Advancing Healthcare Through Interventional Innovation
December 2026
Dendrimer-based nanoplatforms for enhanced mRNA delivery: From rational structural design to formulation strategies
December 2026
•Dendrimer modification strategies for enhanced gene delivery are discussed.•Dendrimer-based nanoformulations boosting gene delivery are summarized.•Ionizable amphiphilic Janus dendrimers in mRNA delivery...
Conductive biomaterials for chronic wound healing
December 2026
•Reviews recent advances in conductive biomaterials for chronic wound healing, emphasizing electroactive regulation of cellular behavior and tissue regeneration.•Highlights multifunctional dressings...
Global hotspots and development trends in the new generation of artificial heart valves based on bibliometric analysis from 1991 to 2024
December 2026
•Bibliometric mapping reveals AHVs dynamic evolution (1991–2024).•Hybrid bibliometric-traditional review framework identifies future trends.•Innovation in polymer synthesis and antibacterial interfaces...
TMVP1446/GS5, a novel peptide with improved metabolic stability relative to TMVP1446, targets VEGFR-3 for primary tumor and lymph node metastases detection in vivo
December 2026
TMVP1446 is a novel peptide independently screened by our research team, which can target tumors and lymph node metastases in vivo due to its specific binding to VEGFR-3 protein. However, its poor stability...
Design and synthesis of multifunctional inorganic nanomaterials for imaging-guided photothermal therapy of tumors
December 2026
Cancer remains a formidable threat to human health and survival, underscoring the urgency of early diagnosis and effective intervention. Near-infrared (NIR) laser-induced photothermal therapy (PTT)...
Biomaterials-modulated multicellular crosstalk in 3D bioprinted constructs
December 2026
3D bioprinted scaffolds, dynamically regulated by bioactive biomaterials, have emerged as a promising strategy for tissue engineering. A major challenge of 3D bioprinted constructs lies in accurately...
Ferroptosis-triggered monodisperse microspheres for transcatheter arterial embolization of hepatocellular carcinoma
December 2026
Hepatocellular carcinoma (HCC) presents a major clinical challenge because of its high death rate and few treatment options. This study introduces an innovative therapeutic platform that combines transarterial...
Interventional hemostatic materials: innovations in bleeding control, coagulation modulation, and vascular healing
December 2026
Interventional hemostasis is essential for managing bleeding complications during minimally invasive cardiovascular procedures, yet challenges such as rapid hemostatic response, biocompatibility, and...
Progress in hepatoprotective strategies during TACE treatment
December 2026
Transarterial chemoembolization (TACE) is a cornerstone locoregional therapy for intermediate to advanced hepatocellular carcinoma and liver metastases, achieving tumor control through selective arterial...
Carrier-free zinc-baicalein nanoherbs inhibit osteosarcoma by modulating autophagy and Wnt/β-catenin pathway
December 2026
The advancement of carrier-free nanosystems offers favorable tools for achieving cancer synergistic therapy, which is attributed to their simplified preparation and simple components. Recently, traditional...
Embolic microspheres in interventional oncology and vascular therapy: Moving beyond vessel occlusion to multifunctional therapeutics
December 2026
Embolic microspheres are pivotal in interventional oncology and vascular embolization, providing targeted occlusion and therapeutic delivery with minimal systemic toxicity. Recent progress in material...
Bioengineered materials for liver fibrosis: Emerging strategies and translational challenges
December 2026
•Systematic analysis of liver fibrosis mechanisms and biomaterial design.•Advanced strategies: exosomes, nanoparticles, nanozymes with clinical cases.•Multifunctional biomaterials for microenvironment...
Attacking the “undruggable” target: The rise and evolution of targeted protein degradation technologies
December 2026
Targeted protein degradation has emerged as a powerful therapeutic paradigm that enables the selective elimination of pathogenic proteins and extends the druggable proteome beyond the reach of conventional...