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ISSN: 2957-3912

Postoperative Sore Throat After General Anesthesia: A Narrative Review

Endotracheal intubation is a common operation that provides effective mechanical ventilation under general anesthesia. Additionally, it may limit aspiration of upper airway content to the lower airways....

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The Effects of Dexmedetomidine on Postoperative Sleep in Elderly Patients: A Systematic Review and Meta-Analysis

Background: Postoperative sleep disorders in elderly patients may increase the risk of postoperative delirium or cognitive dysfunction and delay recovery. Therefore, it is imperative to develop innovative...

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Meta-Analysis of Traditional Chinese Medicine Lianhua Qingwen in the Treatment of Coronavirus Disease 2019

The rapid global spread of Coronavirus disease 2019 (COVID-19) has posed a serious threat to human life and health. The efficacy of combining traditional Chinese medicine, Lianhua Qingwen, with western...

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Homemade Portable High-flow Nebulized Oxygen Therapy Device Used During the COVID-19 Pandemic to Improve Blood Oxygen Saturation in Critically Ill Patients: A Two-Case Report

Background: We designed a portable high-flow nebulized oxygen therapy device to temporarily provide respiratory support and maintain blood oxygen saturation for 2 elderly patients with respiratory failure...

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Sedation Efficacy of Remimazolam Besylate in Elderly Patients Undergoing Non-general Anesthesia and Effects on Perioperative Cognitive Function: A Clinical Trial Protocol

Background: During procedures that are not performed under general anesthesia, elderly patients often have adverse emotions such as nervousness and anxiety due to their consciousness. Sedation is frequently...

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Nondepolarizing Neuromuscular Blocking Agents Exacerbate Inflammation Response by Antagonizing α7 Nicotinic Acetylcholine Receptors

Studies have indicated that Nondepolarizing neuromuscular blocking agents (NMBA) can inhibit α7-nicotinic acetylcholine receptors (α7 nAChR). Our study aimed to determine whether NMBA can enhance the...

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Meglumine Cyclic Adenylate Improves Coagulation Abnormalities in Endotoxemic Rats

Background: Sepsis and endotoxemia are linked to the concurrent activation of inflammatory and hemostatic pathways, which contribute to organ dysfunction and death. Meglumine cyclic adenylate (MCA)...

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Trends in Perioperative Cardiac Output Monitoring Techniques

This article briefly reviewed the currently available techniques and commercially available monitors for the measurement of cardiac output in the management of critically ill patients and perioperative...

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The Effectiveness of Implementation of Surgical Safety Checklist in Different Countries: A Systematic Review

Background: The Surgical Safety Checklist (SSC) was created by the World Health Organization to improve patient safety and studies have shown that this checklist can significantly improve perioperative...

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Development of A Machine Learning Model for Predicting Unanticipated Difficult Tracheal Intubation

The valid prediction of unanticipated difficult tracheal intubation (DTI) is very important in clinic anesthesia. The purpose of this study was to develop a machine learning model for predicting unanticipated...

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Lung Protection of Mechanical Ventilation during Laparoscopic Surgery: A Systematic Review

Mechanical ventilation is a means of life support for patients with acute respiratory failure, and it is also an indispensable technical method for ensuring the safety of patients during general anesthesia....

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Neurotoxicity of General Anesthetics in the Developing Brain: Insight into the Glutamate and GABA Receptor Signalling

Millions of infants and children undergo surgery and diagnostic procedure that require prolonged administration of anesthesia and/or sedation each year. Overwhelming evidence from animal studies suggested...

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Development and Test of Reliability and Validity of Post Competency Evaluation Questionnaire for Specialized Anesthesia Nurses

Objective: To develop a competency evaluation questionnaire for specialized anesthesia nurses and test its reliability and validity....

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The Effect of Intravenous Injection of Lidocaine before Anesthesia Induction on Perioperative Propofol Requirement: A Meta-Analysis

Objective: Several studies have reported that intravenous lidocaine can reduce the amount of propofol but remain controversial. This study aims to quantitatively assess the effect of intravenous lidocaine...

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Ultrasound-Guided Radial Artery Cannulation Technique in Elderly Patients Undergoing Non-cardiac Surgery: A Randomized Controlled Trial

In elderly patients, radial arterial cannulation is challenging and time-consuming. With ultrasound guidance, the success rate of this procedure can be increased, the associated complications can be...

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Ventricular Fibrillation during Laparoscopic Liver Resection: A Case Report

Background: Laparoscopic liver resection is minimally invasive and accelerates patient recovery but anesthesia management can be challenging....

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Caveolin-1 Involves in the Rearrangement of F-actin through NF-κB Pathway in Endothelial Cells Induced by Lipopolysaccharide

Objective: To explore the role and possible mechanism of Caveolin-1 in the rearrangement of F-actin in endothelial cell induced by lipopolysaccharides (LPS)....

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Maternal and Infant Outcomes of Pregnancy Complicated by Pulmonary Hypertension: A Single-Center Retrospective Study from China

Background: Pulmonary hypertension (PH), a rare complication in pregnant women, is assocaited with a high maternal mortality and poor pregnancy outcomes. The purpose of this study was to retrospectively...

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The Mechanisms of Neuroinflammation Involved in Developmental Neurotoxicity Due to Anesthetic Exposure

General anesthetic (including ketamine, nitrous oxide, propofol, isoflurane and sevoflurane) have been applied to clinic surgery widely, however sevoflurane exposure to children for several times during...

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