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Most Downloaded Journal of Biosafety and Biosecurity Articles

The most downloaded articles from ScienceDirect in the last 90 days.

1. Current status and future challenges of high-level biosafety laboratories in China

September 2019
Yuan Zhiming

High-level biosafety laboratories are safe and secure platforms which integrate reliable containment, well-trained personnel, and specific biosafety manuals and practices to protect researchers from...

2. Synthetic biology: Recent progress, biosafety and biosecurity concerns, and possible solutions

March 2019
Fangzhong Wang | Weiwen Zhang

Synthetic biology is a new interdisciplinary research area that uses engineering principles as guidelines for biological investigation. With research goals to modify existing biological systems or to...

3. A brief history of the development of infectious disease prevention, control, and biosafety programs in China

March 2020
Liang Huigang | Xiang Xiaowei | Huang Cui | Ma Haixia | Yuan Zhiming

Safety of human beings has always been threatened by infectious diseases. In the process of fighting them, humans have continuously explored and researched the pathogens, transmission routes, prevention,...

4. Biosafety laboratory risk assessment

September 2019
Na Li | Lingfei Hu | Aijun Jin | Jinsong Li

Biosafety laboratory risk assessment is a dynamic and systematic work. The scope of the assessment involves evaluation of pathogenic microbial hazards, experimental activities, facilities and equipment,...

5. Biosafety and biosecurity

March 2019
Dongsheng Zhou | Hongbin Song | Jianwei Wang | Zhenjun Li | Shuai Xu | Xingzhao Ji | Xuexin Hou | Jianguo Xu

With the profound changes in the international security situation, the progression of globalization, and the continuous advancement of biotechnology, the risks and challenges posed by major infectious...

6. Deliberate release: Plague – A review

March 2020
Issmaeel Ansari | Gareth Grier | Mark Byers

Yersinia pestis is the causative agent of plague and is considered one of the most likely pathogens to be used as a bioweapon. In humans, plague is a severe clinical infection that can rapidly progress...

7. Hospital biosecurity capacitation: Analysis and recommendations for the prevention and control of COVID-19

March 2020
Hui Ma | Jiangong Zhu | Jianfei Liu | Xin Zhang | Yunxi Liu | Quansheng Yang

The outbreak of the coronavirus disease 2019 (COVID-19) in December 2019 highlighted several concerns regarding hospital biosafety capacitation in the People’s Republic of China, although the epidemic...

8. Biosafety and data quality considerations for animal experiments with highly infectious agents at ABSL-3 facilities

March 2019
Ming Guo | Yong Wang | Jinbiao Liu | Zhixiang Huang | Xiangdong Li

Animal models are crucial for the study of severe infectious diseases, which is essential for determining their pathogenesis and the development of vaccines and drugs. Animal experiments involving risk...

9. Biosecurity risk mapping and gap analysis in South East Asia

March 2020
Emily Valentin Castriciones | Viji Vijayan

In today’s globalized world where travel is commonplace, a threat in one region can easily spread throughout the whole world. It is, therefore, essential for multi-disciplinary risk assessment, risk...

11. Technology and equipment development in laser-induced fluorescence-based remote and field detection of biological aerosols

September 2019
Xin Li | Shuhai Huang | Zhenhai Sun

Nowadays, biohazard events caused by laboratory pathogen leaks and infectious disease transmission have become an increasingly important threat to human safety. The principal form of transmission of...

12. Quality management in a high-containment laboratory

March 2019
M. Hou | D.L. Song | Z.L. Shi | Z.M. Yuan

The National Biosafety Laboratory level 4 in Wuhan was accredited according to the Guo Biao (National standard) 19489:2008 standard in 2017 by the China National Accreditation Service for Conformity...

13. History of and suggestions for China’s biosafety legislation

September 2019
Huigang Liang | Xiaowei Xiang | Haixia Ma | Zhiming Yuan

Biosafety has attracted an unprecedented amount of attention from the global community as an important element in national security. All biosafety issues are related to laws and therefore must be regulated...

