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Recent Smart Materials in Medicine Articles

Recently published articles from Smart Materials in Medicine.

Inorganic-polymer composite coatings for biomedical devices

2021
He-yang Li | Dan-ni Huang | Ke-feng Ren | Jian Ji

Medical coatings are now playing key roles in the practical use of biomedical devices. By fabricating coatings, the biocompatibility of the devices would be significantly improved, and their biofunctions...

Ultra-transparent slippery surface

2021
Man Zhang | Chenxi Li | Shuhou Yang | Johannes Hirte | Weifeng Zhao | Qiang Wei | Zhaolu Diao | Joachim P. Spatz | Changsheng Zhao

Endoscopes are used for diagnosis and minimally invasive treatment of the interior regions of the body. The visual fields of endoscopes, especially angioscopes, are often obscured due to the contamination...

Fmoc-amino acid-based hydrogel vehicle for delivery of amygdalin to perform neuroprotection

2021
Zhao-yu Yang | Yuan-yuan Zhong | Jun Zheng | Yilin Liu | Teng Li | En Hu | Xiao-fei Zhu | Ruo-qi Ding | Yao Wu | Yi Zhang | Tao Tang | Feng He | Shun-shun Wang | Yang Wang

Amygdalin is widely distributed in the plant kingdom. Oral delivery of amygdalin releases hydrogen cyanide upon endogenous enzymes causing potential toxic effects to humans. Here, we fabricate Fmoc-Tyr–OH–amygdalin...

High strength porous PLA gyroid scaffolds manufactured via fused deposition modeling for tissue-engineering applications

2021
Mona Alizadeh-Osgouei | Yuncang Li | Alireza Vahid | Arash Ataee | Cuie Wen

Gyroid polylactic acid (PLA) scaffolds with different unit cell sizes of 2 ​mm (G2), 2.5 ​mm (G25), and 3 ​mm (G3) were fabricated via fused deposition modeling for bone tissue engineering applications....

Mussel-inspired peptide mimicking: An emerging strategy for surface bioengineering of medical implants

2021
Xu Chen | Yiqiu Gao | Yunlong Wang | Guoqing Pan

With the massive use of medical implants (e.g., metals, polymers and ceramics) in orthopedic and cardiovascular surgery, surface biomodification of these exogenous biomaterials has caused growing concern,...

Core/shell structural ultra-small gold and amyloid peptide nanocomposites with effective bacterial surface adherence and enhanced antibacterial photothermal ablation

2021
Hanmeng Gui | Yonghai Feng | Li Qiang | Tongtong Sun | Lei Liu

The exploration of ultra-small gold nanoparticles (Au NPs) (<5 ​nm) based photothermal nanoagent is important for antibacterial photothermal therapy due to their high biosafety. However, the ultra-small...

Recent advances in surface manipulation using micro-contact printing for biomedical applications

2021
Shi Qiu | Jiawen Ji | Wei Sun | Jia Pei | Jian He | Yang Li | Jiao Jiao Li | Guocheng Wang

Surface properties are largely responsible for the biological performance of biomedical devices, suggesting the great necessity of surface modification. Micro-contact printing (μCP) is a versatile surface...

Poly(glyceryl sebacate)/silk fibroin small-diameter artificial blood vessels with good elasticity and compliance

2021
Yingmei Zhang | Yue Liu | Ziyi Jiang | Jing Wang | Zhangpeng Xu | Kai Meng | Huijing Zhao

Small-diameter artificial blood vessels do not match the compliance of the host blood vessels after transplantation, will directly affect the blood compatibility of small-diameter artificial blood vessels...

Smart and in-situ formation electrospun fibrous membrane for the control of antimicrobial efficacy

2021
Zhimei Wei | Jie Yang | Shengru Long | Gang Zhang | Xiaojun Wang

A smart poly(N-isopropyl acrylamide- N-Methylol acrylamide-acrylic acid) (PNIPAm-NMA-Ac) fibrous membrane with a dual response to thermal and pH was obtained via radical copolymerization and electrospinning...

Cellularized polymeric microarchitectures for drug screening

2021
Ying Wang | Ranjith Kumar Kankala | Shi-Bin Wang | Yu Shrike Zhang | Ai-Zheng Chen

Despite the enormous applicability, the traditional, oversimplified in vitro two-dimensional (2D) monolayer cell culture models for preclinical drug screening towards evaluating pharmacological as well...

Recent advances in nano material-based application of liver neoplasms

2021
Yuan Cao | Hong-Wu Zhang

Significant impacts have occurred around the world because of liver neoplasms, especially Hepatocellular Carcinoma(HCC). Nano material has been used in diagnosis and treatment of liver neoplasms and...

Designing HA/PEI nanoparticle composite coating on biodegradable Mg–Zn–Y-Nd alloy to direct cardiovascular cells fate

2021
Jingan Li | Shuo Wang | Yulong Sheng | Changsheng Liu | Zhonghua Xue | Peiduo Tong | Shaokang Guan

Biodegradable magnesium (Mg) alloy as a new generation of cardiovascular stent material has attracted great attention. However, the problems of excessive degradability and lack of corresponding biological...

