Adrenergic agonist therapy and emerging acupuncture targets in asthma: A review of mechanisms and therapeutic implications
Available online 5 August 2025
肾上腺素受体激动剂治疗哮喘的发展历程, 为针灸在哮喘新靶标发现及治疗方面提供了多维度启示.本文回顾了肾上腺素受体激动剂治疗哮喘的发展历程, 包括从非选择性受体激动剂到 β2 受体激动剂的精准定位,从短效到超长效受体激动剂的效果改进,从单靶点药到靶点药物的联合使用以及剂型的改变.同时梳理了当前针灸治疗哮喘的进展, 如新型靶标药物,针灸联合用药及用药方式探索.在此基础上, 还探讨了肾上腺素受体激动剂的发展对针刺治疗哮喘的启示,...
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Inheritance and development of Lian ZHU’s acupuncture academic thought in the construction of Hospital of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences
Available online 5 August 2025
This paper exhibits the construction and development of Hospital of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences (CACMS), based on Lian ZHU’s acupuncture academic thought,...
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Neuroplasticicity mechanism of acupuncture for pain-induced emotions: From function to structure
Available online 25 July 2025
痛情绪是由疼痛诱发的抑郁,焦虑等负性情绪反应, 针刺能有效改善痛情绪, 其机制与调节神经可塑性密切相关.神经可塑性主要包括功能神经可塑性和结构神经可塑性两种类型.(1)针刺可通过抑制小胶质细胞及星形胶质细胞活化,调节神经递质及受体表达,调节细胞信号转导通路,优化突触传递效能以改善功能神经可塑性.(2)通过调节神经元突触可塑性,抑制神经细胞凋亡,上调BDNF/TrKB/CREB信号通路表达以改善结构神经可塑性.此外,...
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Mechanisms of tumor growth inhibition by electroacupuncture in breast cancer-bearing mice 电针抑制乳腺癌荷瘤小鼠瘤体生长的作用机制研究
Available online 23 July 2025
To explore the mechanism of electroacupuncture (EA) on inhibiting tumor growth in breast cancer-bearing mice....
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Manual acupuncture alleviates neuronal damage condition after traumatic brain injury by inhibiting the NF-κB pathway 针刺通过抑制NF-κB通路减轻脑外伤后神经元损伤
Available online 23 July 2025
Acupuncture can effectively alleviate neuronal damage following traumatic brain injury (TBI); however, the underlying mechanisms remain unclear. This study aimed to investigate the putative mechanisms...
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Rules of acupoint and parameter selection for electrostimulation in treatment of functional dyspepsia based on bibliometrics 基于文献计量的穴位电刺激治疗功能性消化不良取穴规律和参数选择分析
Available online 1 July 2025
To analyze the electrostimulation parameters and acupoint prescriptions for treatment of functional dyspepsia (FD) based on bibliometric methods....
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Nosocomial infections after acupuncture and related therapies: A systematic review of case reports and case series 针灸相关疗法后医院感染：病例报告和病例系列的系统回顾
Available online 21 June 2025
Acupuncture and its related therapies, as an important part of traditional Chinese medicine, have been widely accepted by the public and healthcare professionals all over the world. According to previous...
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Optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade: A data mining 基于数据挖掘技术探析近十年针灸治疗成人中心性肥胖的腧穴优选与配伍规律
Available online 20 June 2025
To explore the optimization and principles of acupoint selection and coordination in the treatment of adult abdominal obesity using acupuncture and moxibustion over the past decade using data minin...
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Effects of electroacupuncture on central insulin signal transduction-related proteins in insulin resistance model rats via the mTORC1/S6K1 pathway 基于途径探讨电针对胰岛素抵抗模型大鼠中枢胰岛素信号转导相关蛋白的影响
Available online 20 June 2025
To investigate the effects of electroacupuncture (EA) on the expression and phosphorylation of insulin signal transduction-related proteins in the hypothalamus of insulin resistance (IR) rats....
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Research progress on the mechanism of neural electrical information transmission in acupuncture intervention of depression 针刺干预抑郁障碍的神经电信息传递机制研究进展
Available online 13 June 2025
Acupuncture has been proven effective in treating depressive disorders, and its neuroelectrophysiological mechanisms have drawn increasing scientific attention. This paper reviews recent neuroelectrophysiological...
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Acupuncture-moxibustion for chemotherapy-induced peripheral neuropathy: A systematic review and network meta-analysis 针灸干预化疗致周围神经病变:一项系统评价和网状meta分析
Available online 9 June 2025
Chemotherapy-induced peripheral neuropathy (CIPN) is a common neurotoxic reaction for patients undergoing anticancer regimens. More and more studies show that acupuncture-moxibustion plays a positive...