14. Big government: The fight against the African Swine Fever in China

March 2020
Yufeng Ding | Yanli Wang

The African Swine Fever (ASF) outbreak in China triggered a series of issues such as false drug and vaccine sales, insufficient pork supply, and panic among pig farmers. As the largest pig breeder in...

15. Aerosol containment by airflow in biosafety laboratories

March 2019
Xin Feng | Yanguo Zhang | Zhonglin Xu | Donglin Song | Guoqing Cao | Lei Liang

In this paper, the progress and research related to aerosol containment by airflow in containment environments, e.g., biosafety laboratories, are introduced from a mechanical engineering view. A good...

16. Studies on developing a safe-management standard system for Chinese biosafety laboratories

March 2019
Feng W | Haixia Ma | Amei Deng | ZongSheng C | Zhiming Y

Standardization management is one of the key prerequisites to guarantee the effective and safe functioning of high-level biosafety laboratories. Since the outbreak of SARS, increasing numbers of biosafety...

17. Establishment of the key Technical Indicators of Positive Pressure Biological Protective Clothing

September 2019
Limei Hao | Zongxing Zhang | Ying Yi | Jiancheng Qi | Yongyun Zhou | Jinhui Wu

Trying to establish the key technical indicators related to positive pressure biological protective clothing (PPBPC), providing technical support for the establishment of PPBPC standards in the fut...

18. A Survey on Biosafety Practices in Lab Personnel in 12 Selected Areas of Karachi, Pakistan

March 2019
Shafiq Ahmad | Barkat Ali | Shabnam Khan | Anum Fatima | Muhammad Saeed | Ali Asghar | Syeda Sadaf Akber | Rakhshanda Baqai | Shahana Urooj Kazmi

The objective of this study was to realize the degree of biosafety precautions and measures recorded among different Private Hospitals and Diagnostic labs personnel situated in different areas of Karachi,...

19. Safety and security in the age of synthetic biology

September 2019
James W. LeDuc | Zhiming Yuan

Synthetic biology offers great potential for benefit to society, human health and agriculture; however, it also raises new concerns about safety and security. Application of established tools of biosafety...

20. Enhancing the capabilities of biosafety laboratories through the established accreditation system: Development of the biosafety laboratory accreditation system in China

September 2019
Peijun Zhai | Rong Wang | Yongyun Zhou | Dongmei Hu | Junyan li | Yali Zhou

Accreditation is now widely used to attest for laboratory competence. Although accreditation was originally used to assess products in testing laboratories and still plays an increasingly important...

21. Networking for training Level 3/4 biosafety laboratory staff

March 2019
Yi Huang | Jicheng Huang | Han Xia | Yongxia Shi | Haixia Ma | Zhiming Yuan

Worldwide, public health systems are continually challenged by emerging and re-emerging viruses. It is therefore important that high-containment labs coordinate and communicate globally to share their...

22. Biosafety and biosecurity in the era of synthetic biology: Meeting the challenges in China and the U.S.

September 2019
Thomas Inglesby | Anita Cicero | Caitlin Rivers | Weiwen Zhang

On July 26, 2019, the workshop “Biosafety and Biosecurity in the Era of Synthetic Biology: Meeting the Challenges in China and the U.S.”, co-hosted by Johns Hopkins Center for Health Security and Tianjin...

23. A global biosafety strategy research framework with specific implications for China

September 2019
Qin Qin | Youhai Sun

With accelerating environmental change, technological development, and socio-economic globalisation, the potential for biosafety crises in many countries has intensified, and the sources of harm have...

24. Reverse microbial etiology: A research field for predicting and preventing emerging infectious diseases caused by an unknown microorganism

March 2019
Jianguo Xu

To predict, detect, prepare for, and prevent potential emerging infectious diseases caused by unknown microorganisms in the future, we have proposed the research field of reverse microbial etiology....

25. Research and development of airtight biosafety containment facility for stainless steel structures

March 2019
Zongxing Zhang | Jinhui Wu | Enlei Zhang | Siqing Zhao | Dong Wang | Ying Yi | Jiancheng Qi

Airtightness of containment structures of a high-level biosafety laboratory is a critical parameter for preventing leakage of harmful bioaerosols. The aim of this study is to investigate the sealing...

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