MedMicroEnvironment (MME) is a peer-reviewed and fully open access journal sponsored by Shandong University. The journal is dedicated to publishing rigorous, high-quality research，authoritative reviews，and forward-looking perspectives that advance our understanding of how the cellular, molecular, chemical, physical, and spatial properties of tissue microenvironments regulate physiological homeostasis, disease initiation and progression, and therapeutic response. MME aims to bridge fundamental discoveries in microenvironmental biology with translational and clinical applications.

The journal covers fundamental and translational research on medical and tissue micro environments, including but not limited to:

1. Pathological Microenvironment:

Tumour and Inflammation: Immune evasion, stromal crosstalk, and chronic inflammatory signalling.

Fibrosis and Autoimmunity: The transition from tissue repair to pathological scarring and self-attack.

Infection: Local environment factors governing pathogen survival and host response.

2. Physiological Microenvironment:

Organ-specific Physiology: Renal, Digestive, Cardiovascular, and Neuro-physiological niches.

Systemic Regulation: Metabolic, Reproduction, and Aging microenvironment.

MME also welcomes studies that use or develop advanced approaches, including single-cell and spatial omics, advanced imaging, organoids, organ-on-chip models, engineered extracellular matrices, biomaterials, and computational or systems-level methods to investigate biologically or clinically meaningful questions relating to medical microenvironments.