#AI reads Urine# Polarization-Enhanced Janus MoSSe Plasmonic Biosensor for Accurate Diabetic Nephropathy Diagnosis

This document studies a polarization-enhanced Janus MoSSe plasmonic biosensor for accurate diagnosis of diabetic nephropathy. It points out that the accurate diagnosis of diabetic nephropathy relies on the ultrasensitive detection of specific biomarkers, while existing methods have limitations such as low sensitivity and time-consuming procedures. To this end, researchers synthesized Janus MoSSe monolayers with spontaneous out-of-plane polarization via chemical vapor deposition through a heterogeneous engineering strategy. This material can enhance charge sensitivity and improve plasmonic biosensing performance, with a detection limit as low as 10⁻¹⁵ g/L for key biomarkers of diabetic nephropathy, far exceeding traditional methods such as enzyme-linked immunosorbent assay. Meanwhile, this biosensor can successfully detect a variety of related biomarkers in clinical urine samples, enabling accurate stage-specific diagnosis of diabetic nephropathy. It not only expands the application of Janus transition metal dichalcogenide monolayers but also provides a promising platform for the clinical diagnosis of diabetic nephropathy🔶.

Nano Lett. 2025 Aug 12. doi: 10.1021/acs.nanolett.5c03392

Youhe Gao

Statement: During the preparation of this work the author(s) used Doubao / AI reading for summarizing the content. After using this tool/service, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the published article.

For earlier AI Reads Urine articles：

https://www.keaipublishing.com/en/journals/advances-in-biomarker-sciences-and-technology/ai-reads-urine/