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Most Downloaded Bioactive Materials Articles

The most downloaded articles from ScienceDirect in the last 90 days.

1. A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light

December 2019
Bo Huang | Lei Tan | Xiangmei Liu | Jun Li | Shuilin Wu

Bone-implant materials are important for bone repairing and orthopedics surgery, which include bone plates and bone nails. These materials need to be designed not only considering its biostability and...

2. Bone grafts and biomaterials substitutes for bone defect repair: A review

December 2017
Wenhao Wang | Kelvin W.K. Yeung

Bone grafts have been predominated used to treat bone defects, delayed union or non-union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency of synthetic bone graft...

3. 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances

June 2018
Soroosh Derakhshanfar | Rene Mbeleck | Kaige Xu | Xingying Zhang | Wen Zhong | Malcolm Xing

3D printing, an additive manufacturing based technology for precise 3D construction, is currently widely employed to enhance applicability and function of cell laden scaffolds. Research on novel compatible...

4. 3D bioactive composite scaffolds for bone tissue engineering

September 2018
Gareth Turnbull | Jon Clarke | Frédéric Picard | Philip Riches | Luanluan Jia | Fengxuan Han | Bin Li | Wenmiao Shu

Bone is the second most commonly transplanted tissue worldwide, with over four million operations using bone grafts or bone substitute materials annually to treat bone defects. However, significant...

5. Additive manufacturing technology for porous metal implant applications and triple minimal surface structures: A review

December 2019
Li Yuan | Songlin Ding | Cuie Wen

Recently, the fabrication methods of orthopedic implants and devices have been greatly developed. Additive manufacturing technology allows the production of complex structures with bio-mimicry features,...

6. Toward dental caries: Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials

December 2019
Abdulrahman A. Balhaddad | Anmar A. Kansara | Denise Hidan | Michael D. Weir | Hockin H.K. Xu | Mary Anne S. Melo

Millions of people worldwide suffer from a toothache due to tooth cavity, and often permanent tooth loss. Dental caries, also known as tooth decay, is a biofilm-dependent infectious disease that damages...

7. Bioactive hydrogels for bone regeneration

December 2018
Xin Bai | Mingzhu Gao | Sahla Syed | Jerry Zhuang | Xiaoyang Xu | Xue-Qing Zhang

Bone self-healing is limited and generally requires external intervention to augment bone repair and regeneration. While traditional methods for repairing bone defects such as autografts, allografts,...

8. A comprehensive review of biodegradable synthetic polymer-ceramic composites and their manufacture for biomedical applications

December 2019
Mona Alizadeh-Osgouei | Yuncang Li | Cuie Wen

The application of various materials in biomedical procedures has recently experienced rapid growth. One area that is currently receiving significant attention from the scientific community is the treatment...

9. Latest research progress of marine microbiological corrosion and bio-fouling, and new approaches of marine anti-corrosion and anti-fouling

December 2019
Yangfan Li | Chengyun Ning

Marine resources and industry have become one of the most important pillars in economic development all over the world. However, corrosion of materials is always the most serious problem to the infrastructure...

10. Bioactive polymeric scaffolds for tissue engineering

December 2016
Scott Stratton | Namdev B. Shelke | Kazunori Hoshino | Swetha Rudraiah | Sangamesh G. Kumbar

A variety of engineered scaffolds have been created for tissue engineering using polymers, ceramics and their composites. Biomimicry has been adopted for majority of the three-dimensional (3D) scaffold...

11. Recent progress on biodegradable materials and transient electronics

September 2018
Rongfeng Li | Liu Wang | Deying Kong | Lan Yin

Transient electronics (or biodegradable electronics) is an emerging technology whose key characteristic is an ability to dissolve, resorb, or physically disappear in physiological environments in a...

12. Recent advances in biomaterials for 3D scaffolds: A review

December 2019
Maria P. Nikolova | Murthy S. Chavali

Considering the advantages and disadvantages of biomaterials used for the production of 3D scaffolds for tissue engineering, new strategies for designing advanced functional biomimetic structures have...

13. 3D printing of silk fibroin-based hybrid scaffold treated with platelet rich plasma for bone tissue engineering

December 2019
Liang Wei | Shaohua Wu | Mitchell Kuss | Xiping Jiang | Runjun Sun | Patrick Reid | Xiaohong Qin | Bin Duan

3D printing/bioprinting are promising techniques to fabricate scaffolds with well controlled and patient-specific structures and architectures for bone tissue engineering. In this study, we developed...

