#AI reads Urine# Association between urinary cesium levels and testosterone deficiency

This cross-sectional study, based on data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2011 and 2016, enrolled 2,059 adult males aged 20 years and above to explore the association between urinary cesium levels and testosterone deficiency in men. Using methods such as multivariate logistic regression, subgroup analysis, and smooth curve fitting, the study found that after adjusting for various confounding factors including age, race, and lifestyle, each unit increase in urinary cesium levels was associated with a 4% higher risk of testosterone deficiency in men. Additionally, the risk of testosterone deficiency in the group with the highest urinary cesium quartile was 42% higher than that in the lowest quartile group. A significant negative correlation was observed between urinary cesium levels and total testosterone levels, and smooth curve fitting indicated a non-linear positive correlation between urinary cesium levels and the prevalence of testosterone deficiency. Subgroup analyses confirmed the consistency of this association across different populations. The study also suggested that cesium may affect reproductive health by interfering with testosterone synthesis pathways and damaging testicular tissue, while noting limitations such as the cross-sectional design, which prevents establishing a causal relationship. Ultimately, it emphasizes the need to strengthen protective measures for individuals with occupational cesium exposure to safeguard male reproductive health.

Medicine (Baltimore). 2026 Jan 30;105(5):e46744. doi: 10.1097/MD.0000000000046744.

Youhe Gao

Statement: During the preparation of this work the author(s) used Doubao / AI reading for summarizing the content. After using this tool/service, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the published article.

For earlier AI Reads Urine articles：

https://www.keaipublishing.com/en/journals/advances-in-biomarker-sciences-and-technology/ai-reads-urine/