#AI reads Urine# Urine based test for acute pancreatitis diagnosis，the first pediatric study
Published 25 June, 2025
In recent decades, the incidence of pediatric acute pancreatitis has been increasing, and traditional diagnostic methods relying on serum enzyme tests are invasive and challenging for children.
The prospective study included 28 pediatric patients with 31 episodes of acute abdominal pain from November 2022 to October 2024, using INSPPIRE criteria for diagnosis. It compared the urine trypsinogen-2 dipstick test (UTDT) with serum amylase and lipase. Results showed 19 confirmed AP cases. UTDT had 68% sensitivity and 100% specificity overall, with sensitivity increasing to 87% when samples were collected within 24 hours. All non-AP cases had negative UTDT results.
The study concludes that UTDT is a promising rapid noninvasive tool, especially when used early, and may serve as an alternative to invasive blood tests, though larger studies are needed for validation.
J Pediatr Gastroenterol Nutr. 2025 Jun 17. doi: 10.1002/jpn3.70119.
The first pediatric study investigating the utility of a noninvasive urine-based test for acute pancreatitis diagnosis
Youhe Gao
Statement: During the preparation of this work the author(s) used Doubao / AI reading for summarizing the content. After using this tool/service, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the published article.
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