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Most Downloaded Bioactive Materials Articles

The most downloaded articles from ScienceDirect in the last 90 days.

1. Bone grafts and biomaterials substitutes for bone defect repair: A review

December 2017
Wenhao Wang | Kelvin W.K. Yeung

Bone grafts have been predominated used to treat bone defects, delayed union or non-union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency of synthetic bone graft...

2. Photo-curing 3D printing technique and its challenges

March 2020
Haoyuan Quan | Ting Zhang | Hang Xu | Shen Luo | Jun Nie | Xiaoqun Zhu

In recent ten years, 3D printing technology has been developed rapidly. As an advanced technology, 3D printing has been used to fabricate complex and high-precision objects in many fields. 3D printing...

3. 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances

June 2018
Soroosh Derakhshanfar | Rene Mbeleck | Kaige Xu | Xingying Zhang | Wen Zhong | Malcolm Xing

3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible...

4. 3D printing of bone tissue engineering scaffolds

March 2020
Chong Wang | Wei Huang | Yu Zhou | Libing He | Zhi He | Ziling Chen | Xiao He | Shuo Tian | Jiaming Liao | Bingheng Lu | Yen Wei | Min Wang

Tissue engineering is promising in realizing successful treatments of human body tissue loss that current methods cannot treat well or achieve satisfactory clinical outcomes. In scaffold-based bone...

5. 3D bioactive composite scaffolds for bone tissue engineering

September 2018
Gareth Turnbull | Jon Clarke | Frédéric Picard | Philip Riches | Luanluan Jia | Fengxuan Han | Bin Li | Wenmiao Shu

Bone is the second most commonly transplanted tissue worldwide, with over four million operations using bone grafts or bone substitute materials annually to treat bone defects. However, significant...

6. Chitosan based bioactive materials in tissue engineering applications-A review

March 2020
Md. Minhajul Islam | Md. Shahruzzaman | Shanta Biswas | Md. Nurus Sakib | Taslim Ur Rashid

In recent years, there have been increasingly rapid advances of using bioactive materials in tissue engineering applications. Bioactive materials constitute many different structures based upon ceramic,...

7. Recent advances in periodontal regeneration: A biomaterial perspective

June 2020
Yongxi Liang | Xianghong Luan | Xiaohua Liu

Periodontal disease (PD) is one of the most common inflammatory oral diseases, affecting approximately 47% of adults aged 30 years or older in the United States. If not treated properly, PD leads to...

8. Additive manufacturing technology for porous metal implant applications and triple minimal surface structures: A review

December 2019
Li Yuan | Songlin Ding | Cuie Wen

Recently, the fabrication methods of orthopedic implants and devices have been greatly developed. Additive manufacturing technology allows the production of complex structures with bio-mimicry features,...

9. Bioactive hydrogels for bone regeneration

December 2018
Xin Bai | Mingzhu Gao | Sahla Syed | Jerry Zhuang | Xiaoyang Xu | Xue-Qing Zhang

Bone self-healing is limited and generally requires external intervention to augment bone repair and regeneration. While traditional methods for repairing bone defects such as autografts, allografts,...

10. Additive manufacturing of magnesium alloys

March 2020
Rakeshkumar Karunakaran | Sam Ortgies | Ali Tamayol | Florin Bobaru | Michael P. Sealy

Magnesium alloys are a promising new class of degradable biomaterials that have a similar stiffness to bone, which minimizes the harmful effects of stress shielding. Use of biodegradable magnesium implants...

11. Antibacterial and angiogenic chitosan microneedle array patch for promoting wound healing

June 2020
Junjie Chi | Xiaoxuan Zhang | Canwen Chen | Changmin Shao | Yuanjin Zhao | Yongan Wang

A patch with the capability of avoiding wound infection and promoting tissue remolding is of great value for wound healing. In this paper, we develop a biomass chitosan microneedle array (CSMNA) patch...

12. Recent advances in biomaterials for 3D scaffolds: A review

December 2019
Maria P. Nikolova | Murthy S. Chavali

Considering the advantages and disadvantages of biomaterials used for the production of 3D scaffolds for tissue engineering, new strategies for designing advanced functional biomimetic structures have...

13. Bioactive polymeric scaffolds for tissue engineering

December 2016
Scott Stratton | Namdev B. Shelke | Kazunori Hoshino | Swetha Rudraiah | Sangamesh G. Kumbar

A variety of engineered scaffolds have been created for tissue engineering using polymers, ceramics and their composites. Biomimicry has been adopted for majority of the three-dimensional (3D) scaffold...

