Lipoic acid-based poly(disulfide)s: Synthesis and biomedical applications
September 2023
Biodegradable and adaptable polymeric materials are currently being studied due to their wide scope of potential applications, from nanomedicine to novel multifunctional materials. One such class of...
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Edible plant-derived extracellular vesicles serve as promising therapeutic systems
September 2023
Extracellular vesicles (EVs), which are natural nanocarriers characterized by a phospholipid bilayer structure, are released by living cells. They play a crucial role in the intercellular transport...
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Quercetin-encapsulated GelMa hydrogel microneedle reduces oxidative stress and facilitates wound healing
December 2024
Delayed wound healing brings additional physical, mental, and financial burdens. Microneedles (MNs) are a novel dressing form and can incorporate drug delivery systems. Quercetin is known for its remarkable...
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Comparative efficacy and safety of bisphosphonate therapy for bone loss in individuals after middle age: A systematic review and network meta-analysis
March 2022
PURPOSE: The purpose of this study was to estimate the benefits and drawbacks of bisphosphonates in the treatment of osteoporosis and osteopenia in middle-aged and elderly individuals....
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Profilometry and atomic force microscopy for surface characterization
March 2023
Aim: This study aims to evaluate and compare the profilometry and atomic force microscopy (AFM) for characterization of biomaterial surfaces. Method: The clinically commonly used titanium (Ti) was used...
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Tumor microenvironment responsive nanozymes for multimodal imaging of tumors
December 2024
Nanozymes exhibit immense potential and promising prospects in the realm of diagnostic imaging and tumor therapy, owing to their inherent physicochemical properties and enzymatic activities. With the...
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Advances of calcium phosphate nanoceramics for the osteoinductive potential and mechanistic pathways in maxillofacial bone defect repair
December 2024
Maxillofacial bone defects, arising from congenital malformations, tumors, infections, and traumas, represent a common clinical condition that impairs patients' appearance, speech, and motor functions....
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Biomimetic nanocarriers harnessing microbial metabolites usher the path for brain disease therapy
December 2023
The gastrointestinal system, often regarded as the 'second brain of humanity,' maintains a profound connection with the cerebral realm. Unlocking the intricate metabolic pathways of gut microorganisms...
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Bacteria-nanodrug cancer treatment system: The combination of dual swords and the confrontation of needle tips
September 2023
Cancer remains a formidable health challenge due to the limitations and toxic side effects associated with conventional treatment approaches. Recent research in the field of tumor microbiota has revealed...
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Nanodiamond in cancer theranostics
March 2023
Nanodiamonds (NDs) are emerging as a promising platform for theranostic particles since they offer a single platform that possesses multiple important properties. These include a simple mechanism of...
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The challenges to develop antibody-conjugated nanomedicine products
December 2023
Nanomedicine becomes a key player especially as next generation medicine. Antibody-conjugated nanomedicine could significantly upgrade the treatment and expand application areas. However, there are...
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Recent advances in macrophage-derived exosomes as delivery vehicles
December 2022
Macrophages are important members of the innate immune system that can be reversibly polarized by different microenvironment signals. Exosomes secreted from cells are lipid bilayer membrane vesicles...
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Application of telomere biology and telomerase in mesenchymal stem cells
December 2022
With the increasing understanding of mesenchymal stem cells (MSCs), their potential in tissue engineering and regenerative medicine has attracted more attention. However, some important problems need...
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Photothermal/photodynamic antibacterial hydrogel embedded with copper carbon dots and Au nanoparticles
December 2024
In this paper, we created a hydrogel (named AuNPs-CuCCDs@Gel) with photothermal and photodynamic performance through incorporating copper carbon dots (CuCCDs) and Au nanoparticles (AuNPs) into gelatin...
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Skin biomechanics: Breaking the dermal barriers with microneedles
March 2022
Microneedles (μND) are promising devices that can be used to transport a wide variety of active compounds into the skin. To serve as an effective delivery system, μND must pierce the human stratum corneum...
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Atomic force microscopy: A nanobiotechnology for cellular research
March 2022
Nanobiotechnology such as atomic force microscopy (AFM) has a great application in various regimes of cell biology, offering an excellent avenue to study cellular nanotopography, nanomechanics, and...
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Advances in the therapy of cerebral ischemia-reperfusion injury with natural product-based nanoparticles
December 2022
Stroke is a serious acute cerebrovascular disease attributable to disruptions in the blood supply to the brain tissue as a result of vascular obstruction or sudden rupture of blood vessels in the brain,...
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Advances in porous inorganic nanomaterials for bone regeneration
March 2022
Porous inorganic materials such as mesoporous silica nanoparticles (MSNs), mesoporous bioactive glasses (MBGs), porous calcium phosphates, and metal-organic frameworks (MOFs) are used for bone regeneration...
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Application of nanomaterials with sulfur vacancy for enhanced cancer theranostics
September 2023
Nanomaterials with excellent optical, electric, magnetic, and other physicochemical properties, are generally used in photodynamic therapy, chemodynamic therapy, and photothermal therapy of cancer....
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Nano-immunotherapy for lung cancer
March 2023
Lung cancer has the highest incidence and mortality rate worldwide. Immunotherapy is a universal treatment for lung cancer, but its overall treatment remains a challenge. Tumor immunoediting is a process...
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Advancements in modifying the efficacy of immunotherapies through the thermal effects of nanomaterials
December 2023
Tumor immunotherapy represents an intricate approach to combat tumors by modifying the immune microenvironment within the body. Nevertheless, the limited success rate and potential induction of systemic...
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Immune-mediated conditions and cellular biomarkers for early diagnosis of oral diseases
September 2023
Oral signs and symptoms are frequently the first manifestation of immunological conditions. The dentists can therefore play an important role in the detection and during the management phase of the...
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Advances in clinical detection methods and nanomaterials for autoimmune liver diseases
September 2023
Autoimmune liver disease (AILD) is a kind of chronic liver disease, due to the autoimmune tolerance of the liver break-down, as well as the imbalance of immune cell numbers and functions led to persistent...
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Ultrasound-triggerennd piezocatalytic conductive Guar gum/PEDOT: PSS/BTO composite hydrogels for bacterial-infected skin wound healing
December 2024
Open skin wounds are susceptible to infections by multidrug-resistant bacteria, which can lead to delayed wound healing or worsening of symptoms. Therefore, there is an urgent need to develop a comprehensive...
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Hyperbolic shear polaritons and their potential applications
December 2023
Hyperbolic shear polaritons recently emerge with widespread attention as a new form of polariton modes with broken symmetry due to shear lattices. Herein, the generation mechanism of hyperbolic shear...
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