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Most Downloaded Digital Chinese Medicine Articles

The most downloaded articles from ScienceDirect in the last 90 days.

1. Recommended Medicinal Plants as Source of Natural Products: A Review

June 2018
Henry Ivanz A. Boy | Alfred Joshua H. Rutilla | Kimbberly A. Santos | Allister Matthew T. Ty | Alicia I. Yu | Tooba Mahboob | Jitbanjong Tangpoong | Veeranoot Nissapatorn

Natural product is one of the sources of drugs in pharmaceutical industry, and one of the notable origin of natural product is the medicinal plants. Medicinal plants tend to cure some certain diseases...

2. Correlation Between Helicobacter pylori Infection and Tongue Manifestations: A Meta-analysis

June 2018
Bo-Nan HOU | Yi-Di ZENG | Hao LIANG | Rui LIU | Xiao-Qing ZHOU | Lin ZHANG | Qing-Hua PENG

Objective To analyze the relationship between Helicobacter pylori (H. pylori) infection and the manifestations of the tongue....

3. Analysis of the Phytochemistry and Bioactivity of the Genus Polygonum of Polygonaceae

March 2018
Bing-Bing Shen | Yu-Pei Yang | Sumera Yasamin | Na Liang | Wei Su | Sheng-Huang Chen | Xiao-Juan Wang | Wei Wang

The main chemical constituents of the genus Polygonum (Polygonaceae) are flavonoids, quinones, phenylpropanoids, and terpenoids, which show anticancer, antitumor, anti-oxidative, anti-inflammatory,...

4. Systems Pharmacological Approach to Investigate the Mechanism of Hericium erinaceus for Alzheimer’s Disease

March 2019
Gunter P. Eckert | Song Zhen-Yan | Cheng Shao-Wu

To confirm evidence regarding the potential therapeutic effect of Hericium erinaceus (H. erinaceus, Hou Tou Gu, 猴头菇) on Alzheimer’s disease (AD) using a system pharmacological approach in silico....

5. Lonicerae Flos: A Review of Chemical Constituents and Biological Activities

June 2018
Yan-Ran TANG | Ting ZENG | Salman zafar | Han-Wen YUAN | Bin LI | Cai-Yun PENG | Si-Cheng WANG | Yu-Qing JIAN | Yan QIN | Muhammad Iqbal Choudhary | Wei WANG

Lonicerae flos, a widely used traditional Chinese medicine (TCM), has been used for several thousand years in China. As a famous traditional Chinese herbal medicine, it was used as heat-clearing drug...

6. Design of a WeChat Learning Platform for Syndrome Differentiation

June 2018
Wen-Xiang Deng | Jian-Ping Zhu | Ying-Jiao Liu | Yi-Ge Zhang | Hui-Yong Huang | Wen-An Zhang

Objective To design a WeChat mini program called Chinese Syndrome Differentiation Learning Platform (CSDLP) on smartphone to improve health literacy....

7. Combinative Approaches of Chemistry, Pharmacology and Toxicology for the Optimal Pharmaceutical Preparation of an Anti-arthritic Chinese Medicine Formulation QFJBT

December 2018
Ting ZHANG | Huang-He YU | Ye LIN | Xin LI | Ling TAN | Hou-Pan SONG | Qing-Hua PENG | Wei WANG | Liang LIU | Cong CHEN | Xiong CAI

ObjectiveQing Fu Juan Bi Tang (QFJBT) is an anti-arthritic Chinese medicine formula consisting of five herbs: Aconiti Lateralis Radix Praeparata (Fu Zi, 附子), Sinomenii Caulis (Qing Feng Teng, 青风藤),...

8. Digital Chinese Medicine Research: an Overview

March 2018
Hui-Yong Huang | Jun-Feng Yan | Zhi-Xi Hu

Digital Chinese medicine (DCM) is an emerging interdisciplinary field developed from traditional Chinese medicine (TCM) and information science. In this article, we consider the significance and propose...