14. Bioactive glass coatings on metallic implants for biomedical applications

December 2019
Joy-anne N. Oliver | Yingchao Su | Xiaonan Lu | Po-Hsuen Kuo | Jincheng Du | Donghui Zhu

Metallic implant materials possess adequate mechanical properties such as strength, elastic modulus, and ductility for long term support and stability in vivo. Traditional metallic biomaterials, including...

15. Toward dental caries: Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials

December 2019
Abdulrahman A. Balhaddad | Anmar A. Kansara | Denise Hidan | Michael D. Weir | Hockin H.K. Xu | Mary Anne S. Melo

Millions of people worldwide suffer from a toothache due to tooth cavity, and often permanent tooth loss. Dental caries, also known as tooth decay, is a biofilm-dependent infectious disease that damages...

16. A comprehensive review of biodegradable synthetic polymer-ceramic composites and their manufacture for biomedical applications

December 2019
Mona Alizadeh-Osgouei | Yuncang Li | Cuie Wen

The application of various materials in biomedical procedures has recently experienced rapid growth. One area that is currently receiving significant attention from the scientific community is the treatment...

17. Nanoparticles modified by polydopamine: Working as “drug” carriers

September 2020
Anting Jin | Yitong Wang | Kaili Lin | Lingyong Jiang

Inspired by the mechanism of mussel adhesion, polydopamine (PDA), a versatile polymer for surface modification has been discovered. Owing to its unique properties like extraordinary adhesiveness, excellent...

18. Self-assemble peptide biomaterials and their biomedical applications

December 2019
Jun Chen | Xuenong Zou

Inspired by self-assembling peptides found in native proteins, deliberately designed engineered peptides have shown outstanding biocompatibility, biodegradability, and extracellular matrix-mimicking...

19. Biomaterials for stem cell engineering and biomanufacturing

December 2019
Yibo Xu | Chuanxin Chen | Peter B. Hellwarth | Xiaoping Bao

Recent years have witnessed the expansion of tissue failures and diseases. The uprising of regenerative medicine converges the sight onto stem cell-biomaterial based therapy. Tissue engineering and...

20. Bioactive polymeric materials and electrical stimulation strategies for musculoskeletal tissue repair and regeneration

September 2020
Bryan Ferrigno | Rosalie Bordett | Nithyadevi Duraisamy | Joshua Moskow | Michael R. Arul | Swetha Rudraiah | Syam P. Nukavarapu | Anthony T. Vella | Sangamesh G. Kumbar

Electrical stimulation (ES) is predominantly used as a physical therapy modality to promote tissue healing and functional recovery. Research efforts in both laboratory and clinical settings have shown...

21. Keratin - Based materials for biomedical applications

September 2020
Sandleen Feroz | Nawshad Muhammad | Jithendra Ratnayake | George Dias

Keratin constitutes the major component of the feather, hair, hooves, horns, and wool represents a group of biological material having high cysteine content (7–13%) as compared to other structural proteins....

22. Hydrogel as a bioactive material to regulate stem cell fate

September 2016
Yung-Hao Tsou | Joe Khoneisser | Ping-Chun Huang | Xiaoyang Xu

The encapsulation of stem cells in a hydrogel substrate provides a promising future in biomedical applications. However, communications between hydrogels and stem cells is complicated; various factors...

23. The development of collagen based composite scaffolds for bone regeneration

March 2018
Dawei Zhang | Xiaowei Wu | Jingdi Chen | Kaili Lin

Bone is consisted of bone matrix, cells and bioactive factors, and bone matrix is the combination of inorganic minerals and organic polymers. Type I collagen fibril made of five triple-helical collagen...

24. Recent progress on biodegradable materials and transient electronics

September 2018
Rongfeng Li | Liu Wang | Deying Kong | Lan Yin

Transient electronics (or biodegradable electronics) is an emerging technology whose key characteristic is an ability to dissolve, resorb, or physically disappear in physiological environments in a...

25. Additive manufacturing of biodegradable porous orthopaedic screw

September 2020
Ramya Dhandapani | Priya Dharshini Krishnan | Allen Zennifer | Vishal Kannan | Amrutha Manigandan | Michael R. Arul | Devina Jaiswal | Anuradha Subramanian | Sangamesh Gurappa Kumbar | Swaminathan Sethuraman

Advent of additive manufacturing in biomedical field has nurtured fabrication of complex, customizable and reproducible orthopaedic implants. Layer-by-layer deposition of biodegradable polymer employed...

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