14. The development of collagen based composite scaffolds for bone regeneration

March 2018
Dawei Zhang | Xiaowei Wu | Jingdi Chen | Kaili Lin

Bone is consisted of bone matrix, cells and bioactive factors, and bone matrix is the combination of inorganic minerals and organic polymers. Type I collagen fibril made of five triple-helical collagen...

15. Self-assemble peptide biomaterials and their biomedical applications

December 2019
Jun Chen | Xuenong Zou

Inspired by self-assembling peptides found in native proteins, deliberately designed engineered peptides have shown outstanding biocompatibility, biodegradability, and extracellular matrix-mimicking...

16. Hydrogel as a bioactive material to regulate stem cell fate

September 2016
Yung-Hao Tsou | Joe Khoneisser | Ping-Chun Huang | Xiaoyang Xu

The encapsulation of stem cells in a hydrogel substrate provides a promising future in biomedical applications. However, communications between hydrogels and stem cells is complicated; various factors...

17. Bioactive glass coatings on metallic implants for biomedical applications

December 2019
Joy-anne N. Oliver | Yingchao Su | Xiaonan Lu | Po-Hsuen Kuo | Jincheng Du | Donghui Zhu

Metallic implant materials possess adequate mechanical properties such as strength, elastic modulus, and ductility for long term support and stability in vivo. Traditional metallic biomaterials, including...

18. Review: Bioengineering approach for the repair and regeneration of peripheral nerve

December 2019
Joshua Moskow | Bryan Ferrigno | Nikhil Mistry | Devina Jaiswal | Ketan Bulsara | Swetha Rudraiah | Sangamesh G. Kumbar

Complex craniofacial surgeries of damaged tissues have several limitations, which present complications and challenges when trying to replicate facial function and structure. Traditional treatment techniques...

19. An overview of graphene-based hydroxyapatite composites for orthopedic applications

March 2018
Ming Li | Pan Xiong | Feng Yan | Sijie Li | Changhong Ren | Zhichen Yin | Ang Li | Huafang Li | Xunming Ji | Yufeng Zheng | Yan Cheng

Hydroxyapatite (HA) is an attractive bioceramic for hard tissue repair and regeneration due to its physicochemical similarities to natural apatite. However, its low fracture toughness, poor tensile...

20. Polymeric biomaterials for biophotonic applications

December 2018
Dingying Shan | Ethan Gerhard | Chenji Zhang | John William Tierney | Daniel Xie | Zhiwen Liu | Jian Yang

With the growing importance of optical techniques in medical diagnosis and treatment, there exists a pressing need to develop and optimize materials platform for biophotonic applications. Particularly,...

21. Micro and Nanofabrication methods to control cell-substrate interactions and cell behavior: A review from the tissue engineering perspective

September 2018
Menekse Ermis | Ezgi Antmen | Vasif Hasirci

Cell-substrate interactions play a crucial role in the design of better biomaterials and integration of implants with the tissues. Adhesion is the binding process of the cells to the substrate through...

22. Enhancing cell infiltration of electrospun fibrous scaffolds in tissue regeneration

September 2016
Jinglei Wu | Yi Hong

Electrospinning is one of the most effective approaches to fabricate tissue-engineered scaffolds composed of nano-to sub-microscale fibers that simulate a native extracellular matrix. However, one major...

23. Analysis of the in vitro degradation and the in vivo tissue response to bi-layered 3D-printed scaffolds combining PLA and biphasic PLA/bioglass components – Guidance of the inflammatory response as basis for osteochondral regeneration

December 2017
Mike Barbeck | Tiziano Serra | Patrick Booms | Sanja Stojanovic | Stevo Najman | Elisabeth Engel | Robert Sader | Charles James Kirkpatrick | Melba Navarro | Shahram Ghanaati

The aim of the present study was the in vitro and in vivo analysis of a bi-layered 3D-printed scaffold combining a PLA layer and a biphasic PLA/bioglass G5 layer for regeneration of osteochondral defects...

24. Magnesium degradation under physiological conditions – Best practice

June 2018
Jorge Gonzalez | Rui Qing Hou | Eshwara P.S. Nidadavolu | Regine Willumeit-Römer | Frank Feyerabend

This review focusses on the application of physiological conditions for the mechanistic understanding of magnesium degradation. Despite the undisputed relevance of simplified laboratory setups for alloy...

25. Biofunctionalization of metallic implants by calcium phosphate coatings

December 2019
Yingchao Su | Irsalan Cockerill | Yufeng Zheng | Liping Tang | Yi-Xian Qin | Donghui Zhu

Metallic materials have been extensively applied in clinical practice due to their unique mechanical properties and durability. Recent years have witnessed broad interests and advances on surface functionalization...

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