Role of the Glu/GABA–Gln metabolic loop in acupuncture intervention for insomnia and the progress of the study☆
Available online 23 September 2026
摘要:失眠作为常见的睡眠障碍, 其发病机制与中枢神经系统内氨基酸类神经递质失衡及代谢环路紊乱密切相关.本文系统梳理了针刺通过调节氨基酸类神经递质及代谢环路改善失眠的相关研究.总结发现, 针刺可通过调节谷氨酸(Glu),γ-氨基丁酸(GABA)等关键氨基酸类神经递质的水平, 改善神经兴奋性与抑制性的失衡状态.同时, 针刺对Glu/GABA-Gln代谢环路具有显著调控作用, 可促进Glu与Gln的循环转化,增强GABA的合成与释放,...
Effects of acupuncture at different time points on the uterine immune microenvironment in rats with primary dysmenorrhea: a mechanistic study based on regulation of the Th17/Treg balance through the IL-6/JAK2/STAT3 pathway
Available online 21 September 2026
探讨不同时机针刺对原发性痛经 (Primary dysmenorrhea, PDM) 大鼠的治疗效应及其作用机制....
Encoding and decoding of acupuncture-evoked electrical signals and their value in acupuncture–brain-computer interface-integrated closed-loop regulation
Available online 20 September 2026
针刺作为一种传统的外周刺激疗法, 其治疗效果已获得广泛的临床和生物学证据支持.从本质上讲, 针刺可被视为一种通过体表干预来调节神经功能的生物调控系统.近年来, 针刺与电信号之间的关系日益受到关注.针刺刺激能够在中枢神经系统中诱发特征性的电生理反应, 且表现出一定程度的穴位特异性和信息复杂性.与此同时, 脑机接口技术已建立起从神经电信号“读取”到“解码”的双向闭环调控框架.本综述基于电生理学的基本原理,...
Data mining of acupoint selection for post-stroke depression
Available online 18 September 2026
运用数据挖掘技术分析针灸治疗卒中后抑郁 (PSD) 的选穴规律及配伍特点, 为临床优化治疗方案提供参考依据....
Clinical efficacy of electroacupuncture at combined he-sea and front-mu points on chronic atrophic gastritis and its effects on gastric mucosal pathology: a randomized controlled exploratory trial
Available online 17 September 2026
To evaluate the clinical efficacy of electroacupuncture at combined he-sea and front-mu points combined with conventional Western medicine in treating chronic atrophic gastritis (CAG) and to observe...
Mechanism of electroacupuncture for ameliorating cytotoxic retinal edema and ganglion cell injury induced by retinal ischemia-reperfusion injury via δ-opioid receptor-mediated regulation of AQP4/Kir4.1
Available online 15 September 2026
筛选电针刺激参数, 并探讨δ-阿片受体 (DORs) 在电针抗视网膜缺血再灌注损伤 (RIRI) 所致细胞毒性视网膜水肿及视网膜神经节细胞 (RGCs) 丢失中的作用....
A longitudinal analysis of NIH funding for acupuncture-related research, 1985–2024
Available online 14 September 2026
To characterize the scope and longitudinal trends of National Institutes of Health (NIH)-funded acupuncture-related research conducted from 1985 to 2024, identify evolving research priorities and funding...
Research trends in acupuncture for obesity and metabolic syndrome: From efficacy validation to evidence building
Available online 8 September 2026
To explore the research hotspots and frontier trends in the field of acupuncture for obesity and metabolic syndrome from 2006 to 2025, thereby providing researchers with a clear understanding of the...
Knowledge graph construction and latent knowledge mining based on the Dan-an CHENG’s Acupuncture and Moxibustion Experience Collection
Available online 25 August 2026
This study employed knowledge graph (KG) construction and graph data mining techniques to systematically elucidate Dan-an CHENG’s academic experience in acupuncture diagnosis and treatment as well as...
Modern acupuncture anesthesia: From bench to bedside
Available online 9 August 2026
Acupuncture anesthesia is a product of integrating traditional Chinese medicine theory and modern western anesthesia, representing a model of integrative medicine. With the introduction of the concept...
Effects of herb-cake-separated moxibustion on colonic mast cell activation and the expression of TPSP, PAR2, PKC, and TRPV1 in the colon and spinal ganglia of rats with diarrhea-predominant irritable bowel syndrome 隔药饼灸对腹泻型肠易激综合征大鼠结肠肥大细胞活化及结肠和脊神经节中 TPSP,PAR2,PKC 和 TRPV1 表达的影响
July 2026
To investigate the potential mechanism by which herb-cake-separated moxibustion alleviates visceral hypersensitivity in rats with diarrhea-predominant irritable bowel syndrome (IBS-D), focusing on mast...