9. Dan Huang Ming Mu Recipe Suppresses the Progression of Streptozotocin-induced Diabetic Retinopathy After Retinal Laser Photocoagulation in Brown Norway Rats via Down-regulating Vascular Endothelial Growth Factor and Up-regulating Pigment Epithelium-derived Factor

March 2019
Nie Fu-Jiao | Liu Zhi-Min | Sun Shu-Ming | Yang Yi-Jing | Chen Xiang-Dong | Peng Qing-Hua

To analyze the effects of Dan Huang Ming Mu Recipe (DHMMR) (a pharmaceutical preparation from herbs and having the function of replenishing vital essence, removing heat, promoting blood circulation...

10. Advance in Studies on Chemical Constituents, Pharmacology and Quality Control of Aquilaria sinensis

December 2018
Han-Wen YUAN | Jian-Ping ZHAO | Yong-Bei LIU | Yi-Xing QIU | Qing-Ling XIE | Ming-Jiao LI | Ikhlas A. KHAN | Wei WANGb

Aquilaria sinensis (Thymelaeaceae) is widely cultivated in southern China for its significant medicinal usage. The resinous wood, the most used part of the plant as traditional Chinese medicine (TCM),...

11. Effects of Pachyman in Combination with Vinorelbine and Cisplatin on Tumor Growth and the Expression of EGFR and K-ras in Mice with Lung Cancer

December 2018
Ke WEI | Jia-Hao ZHOU | Yong-Chao CHEN | Jia-Ming TIAN | Meng-Jin SUN | Xin-Wen DAI | Bai-Hui LI | Ling LI | Fang-Liang ZHOU | Yi NING | Jue HU | Qin XIANG | Bo ZHANG | Fang-Guo LU

Objective To examine the effects of pachyman in combination with vinorelbine and cisplatin on tumor growth and the expression of epidermal growth factor receptor (EGFR) and K-ras in a mouse model of...

12. Thoughts About Paths for Digitization of Traditional Chinese Medicine - Refined Data Elements

March 2019
Zhou Xiao-Qing | Zhang Qi-Jie | Zheng Cai-Xing | Tong Tian-Hao | Yu Hao

For digitalization of traditional Chinese medicine (TCM), research is being conducted on objectivization of diagnosis and treatment, mathematical models of TCM theories, and application of modern information...

13. Effect of the Fu Zheng Method Applied by Hong-Feng CHEN on the Quality of Life in TNBC Patients and Empirical Research Based on Data Mining

December 2018
Yu-Zhu ZHANG | Yue ZHOU | Bai-Ling SHI | Hong-Feng CHEN | Li-Juan CHE

Objective To preliminarily evaluate the efficacy of the Fu Zheng method (supporting resistance against pathogenic factors) applied by Professor Hong-Feng CHEN in improving the quality of life in patients...

14. Establishing a Quality Control System of Hedyotis corymbosa

December 2018
Yan LIN | Hong-Quan LI | Bo-Hou XIA | Zhi-Min ZHANG | Ya-Mei LI | Xiao-Qing ZHANG | Ping WU | Li-Mei LIN | Duan-Fang LIAO

ObjectiveHedyotis corymbosa (Shui Xian Cao, 水线草, HC) is the main antitumor medicine in China and other southeast Asian countries. A comprehensive quality control system of HC was established in this...

15. Research on Text Mining of Syndrome Element Syndrome Differentiation by Natural Language Processing

June 2019
Deng Wen-Xiang | Zhu Jian-Ping | Li Jing | Yuan Zhi-Ying | Wu Hua-Ying | Yao Zhong- Hua | Zhang Yi-Ge | Zhang Wen-An | Huang Hui-Yong

Natural language processing (NLP) was used to excavate and visualize the core content of syndrome element syndrome differentiation (SESD)....

16. Quantitative Comparison of Bile Acid Distribution and Intestinal Transport from Native Cow-bezoar and Artificial and in vitro Cultured Substitutes using Caco-2 Cell Monolayer Model

December 2018
Ying CHEN | Xiao-Ru HU | Xian-Long CHENG | Shuang-Cheng MA | Qing-Sen RAN | Qing YANG | Wei-Jie QIANG | Zhong DAI | Xiao-Xin ZHU

Objective This study was conducted to examine the absorption and translocation of conjugated bile acids (BAs) in Calculus bovis and its substitutes to detect differences in these materials....

