Mechanisms of tongdu tiaoshen acupuncture therapy in protecting against cerebral ischemia reperfusion injury
Available online 14 March 2026
方法 将SD大鼠随机分成假手术组,模型组,通督调神针刺组, 各12只.按Longa法制备MCAO模型, 通督调神针刺组予以针刺“大椎”,“神庭”,“百会”, 20min/次, 1次/d, 连续12 d.假手术组与模型组均在相同的针刺时间内进行抓取和固定操作, 但不给予针刺处理.采用Zea Longa法评定干预后的大鼠神经功能缺损程度, HE染色观察大鼠脑皮质病理形态改变, Western blot法检测大鼠脑皮质凋亡相关斑点样蛋白...
Broad-spectrum and eicosanoid-targeted serum lipidomics reveal the therapeutic mechanism of moxibustion in a rat model of collagen-induced arthritis
Available online 14 March 2026
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive joint destruction and high disability rates. Moxibustion, a traditional Chinese medicine therapy with a long history...
Acupuncture biomechanics: From mechanical stimulation to biological effects
Available online 14 March 2026
How acupuncture works is of significant scientific value and strategic importance in life sciences. The efficacy of acupuncture has been validated in clinic for millennia and has been widely recognized...
Research progress on the mechanism of acupuncture in treatment of ischemic stroke
Available online 12 March 2026
针刺治疗缺血性脑卒中具有多靶点,多途径的特点, 其机制涉及脑卒中的不同病理过程, 本文从炎性反应,程序性细胞死亡(凋亡,自噬,铁死亡,焦亡),氧化应激,血管新生,突触可塑性角度论述针刺治疗缺血性脑卒中的机制, 旨在为今后的研究提供一定的思考与建议....
Acupoint sensitization theory in dynamic treatment for ulcerative colitis☆
Available online 9 March 2026
Ulcerative colitis (UC) is a recurrent chronic inflammatory bowel disease and its clinical assessment relies mainly on invasive examinations with a delayed response. The acupoint sensitization theory...
Distribution characteristics of somatic hyperalgesic acupoints in patients with functional dyspepsia: A case-control study 功能性消化不良患者痛敏腧穴的分布特征:一项病例对照研究
Available online 5 March 2026
To investigate the distribution characteristics of somatic hyperalgesic acupoints in patients with functional dyspepsia (FD), at the same time, the receiver operating characteristic (ROC) curve was...
Advancing Statistical Methodologies in Traditional Chinese Medicine Research: Enhancing Statistical Transparency and Analytical Sophistication☆
Available online 4 March 2026
Traditional Chinese Medicine (TCM), with over 5,000 years of empirical practice, increasingly employs modern scientific frameworks such as randomized controlled trials (RCTs) to validate therapeutic...
Effects of transcutaneous auricular vagus nerve stimulation on the hippocampal TLR4/MyD88/NF-κB signaling pathway in rats exposed to chronic unpredictable mild stress 经皮耳迷走神经刺激对慢性不可预知温和应激大鼠海马TLR4/MyD88/NF-κB信号通路的影响
Available online 3 March 2026
Transcutaneous auricular vagus nerve stimulation (taVNS), a non-invasive neuromodulation technique, has been demonstrated to effectively treat depression and is associated with modulating stress-induced...
Acupuncture and moxibustion for chronic eczema: A systematic review 针灸治疗慢性湿疹:一项系统评价
Available online 1 March 2026
To systemically evaluate the effectiveness and safety of acupuncture and moxibustion for chronic eczema, and to provide evidence for acupuncture and moxibustion in the treatment of chronic eczema....
Multi-target synergism and integration: Mechanism of acupuncture for post-stroke cognitive impairment{cs}多靶点协同与系统整合:针刺改善脑卒中后认知障碍的机制研究
Available online 28 February 2026
脑卒中后认知障碍 (PSCI)是脑卒中后常见的致残性并发症.针刺能有效改善PSCI患者学习记忆功能, 提高患者的远期生活质量, 其机制研究也逐步从现象观察深入到多层面的作用机理探索.本文总结近年来针刺干预PSCI起效机制的相关文献, 发现针刺通过多靶点协同从而系统改善PSCI.针刺起效的机制主要是通过抑制神经炎症减轻脑内免疫损伤, 并通过增强神经可塑性来促进突触与记忆环路重建, 而调控自噬和维持神经血管单元稳定作为重要的辅助路径,...
Post-stroke electroacupuncture promotes cerebrovascular repair in the peri‑infarct cortex of ischemic stroke mice
Available online 26 February 2026
Cerebrovascular repair plays a crucial role in promoting post-stroke neurological recovery. However, effective strategies to enhance cerebrovascular repair and the underlying mechanisms remain elusive....
Overall reporting quality of acupuncture treatment for cancer-related symptoms and adverse effects of chemotherapy and radiotherapy 针刺治疗癌症相关症状及放化疗不良反应的随机对照试验报告质量评价
January 2026
The objective of this study was to systematically evaluate the reporting quality of recent randomized controlled trials (RCTs) investigating the potential of acupuncture for the management of cancer-related...