Bio-macromolecules/modified-halloysite composite hydrogel used as multi-functional wound dressing

Available online 8 April 2021
Zhangpeng Xu | Yingjun Gao | Jingjing Li | Jingjing Dai | Shanshan Zhu | Kai Meng | Weimin Yin | Huijing Zhao

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Smartphone-based square wave voltammetry system with screen-printed graphene electrodes for norepinephrine detection

2020
Daizong Ji | Zhouyuanjing Shi | Zixiang Liu | Sze Shin Low | Jingwen Zhu | Tingkai Zhang | Zetao Chen | Xiongjie Yu | Yanli Lu | Di Lu | Qingjun Liu

In recent years, researchers have begun to develop smartphone-based electrochemical system to support healthcare services. These systems are always combined with screen-printed electrodes to perform...

Biomimetic nanoparticles as universal influenza vaccine

2020
Fengyuan Wang | Guopu Chen | Yuanjin Zhao

Pandemic virus infections pose a major public health threat globally. Much efforts have been devoted to suppress the virus, including vaccine prevention, autoimmunity enhancement, and anti-virus drugs...

Nanoparticle-based drug delivery systems for cancer therapy

2020
Yu Dang | Jianjun Guan

Nanoparticle-based drug delivery system (DDS) is considered promising for cancer treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved efficacy by: 1) increasing half-life...

Intramolecular motion-associated biomaterials for image-guided cancer surgery

2020
Chao Chen | Youhong Tang | Dan Ding

Intramolecular motion-associated biomaterials (iMAB) are developing rapidly in the field of image-guided cancer surgery by virtue of their easily regulated photophysical property. Through manipulating...

Inorganic nano-carriers based smart drug delivery systems for tumor therapy

2020
Zhaoqing Shi | Yun Zhou | Taojian Fan | Yaoxin Lin | Han Zhang | Lin Mei

Tumor is a severe disease that affects human health. In addition to surgical treatment and radiotherapy, applying therapeutic agents that can kill the tumor directly or regulate immune systems is one...

Spiky nanostructures for virus inhibition and infection prevention

2020
Chuanxiong Nie | Lang Ma | Hongrong Luo | Jinku Bao | Chong Cheng

The outbreak of a novel highly infectious virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has aroused people’s concern about public health. The lack of ready-to-use vaccines and...

Biomaterial surface modification for underwater adhesion

2020
Yue Hou | Xu Deng | Chaoming Xie

Biomaterial surfaces tend to adhere only under dry conditions, preventing them from being used in underwater environments such as body fluids. Therefore, biomaterial surfaces with underwater adhesion...

Recent progress in the development of portable high voltage source based on triboelectric nanogenerator

2020
Xingling Wang | Xiangyu Chen | Mitsumasa Iwamoto

Triboelectric nanogenerators (TENGs), which can transfer surrounding environmental mechanical stimuli into electricity effectively, could be an ideal candidate as a sustainable power supply for electrical...

Responsive principles and applications of smart materials in biosensing

2020
Zhaoyang Guo | Haiyang Liu | Wubin Dai | Yifeng Lei

Biosensing is a rising analytical field for detection of biological indicators using transducing systems. Smart materials can response to external stimuli, and translate the stimuli from biological...

Smart materials for smart healthcare– moving from sensors and actuators to self-sustained nanoenergy nanosystems

2020
Faezeh Arab Hassani | Qiongfeng Shi | Feng Wen | Tianyiyi He | Ahmed Haroun | Yanqin Yang | Yuqin Feng | Chengkuo Lee

Smart materials offer a significant role in on our lives covering various sensing and actuation applications in healthcare due to their responsivity to external stimuli such as stress, light, temperature,...

Synergic treatment of Alzheimer’s disease with brain targeted nanoparticles incorporating NgR-siRNA and brain derived neurotrophic factor

2020
Zhanwen Wang | Ying Cheng | Deqiang Zhao | Artem Pliss | Jun Liu | Ping Luan

The decrease and functional failure of the central cholinergic neurons caused by degeneration and necrosis, not only directly led to a series of clinical symptoms of Alzheimer’s disease (AD), but also...

Recent development of implantable and flexible nerve electrodes

2020
Yue Shi | Ruping Liu | Liang He | Hongqing Feng | Ye Li | Zhou Li

Implantable electrical devices offer a variety of potential diagnostic options and treatments in different medical fields. Especially in the absence of specific drugs, the implantable nerve electrodes...

Efficient integration and fast excretion of drug carrier: The trojan horse for cancer therapy

2020
Wang Zhen | Wenguo Cui

Macromolecular engineering has benefited the fabrication of drug delivery systems, owing to the versatile and tunable physical and chemical properties of the polymeric carriers as needed. However, the...

Metal-free two-dimensional nanomaterial-mediated photothermal tumor therapy

2020
Chuchu Lin | Huisong Hao | Lin Mei | Meiying Wu

The remarkable advances in nanobiotechnology have led to the rapid development of various innovative therapeutics against oncology. Two-dimensional (2D) nanomaterials with unique nanosheet structure...

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