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The analgesic effect and ATP release at acupuncture points in response to acupuncture with different parameters on arthritis rats 不同参数针刺对关节炎大鼠的镇痛作用及ATP释放的研究
Available online 9 June 2025
Previous studies indicated a close correlation between manual acupuncture (MA) analgesia and the mobilization of extracellular adenosine triphosphate (ATP) at the acupoints. This study attempted to...
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Electroacupuncture for postoperative recovery of gastrointestinal function in patients with gastrointestinal cancers: A systematic review and meta-analysis 电针促进胃肠道癌症患者术后胃肠功能恢复：一项系统评价和meta分析
Available online 7 June 2025
To evaluate the efficacy and safety of electroacupuncture (EA) for postoperative recovery in patients with gastrointestinal (GI) cancers....
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Non-pharmacological interventions for temporomandibular disorders: A systematic review and meta-analysis 非药物疗法干预颞下颌关节紊乱:一项系统评价和荟萃分析
Available online 5 June 2025
A temporomandibular disorders (TMDs) is a musculoskeletal and neuromuscular condition that affects the temporomandibular joint, masticatory muscles, and associated tissues. Non-pharmacological interventions...
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Electroacupuncture attenuates retinal ischemia/reperfusion injury by protecting the outer blood-retina barrier via enkephalins activate delta opioid receptor 电针通过脑啡肽激活δ-阿片受体保护血-视网膜外屏障以减轻视网膜缺血再灌注损伤
Available online 3 June 2025
Retinal ischemia-reperfusion (RIR) injury results in irreversible visual impairments. The disruption of the outer blood-retinal barrier (OBRB) is a major ocular pathogenic process that RIR injury affects....
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Shugan Tiaoshen needling method for postherpetic neuralgia: A randomized controlled trial 疏肝调神针刺法治疗带状疱疹后遗神经痛:一项随机对照临床试验
April 2025
To observe the efficacy of Shugan Tiaoshen (liver-soothing and mind-regulating) needling method in the treatment of patients with postherpetic neuralgia (PHN)....
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Effects of moxibustion at different temperature on wound healing and apoptosis in rats with pressure ulcer based on PI3K/AKT/mTOR signal pathway 基于PI3K/AKT/mTOR信号通路探究不同温度艾灸对压疮大鼠创面愈合及细胞凋亡的影响
April 2025
To investigate the effects of moxibustion on wound healing and evaluate whether the efficacy of moxibustion at different temperatures varies. Additionally, to explore the mechanism by which moxibustion...
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How to generate high-quality clinical evidence: Taking the study of acupuncture for chronic urticaria published in Annals of Internal Medicine as an example 高质量临床证据如何产生:以《内科学年鉴》发表的针灸治疗慢性荨麻疹研究为例
April 2025
High-quality clinical evidence is the basis of evidence-based medical practice. Acupuncture is the most widely used complementary and alternative medicine in the world. However, the improvement in the...
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Glial cell: Role of the pain modulation in acupuncture analgesia 胶质细胞：在针刺镇痛中的角色
April 2025
The significance of glial cells in the nervous system, particularly in the modulation of pain, has increasingly gained prominence, thereby shifting the traditional neurobiological research paradigm...
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Diagnosis and treatment strategy of acupuncture-moxibustion for advanced-age infertility in vitro fertilization and embryo transfer based on the temporal rhythm theory of traditional Chinese medicine 基于中医时间节律理论的高龄不孕体外受精-胚胎移植针灸诊疗思路
April 2025
The ability of natural conception decreases with age, leading many advanced-age women with fertility desire begin to attempt in vitro fertilization and embryo transfer (IVF-ET) technique nowadays. Traditional...
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Evaluation of the efficacy of electroacupuncture on pain and tolerance for unsedated colonoscopy: A study protocol for a prospective, randomized, sham-controlled trial 电针对非镇静结肠镜检查疼痛和耐受性的评估:一项前瞻性随机对照试验方案
April 2025
Unsedated colonoscopy is an important method used for diagnosing colorectal cancer, but it can cause discomfort such as pain and bloating, as well as anxiety. At present, the relief is mainly achieved...
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Mechanism of electroacupuncture on rats with primary dysmenorrhea based on microRNA expression spectrum and PI3K/Akt/mTOR signaling pathway 基于microRNA表达谱和PI3K/Akt/mTOR信号通路探讨电针干预原发性痛经大鼠机制
April 2025
To investigate the effect of electroacupuncture (EA) on microRNA (miRNA) expression spectrum and PI3K/Akt/mTOR signaling pathway in uterine tissue of rats with primary dysmenorrhea (PDM), and to explore...
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Research progress on the mechanism of acupuncture-moxibustion in promoting the rehabilitation of sequelae of ischemic stroke 针灸促进缺血性脑卒中后遗症康复机制的研究进展
April 2025
Acupuncture-moxibustion can promote recovery from the sequelae of ischemic stroke. However, its mechanism of action has not yet been fully elucidated. This paper introduces the mechanism of acupuncture-moxibustion...
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