Nomograms for predicting overall survival and cancer-specific survival of patients with stage IV renal cell carcinoma: A SEER population-based study
March 2023
Background: The purpose of this study was to explore independent favorable prognostic factors for predicting 1-, 3-, and 5-year overall survival (OS) and cancer-specific survival (CSS) in patients with...
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In-vitro physicochemical characterization of a novel type of bonedefect-filling granules—BpNcCaP in comparison to deproteinized bovine bone (Bio-Oss®)
March 2023
As alternatives to autografts, allografts, and xenografts, calcium phosphate (CaP)-based bone-defect-filling materials (e.g., deproteinized bovine bone (DBB, Bio-Oss®)) are widely used to repair large-volume...
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Profilometry and atomic force microscopy for surface characterization
March 2023
Aim: This study aims to evaluate and compare the profilometry and atomic force microscopy (AFM) for characterization of biomaterial surfaces. Method: The clinically commonly used titanium (Ti) was used...
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On nano-solutions to overcome cancer hypoxia and resistance
March 2023
Cancer is a leading cause of death globally, and current cancer therapies often fall short in reducing death and improving quality of life. Early detection of cancer cells and targeted drug application...
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A success story in these challenging times
December 2022
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Biomimetically precipitated nanocrystalline hydroxyapatite
December 2022
Nanocrystalline hydroxyapatite has been extensively used for biomedical field, such as drug carrier, antitumor agent, surface coating, and bone-regenerating material. The wet chemical method is one...
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Application of telomere biology and telomerase in mesenchymal stem cells
December 2022
With the increasing understanding of mesenchymal stem cells (MSCs), their potential in tissue engineering and regenerative medicine has attracted more attention. However, some important problems need...
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Recent advances in macrophage-derived exosomes as delivery vehicles
December 2022
Macrophages are important members of the innate immune system that can be reversibly polarized by different microenvironment signals. Exosomes secreted from cells are lipid bilayer membrane vesicles...
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Current challenges and potential directions towards nanotechnology in medicine and transformation
December 2022
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Advances in the therapy of cerebral ischemia-reperfusion injury with natural product-based nanoparticles
December 2022
Stroke is a serious acute cerebrovascular disease attributable to disruptions in the blood supply to the brain tissue as a result of vascular obstruction or sudden rupture of blood vessels in the brain,...
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Insights into the organic semiconducting photosensitizers for hypoxia-tolerant type I photodynamic therapy
December 2022
Photodynamic therapy (PDT) is a promising approach to treat cancer and microbial infections due to its minimal invasiveness, high spatiotemporal selectivity, tissue specificity, and low toxicity. Depending...
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The era of translational nanomedicine
March 2022
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Advances in porous inorganic nanomaterials for bone regeneration
March 2022
Porous inorganic materials such as mesoporous silica nanoparticles (MSNs), mesoporous bioactive glasses (MBGs), porous calcium phosphates, and metal-organic frameworks (MOFs) are used for bone regeneration...
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Skin biomechanics: Breaking the dermal barriers with microneedles
March 2022
Microneedles (μND) are promising devices that can be used to transport a wide variety of active compounds into the skin. To serve as an effective delivery system, μND must pierce the human stratum corneum...
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Evoking pyroptosis with nanomaterials for cancer immunotherapy: Current boom and novel outlook
March 2022
Cancer immunotherapy, including immune checkpoint blockade, has emerged as a powerful and effective clinical strategy for the treatment of tumors. However, the low response rates or systemic adverse...
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Atomic force microscopy: A nanobiotechnology for cellular research
March 2022
Nanobiotechnology such as atomic force microscopy (AFM) has a great application in various regimes of cell biology, offering an excellent avenue to study cellular nanotopography, nanomechanics, and...
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Comparative efficacy and safety of bisphosphonate therapy for bone loss in individuals after middle age: A systematic review and network meta-analysis
March 2022
PURPOSE: The purpose of this study was to estimate the benefits and drawbacks of bisphosphonates in the treatment of osteoporosis and osteopenia in middle-aged and elderly individuals....
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