for General Anesthesia: A Meta-Analysis of Randomized Controlled Trials
2023
Objective: This meta-analysis aimed to systematically review randomized controlled trials (RCTs) to evaluate whether remimazolam can be an alternative to propofol for general anesthesia....
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Effects of Dexmedetomidine on Perioperative Brain Protection in Elderly Frail Patients
2023
With the rapid growth of the elderly population and advancements in surgical and anesthesia techniques, an increasing number of elderly patients are opting for surgery. Among them, the number of frail...
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Neurotoxicity of General Anesthetics in the Developing Brain: Insight into the Glutamate and GABA Receptor Signalling
2022
Millions of infants and children undergo surgery and diagnostic procedure that require prolonged administration of anesthesia and/or sedation each year. Overwhelming evidence from animal studies suggested...
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Clinical Presentations, Treatment, and Outcomes in Patients Who Developed Malignant Hyperthermia (MH) Intraoperatively: A Case Series Study
2023
Objectives: To investigate the clinical presentations, treatment, and outcomes in a large sample of patients who developed malignant hyperthermia (MH) intraoperatively....
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Meta-Analysis of Traditional Chinese Medicine Lianhua Qingwen in the Treatment of Coronavirus Disease 2019
2023
The rapid global spread of Coronavirus disease 2019 (COVID-19) has posed a serious threat to human life and health. The efficacy of combining traditional Chinese medicine, Lianhua Qingwen, with western...
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The Mechanisms of Neuroinflammation Involved in Developmental Neurotoxicity Due to Anesthetic Exposure
2022
General anesthetic (including ketamine, nitrous oxide, propofol, isoflurane and sevoflurane) have been applied to clinic surgery widely, however sevoflurane exposure to children for several times during...
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Perspectives on Propofol Anesthesia Research
2023
Propofol is a commonly used intravenous anesthetic with a complex mechanism of action that has been extensively studied in recent years. The study of propofol has provided valuable insights into the...
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Dexmedetomidine for the Management of Postoperative Catheter-Related Bladder Discomfort: A Systematic Review and Meta-Analysis
2023
Postoperative catheter-related bladder discomfort (CRBD) is a common clinical syndrome that occurs after urinary catheterization. The aim of this systematic review and meta-analysis was to evaluate...
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Comparison of Machine Learning Models for Difficult Airway
2023
Background: The accurate prediction of difficult airway (DA) is important in ICU and general anaesthesia. Our hypothesis is that machine learning models can predict difficult tracheal intubation (DTI)...
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Investigation and Analysis of Post-traumatic Stress Disorder and Coping Style of Health-care Workers after Fighting COVID-19 in Wuhan, China
2023
Introduction: The global spread of COVID-19 is occurring at an alarming rate. Nevertheless, there appears to be insufficient attention directed towards the mental state of frontline health-care workers...
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Sedation Efficacy of Remimazolam Besylate in Elderly Patients Undergoing Non-general Anesthesia and Effects on Perioperative Cognitive Function: A Clinical Trial Protocol
2022
Background: During procedures that are not performed under general anesthesia, elderly patients often have adverse emotions such as nervousness and anxiety due to their consciousness. Sedation is frequently...
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The Effects of Dexmedetomidine on Postoperative Sleep in Elderly Patients: A Systematic Review and Meta-Analysis
2023
Background: Postoperative sleep disorders in elderly patients may increase the risk of postoperative delirium or cognitive dysfunction and delay recovery. Therefore, it is imperative to develop innovative...
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Ventricular Fibrillation during Laparoscopic Liver Resection: A Case Report
2022
Background: Laparoscopic liver resection is minimally invasive and accelerates patient recovery but anesthesia management can be challenging....
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Development of A Machine Learning Model for Predicting Unanticipated Difficult Tracheal Intubation
2022
The valid prediction of unanticipated difficult tracheal intubation (DTI) is very important in clinic anesthesia. The purpose of this study was to develop a machine learning model for predicting unanticipated...
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Perioperative Infection Control Recommendations during the SARS-CoV-2 Omicron Variant Pandemic
2023
COVID-19 significantly increased perioperative risks including mortality and complications. Currently, the Omicron variant is the dominant strain worldwide. Omicron variant is highly contagious with...
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A Case Report: Application of NMBAs Significantly Improve Oxygenation of the COVID-19 Patient
2023
The Coronavirus disease 2019 (COVID-19) pandemic is caused by the novel human coronavirus SARS-CoV-2. Major complications include pneumonia and acute respiratory distress syndrome. The development of...
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