Exploration of acupuncture-moxibustion diagnosis and treatment approaches for post-stroke limb spasms based on “body and mind” theory 基于形神理论探讨卒中后肢体痉挛的针灸诊疗思路
July 2026
This paper, based on the body-mind theory, views that post-stroke limb spasticity represents a body-mind comorbidity characterized by muscular contracture. The pathogenesis includes three stages. Onset...
Acupoint-symptom quantitative analysis of acupuncture for alleviating gastrointestinal symptoms after chemotherapy for cancer 针刺改善癌症化疗后胃肠道症状的穴-症量化分析
July 2026
To define the core acupoints for improving gastrointestinal symptoms after chemotherapy, clarify their association with primary indications, and provide a scientific basis for optimizing clinical acupoint...
Scalp acupuncture for children with autism spectrum disorder: Protocol for a randomized controlled trial using EEG and structural MRI to assess multimodal neurofunctional changes
July 2026
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficits in social communication and restricted behaviors. Scalp acupuncture may improve ASD symptoms. However, high-quality...
Effectiveness and safety of Fu’s subcutaneous needling for pain: A systematic review and meta-analysis with trial sequential analysis
July 2026
To evaluate the effectiveness and safety of Fu’s subcutaneous needling (FSN) for various pain subtypes and assess the reliability of available evidence using trial sequential analysis (TSA)....
From single-target mechanisms to multi-target network regulation: Mechanisms of acupuncture in migraine
July 2026
Acupuncture has unique advantages in regulating neurotransmitters, improving vascular function, and inhibiting inflammatory responses. However, most of these studies have been limited to the independent...
Analysis of the volatile constituents from Nardostachys jatamansi DC. in combustion by HS-GC-MS and preliminary evaluation on the recycling of its dregs
July 2026
Nardostachys jatamansi (NJ) is a well-known aromatic plant whose volatile constituents hold considerable pharmacological value; it is primarily used in the form of compound herbal preparations, moxibustion...
Neuroimmune mechanism of acupuncture in regulating cancer-related symptom clusters: A research progress
July 2026
The value of acupuncture for the treatment of cancer-related symptom clusters (CRSCs) is widely recognized. The key features of its therapeutic effect on CRSCs are its holistic regulation and multitarget...
The health economics of acupuncture: Challenges and countermeasures
July 2026
Health economics evaluations of acupuncture are important and play important roles in patient decision-making, clinical decision-making, standardization of clinical practice guidelines, and policy formulation....
Bilateral sensorineural hearing loss treated with the Fameng method combined with high-frequency electroacupuncture: A case report
July 2026
This paper reports the clinical efficacy of the Fameng acupuncture method combined with high-frequency electroacupuncture in treating a case of secretory otitis media complicated by bilateral sensorineural...
Acupuncture regulation of intraocular pressure in glaucoma: Up or down
July 2026
The exact regulatory effect of acupuncture on intraocular pressure (IOP) in patients with glaucoma remains controversial. This review aimed to evaluate the current evidence regarding the effect of acupuncture...
Double-needle stratified reinforcing and reducing technique of acupuncture at the pain-sensitive points of Zusanli (ST36) and Shangjuxu (ST37) for postoperative gastroparesis: A case report
July 2026
This case report presents a 70-year-old male patient who developed gastroparesis syndrome after resection of a cancerous abdominal organ. Initially, Western medicine was used for symptomatic treatment...
Regional specificity of moxibustion in amelioration of aortic endothelial dysfunction via oxidative stress and inflammation
Available online 15 July 2026
A high-fat diet (HFD) can induce vascular endothelial dysfunction through oxidative stress and inflammatory responses. The thoracic aorta (TA) and abdominal aorta (AA) differ in anatomical structure,...
Post-stroke electroacupuncture promotes cerebrovascular repair in the peri‑infarct cortex of ischemic stroke mice 电针促进缺血性脑卒中小鼠脑血管修复作用的研究
April 2026
Cerebrovascular repair plays a crucial role in promoting post-stroke neurological recovery. However, effective strategies to enhance cerebrovascular repair and the underlying mechanisms remain elusive....
Multi-target synergism and integration: Mechanism of acupuncture for post-stroke cognitive impairment 多靶点协同与系统整合:针刺改善脑卒中后认知障碍的机制研究
April 2026
Post-stroke cognitive impairment (PSCI) is a common disabling complication after stroke. Acupuncture can effectively improve learning and memory function in patients with PSCI and enhance their quality...