Acupuncture as an adjunctive therapy for sepsis: Advantages, limitations, and strategies 针刺辅助治疗脓毒症:优势,不足与对策
January 2026
针刺作为一种传统医学疗法, 其有效性已得到大量科学验证.近年来, 随着对针刺在炎症调节作用机制的深入研究, 针刺对脓毒症的科学研究也得到了有效的科学证实.本文探讨了针刺在脓毒症治疗中的临床效果与作用机制, 并分析了当前其作为辅助治疗手段的局限性,潜在优势与今后优化的策略.在基础研究方面, 研究人员发现针刺通过调控免疫炎症反应和自主神经系统治疗脓毒症.在临床研究方面, 多个随机对照试验结果表明,...
Moxibustion for chemotherapy-induced myelosuppression: A systematic review and meta-analysis 灸法干预化疗所致骨髓抑制:一项系统评价与Meta分析
January 2026
To evaluate the effectiveness and safety of moxibustion for chemotherapy-induced myelosuppression....
Acupoint stimulation for pain management in patients after transcatheter arterial chemoembolization: A systematic review and meta-analysis 穴位刺激改善肝动脉化疗栓塞术后患者疼痛的系统评价与Meta分析
January 2026
To systematically evaluate the clinical efficacy of acupoint stimulation for managing post-transcatheter arterial chemoembolization (TACE) pain and to provide a reliable evidence-based foundation for...
Therapeutic roles of acupuncture in the treatment of chemotherapy induced nausea and vomiting 针灸在化疗诱发性恶心与呕吐防治中的治疗作用
January 2026
Chemotherapy-induced nausea and vomiting (CINV) remains one of the most disruptive complications during cancer treatment, often persisting despite standard antiemetic regimens. As clinical practice...
Application and exploration of fNIRS in brain function mechanism of acupuncture against insomnia fNIRS技术在针刺干预失眠脑功能机制研究中的应用与探讨
January 2026
Functional near-infrared spectroscopy (fNIRS) is predominantly employed to investigate the atypical response characteristics of the cerebral cortex in neurological disorders. Recently, this technology...
Sphenopalatine ganglion stimulation: Clinical applications and innovative development 蝶腭神经节刺激技术临床应用现状及创新发展
January 2026
The sphenopalatine ganglion (SPG) is a critical parasympathetic ganglion located beneath the maxillary nerves. Its anatomical structure and function play key roles in the regulation of cerebral blood...
Advances in molecular mechanisms of acupuncture in chronic pain with depression 针刺干预慢性疼痛伴抑郁的分子机制研究进展
January 2026
Chronic pain is often accompanied by depressive emotions, and they are interacted with each other, which is one of the crucial factors to affect the clinical efficacy on pain. Acupuncture therapy has...
Key barriers and breakthrough paths for transformation of acupuncture and moxibustion device achievements 针灸设备成果转化的关键壁垒与突破路径
January 2026
As a vital component of traditional Chinese medicine (TCM), acupuncture and moxibustion face numerous challenges in the transformation of device-related achievements. This paper systematically analyzed...
Hotspots and emerging trends in acupuncture ophthalmology research: A bibliometric analysis 针灸眼科研究热点及新兴趋势: 一项文献计量学分析
January 2026
To systematically analyze the research hotspots and developmental trajectory of acupuncture ophthalmology using bibliometric methods, with the aim of clarifying research trends, collaborative networks,...
Mechanisms of tumor growth inhibition by electroacupuncture in breast cancer-bearing mice 电针抑制乳腺癌荷瘤小鼠瘤体生长的作用机制研究
October 2025
To explore the mechanism of electroacupuncture (EA) on inhibiting tumor growth in breast cancer-bearing mice....
Manual acupuncture alleviates neuronal damage condition after traumatic brain injury by inhibiting the NF-κB pathway 针刺通过抑制NF-κB通路减轻脑外伤后神经元损伤
October 2025
Acupuncture can effectively alleviate neuronal damage following traumatic brain injury (TBI); however, the underlying mechanisms remain unclear. This study aimed to investigate the putative mechanisms...
Neuroplasticicity mechanism of acupuncture for pain-induced emotions: From function to structure 针刺改善痛情绪的神经可塑性机制:从功能到结构
October 2025
Pain-induced emotions are the negative moods caused by pain, such as depression and anxiety. Acupuncture can effectively relieve pain-induced emotions, and its mechanism is closely related to the regulation...
Adrenergic agonist therapy and emerging acupuncture targets in asthma: A review of mechanisms and therapeutic implications 肾上腺素受体激动剂与针刺抗哮喘新靶标:哮喘治疗的回顾与启示
October 2025
The development of adrenergic agonists (AAs) for asthma has provided important mechanistic insights into acupuncture-based target discovery and treatment strategies. This review describes the historical...