17. α-Glucosidase Inhibitory Activity-guided Identification of Compounds from Clerodendrum bungei Steud by HPLC-ESI- QTOF-MS/MS

March 2019
Huang Xiao-Long | Wan Dan | Shu Jun | Fang Liang-Zi | Zou Du-Zhun | Zhang Shui-Han

To identify the compounds with α-glucosidase inhibitory activity from Clerodendrum bungei Steud (Chou Mu Dan, 臭牡丹) using HPLC-ESI-QTOF-MS/MS....

18. A Review of Triterpenoids and Their Pharmacological Activities from Genus Kadsura

September 2018
Yong-Bei LIU | Yu-Pei YANG | Han-Wen YUAN | Ming-Jiao LI | Yi-Xing QIU | Muhammad Iqbal CHOUDHARY | Wei WANG

Plants in genus Kadsura, belong to the Schisandraceae family including genus Schisandra and genus Kadsura, revealed folk efficacy and medicinal application in the treatment of rheumatoid arthritis and...

19. Hub Genes of Astrocyte Involved in Glaucoma with Ocular Hypertension by Integrated Bioinformatics Analysis

December 2018
Yi-Jing YANG | Yu XIANG | Ye TIAN | Fei XIA | Ya-Sha ZHOU | Jun PENG | Qing-Hua PENG

Objective This study was conducted to elucidate the potential key candidate genes and pathways in role of astrocyte involved in glaucoma with ocular hypertension....

20. Clinical Efficacy and Therapeutic Mechanisms of Traditional Chinese Medicine for Neuroprotection and Neurogenesis in Stroke Treatment

September 2018
Jian-Gang SHEN

Stroke is the leading cause of human disability with limited effective drugs availability. The disruption of multiple signaling pathways in stroke makes developing new drugs be difficult. Traditional...

21. Optimization of Ultrasound-assisted Enzymatic Polysaccharide Extraction from Turpiniae Folium Based on Response Surface Methodology

September 2018
Ling-Jia ZHAO | Bo-Hou XIA | Li-Mei LIN | Su-Hui XIONG | Jie TANG | Duan-Fang LIAO

Objective To optimize the extraction procedure and obtain the maximum total polysaccharide yield from Turpiniae Folium....

22. Chinese Medicine in the Management of New and Emerging Infectious Diseases

March 2018
Viroj Wiwanitkit

Emerging infectious diseases are an important problem in medicine, and many continue to pose a global threat. However, the management of new and emerging infections is usually difficult due to a lack...

23. Pretreatment with Lithospermic Acid Attenuates Oxidative Stress- induced Apoptosis in Bone Marrow-derived Mesenchymal Stem Cells via Anti-oxidation and Activation of PI3K/Akt Pathway

March 2019
Li Wang-Yang | Zhou You-Liang | Li Tiao | Zeng Peng | Xu Wu-Ji | Lu Xiao-Long | Qi Xin-Yu | Xiong Hui

Despite the potential therapeutic approaches of bone marrow-derived mesenchymal stem cells (BMSCs) in orthopaedic, their applications are hampered by harsh oxidative stress conditions after transplantation....

24. Molecular Biological Mechanisms of Yuan Zhi Powder in the Treatment of Alzheimer’s Disease: an Analysis Based on Network Pharmacology

March 2018
Wei-Jie Qiang | Ying Chen | Fu-Yuan He | Mei-Feng Xiao | Wei-Yan Cai | Yi-Fei Dai | Qing Yang | Yu-Jie Li | Xiao-Gang Weng | Qi Li | Ya-Jie Wang | Xiao-Xin Zhu

Objective To predict the main active ingredients, potential targets and molecular mechanisms of Yuan Zhi powder in treatment of dementia by using network pharmacology....

25. Constitution Identification System for Traditional Chinese Medicine (TCM) Based on Correlation Between TCM Constitution and Physical Examination Indices

June 2018
Yue Luo | Bing Lin | Chuan-Biao Wen | Jie-Lin He

Objective Identification of one’s constitution based on a combination of features and back propagation neural network theory is needed in modern medicine and traditional Chinese medicine (TCM). We describe...

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