Quercetin-encapsulated GelMa hydrogel microneedle reduces oxidative stress and facilitates wound healing
December 2024
Delayed wound healing brings additional physical, mental, and financial burdens. Microneedles (MNs) are a novel dressing form and can incorporate drug delivery systems. Quercetin is known for its remarkable...
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Tumor microenvironment responsive nanozymes for multimodal imaging of tumors
December 2024
Nanozymes exhibit immense potential and promising prospects in the realm of diagnostic imaging and tumor therapy, owing to their inherent physicochemical properties and enzymatic activities. With the...
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Advances of calcium phosphate nanoceramics for the osteoinductive potential and mechanistic pathways in maxillofacial bone defect repair
December 2024
Maxillofacial bone defects, arising from congenital malformations, tumors, infections, and traumas, represent a common clinical condition that impairs patients' appearance, speech, and motor functions....
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Photothermal/photodynamic antibacterial hydrogel embedded with copper carbon dots and Au nanoparticles
December 2024
In this paper, we created a hydrogel (named AuNPs-CuCCDs@Gel) with photothermal and photodynamic performance through incorporating copper carbon dots (CuCCDs) and Au nanoparticles (AuNPs) into gelatin...
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Ultrasound-triggerennd piezocatalytic conductive Guar gum/PEDOT: PSS/BTO composite hydrogels for bacterial-infected skin wound healing
December 2024
Open skin wounds are susceptible to infections by multidrug-resistant bacteria, which can lead to delayed wound healing or worsening of symptoms. Therefore, there is an urgent need to develop a comprehensive...
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Advances in clinical application of nanoparticle-based therapy for cancer treatment: A systematic review
December 2024
Due to the rapid development of nanotechnology and nanocomplex synthetic techniques, a large number of nanoparticle-based cancer medicines have been evaluated or applied in clinical trials for utility....
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Hyperbolic shear polaritons and their potential applications
December 2023
Hyperbolic shear polaritons recently emerge with widespread attention as a new form of polariton modes with broken symmetry due to shear lattices. Herein, the generation mechanism of hyperbolic shear...
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The challenges to develop antibody-conjugated nanomedicine products
December 2023
Nanomedicine becomes a key player especially as next generation medicine. Antibody-conjugated nanomedicine could significantly upgrade the treatment and expand application areas. However, there are...
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Biomimetic nanocarriers harnessing microbial metabolites usher the path for brain disease therapy
December 2023
The gastrointestinal system, often regarded as the 'second brain of humanity,' maintains a profound connection with the cerebral realm. Unlocking the intricate metabolic pathways of gut microorganisms...
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Advancements in modifying the efficacy of immunotherapies through the thermal effects of nanomaterials
December 2023
Tumor immunotherapy represents an intricate approach to combat tumors by modifying the immune microenvironment within the body. Nevertheless, the limited success rate and potential induction of systemic...
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Platelet lysate promotes proliferation and angiogenic activity of dental pulp stem cells via store-operated Ca2+ entry
December 2023
Dental pulp stem cells (DPSCs) had been widely used in nerve tissue engineering. However, the low cell survival and invalid differentiation were urgent problems to be solved for cell-based therapy....
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Immune-mediated conditions and cellular biomarkers for early diagnosis of oral diseases
September 2023
Oral signs and symptoms are frequently the first manifestation of immunological conditions. The dentists can therefore play an important role in the detection and during the management phase of the...
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Edible plant-derived extracellular vesicles serve as promising therapeutic systems
September 2023
Extracellular vesicles (EVs), which are natural nanocarriers characterized by a phospholipid bilayer structure, are released by living cells. They play a crucial role in the intercellular transport...
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Advances in clinical detection methods and nanomaterials for autoimmune liver diseases
September 2023
Autoimmune liver disease (AILD) is a kind of chronic liver disease, due to the autoimmune tolerance of the liver break-down, as well as the imbalance of immune cell numbers and functions led to persistent...
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Ferrostatin-1 loaded Gelatin methacrylate scaffold promotes recovery from spinal cord injury via inhibiting apoptosis and ferroptosis
September 2023
Spinal cord injury (SCI) is a traumatic disease that seriously damages the central nervous system, which will bring a heavy burden to patients physically, mentally and economically. Ferroptosis is a...
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GNA13 is a new marker for germinal center-derived B cell lymphomas
September 2023
We aim to evaluate the expression of GNA13 in germinal center (GC)-derived B cell lymphomas to evaluate its potential use as marker for diagnosis....
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Application of nanomaterials with sulfur vacancy for enhanced cancer theranostics
September 2023
Nanomaterials with excellent optical, electric, magnetic, and other physicochemical properties, are generally used in photodynamic therapy, chemodynamic therapy, and photothermal therapy of cancer....
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Lipoic acid-based poly(disulfide)s: Synthesis and biomedical applications
September 2023
Biodegradable and adaptable polymeric materials are currently being studied due to their wide scope of potential applications, from nanomedicine to novel multifunctional materials. One such class of...
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A brighter future for the Nano TransMed
September 2023
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Bacteria-nanodrug cancer treatment system: The combination of dual swords and the confrontation of needle tips
September 2023
Cancer remains a formidable health challenge due to the limitations and toxic side effects associated with conventional treatment approaches. Recent research in the field of tumor microbiota has revealed...
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Nanoparticle-Based Therapeutics: A Comprehensive Guide to Cancer Treatment – A book introduction
September 2023
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Associations of clinical features and dynamic immune response with the duration of viral RNA shedding in patients with COVID-19
March 2023
Background: Clinical features and the dynamic changes of the immune response in coronavirus disease-2019 (COVID-19) patients play essential roles in the disease courses. We hypothesized that clinical...
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Nano-immunotherapy for lung cancer
March 2023
Lung cancer has the highest incidence and mortality rate worldwide. Immunotherapy is a universal treatment for lung cancer, but its overall treatment remains a challenge. Tumor immunoediting is a process...
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Nanodiamond in cancer theranostics
March 2023
Nanodiamonds (NDs) are emerging as a promising platform for theranostic particles since they offer a single platform that possesses multiple important properties. These include a simple mechanism of...
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