A Reverse Micellar Peptide Nanosphere Strategy Enhancing Transdermal Delivery and Anti-Aging Performance of Palmitoyl Tripeptide-5
Available online 20 May 2026
Skin ageing is characterized by progressive extracellular matrix (ECM) degradation and reduced dermal fibroblast activity, which limit the efficacy of peptide-based cosmetic interventions. Although...
Combined microneedling and PRX PLUS for multidimensional skin quality improvement: a pilot prospective pragmatic study
Available online 15 May 2026
Microneedling and PRX PLUS formulations are established strategies for enhancing multidimensional skin quality, yet their combined use has not been systematically investigated. This pilot prospective...
Aqueous two-phase system as a greener extraction method and the synergistic effects of the herbal mixture for acne-prone skin cosmetic applications
Available online 12 May 2026
Acne-prone skin requires long-term, user-friendly cosmetic approaches that can address oxidative stress, microbial imbalance, and biofilm formation without solely relying on antibiotics....
Skin-whitening effect of Haematococcus pluvialis extract and its synergy with niacinamide
Available online 4 April 2026
Dysregulation of melanin metabolism is a primary cause of skin hyperpigmentation, making the regulation of melanin synthesis and transfer a key focus in skin-whitening research. Haematococcus pluvialis...
Spider silk applications: Dermatologic theranostics, cosmetics, aerospace, textile and electronics
March 2026
Spider silk is an exceptional biomaterial renowned for its strength, elasticity, biodegradability, and biocompatibility. Advances in recombinant DNA have enabled scalable production, broadening its...
CCN1 as an emerging key regulator in sensitive skin and skin aging: Mechanisms and therapeutic potential
March 2026
Sensitive skin and skin aging share key features such as barrier damage, chronic inflammation, extracellular matrix (ECM) breakdown, and vascular changes. Recent studies have identified Cellular Communication...
PUFECBENE®: A microencapsulated pterostilbene with enhanced bioavailability for skin depigmentation
March 2026
Pterostilbene, a bioactive compound with multifaceted therapeutic potential, has garnered significant interest in cosmetic applications for its depigmentation properties. However, its clinical utility...
Anti-photoaging effects of a topical lotion mediated by coordinated modulation of glutathione metabolism, TGF-β/Smad, and MAPK pathways for extracellular matrix homeostasis
March 2026
Skin aging results from intrinsic chronological factors and harmful environmental influences, notably photoaging characterized by UV-induced oxidative stress, which disrupts extracellular matrix (ECM)...
Enhanced skin penetration of 10-hydroxy-2-decenoic acid via anionic polymer formulations and skin hydration modulation
March 2026
The skin barrier function is primarily determined by the stratum corneum (SC), which restricts the penetration of active compounds. Royal jelly (RJ) contains 10-hydroxy-2-decenoic acid (10H2DA), an...
Quality by Design in nanotechnology applied to cosmetics: A systematic review from conception to production
March 2026
The cosmetic industry is experiencing a shift from traditional beautification to multifunctional products that combine aesthetics with scientifically validated skin health benefits. Among these advancements,...
An exploration study on the relationship between chronological and perceived age in Chinese women with systematic validation of a new method for perceived age determination
March 2026
Skin aging is a complex biological process influenced by intrinsic and extrinsic factors, leading to various aging manifestations. Defining facial aging is especially important for the selection of...
Exploring the bidirectional skin-brain axis: Mental health, dermatology-related quality of life, and the role of probiotics
March 2026
The skin–brain axis plays a key role in connecting dermatological health, mental health, and the gut microbiota. This study investigated the associations between anxiety, depression, stress, dermatology-related...
Presence of Staphylococcus aureus amplifies zinc oxide nanoparticle toxicity in skin cells
March 2026
Zinc oxide (ZnO) nanoparticles are widely used in topical products, including cosmetics and sunscreens, because of their ultraviolet-protective and antibacterial properties. Although ZnO nanoparticles...
Cosmetic applications of Nymphaea spp.: A review of extraction techniques, functional components, and efficacy mechanisms in skincare
March 2026
Nymphaea spp., possess prominent ornamental value, well-documented traditional medicinal utility, and diverse phytochemical reservoirs, making them a high-potential yet underutilized resource in cosmetic...
Applications of alpha hydroxy acids in cosmetics: A literature review
Available online 19 March 2026
Alpha-hydroxy acids (AHAs), including glycolic acid and lactobionic acid, are widely used in the treatment of various facial dermatoses. Over the past decade, these compounds have been increasingly...
Efficacy and Safety of Integrative and Complementary Treatments Versus Conventional Therapies in Patients with Vitiligo: A Systematic Review
Available online 16 March 2026
Vitiligo is a chronic depigmenting disorder with substantial psychosocial burden. Conventional therapies (topical corticosteroids, calcineurin inhibitors, phototherapy) have variable efficacy and tolerability,...
Microneedle-Based Cosmetic Delivery Systems: Advances, Applications, and Future Perspectives in Skin Care and Aesthetic Dermatology
Available online 14 March 2026
The skin’s outermost stratum corneum serves as a formidable barrier to the efficient delivery of cosmetic actives, particularly hydrophilic or high-molecular-weight compounds which often fail to penetrate...
Recent advances in synthesis and mining strategies of bioactive peptides in cosmetics
Available online 6 March 2026
Bioactive peptides have emerged as powerful functional ingredients in cosmetics, valued for their rapid action, high specificity, and low toxicity. These short amino acid sequences can deliver antimicrobial,...
Research and prospects of Anoectochilus roxburghii in the field of skin care
Available online 28 February 2026
Anoectochilus roxburghii, a homology of medicine and food, holds significant promise for skincare applications due to its bioactive components, including polysaccharides, flavonoids, and kinsenosides....
Investigation of heavy metal risks in liquid foundation products
Available online 26 February 2026
In this study, 69 batches of liquid foundation products were tested for heavy metal risk....
Exploring the soothing and reparative effects of Prinsepia utilis Royle oil based on network pharmacology and experimental validation
Available online 17 February 2026
To evaluate the soothing and reparative effects of Prinsepia utilis Royle oil in cosmetics, network pharmacology was employed to analyse the common targets of P. utilis Royle oil and skin inflammation...
Overview of clinical evaluation methods for the Soothing Efficacy of Cosmetics
Available online 28 January 2026
This review summarizes the current types of stimuli relevant to human skin, the clinical test methods for evaluating soothing efficacy, and classifies indicators based on the mechanisms of soothing...
Secukinumab in the treatment of severe plaque psoriasis during pregnancy: A case report and literature review
December 2025
A 27-year-old female patient presented with recurrent scaly erythema on the trunk and limbs accompanied by pruritus for over five years, leading to a diagnosis of severe plaque psoriasis. In 2019, the...
The impacts of non-surgical aesthetics on the core functional triad of skin
December 2025
As medical cosmetic technology advances rapidly, non-surgical aesthetics (NSA) interventions have emerged as a low-trauma and highly effective approach. It integrates traditional medical cosmetic techniques...
Bacterial cellulose as a sustainable vehicle for the controlled release of nisin and mandelic acid: A clean beauty-based approach for acne treatment
December 2025
Acne is a highly common skin condition, estimated to affect 9.4 % of the global population at some point in their lives. Today, there is a growing demand for environmentally conscious products that...