Recent Articles

Open access

ISSN: 2790-6760
p-ISSN: 2790-7384

A mini-review on the multimodal applications of engineered magnetic nanoparticles in diagnosis and therapy

The magnetic nanoparticles (MNPs) have emerged as multifunctional tools in recent medicine by virtue of their tunable size, larger surface area, and characteristic magnetic properties. Engineered MNPs...

Next-generation injectable hydrogels: Advanced crosslinking strategies, multi-stimuli responsiveness, and translational advances for precision regenerative medicine

Injectable hydrogels represent a transformative platform in biomaterials, enabling minimally invasive delivery and precise therapeutic localization with biomimetic structural and functional properties....

SNEDDS delivery of black sticky rice extract: Hepatoprotective and antioxidant potential

Black sticky rice (Oryza sativa var. glutinosa Blanco) Extract (BSRE) contains a high concentration of polyphenols, flavonoids, and anthocyanins with known antioxidant and hepatoprotective effects....

Synergistic activity of photoactivated curcumin-derived nanocomplexes in combination with antibiotics against planktonic and biofilm bacterial cells

Alternative antimicrobial strategies such as antimicrobial photodynamic therapy (aPDT) and curcumin-derived nanocomplexes were assessed in this study against biofilm cells of Gram-positive and Gram-negative...

Curcumin poly D-L lactide nanoparticles demonstrate superior antiplasmodial Efficacy and multi-target binding compared with dihydroartemisinin: Integrative in vivo and in silico analyses

The urgent rise of drug-resistant malaria underscores the need for innovative antimalarial agents with multi-targeting capabilities. Curcumin, a polyphenolic compound derived from turmeric, is known...

Nanoparticle-Mediated Cardiotoxicity and Nanomedicine Interventions in Cancer Treatment

Nanoparticle-based therapies have emerged as transformative tools in oncology, offering targeted drug delivery, improved pharmacokinetics, and minimised systemic toxicity. However, accumulating evidence...

Nanocarriers in skin cancer treatment: Emerging drug delivery approaches and innovations

Skin cancer is a growing global health issue, with rising incidence rates, particularly among Caucasian populations. It is the most common malignancy, contributing significantly to mortality and decreased...

Nano delivery systems in stem cell therapy: Transforming regenerative medicine and overcoming clinical challenges

Stem cell therapy has emerged as a promising approach in regenerative medicine, offering potential treatments for various degenerative diseases and injuries. However, the clinical application of stem...

Antioxidant and anti-diabetic potential of the green synthesized silver nanoparticles using Martynia annua L. root extract

The weed Martynia annua traditionally known as Kakanasika is annual herbaceous plant known for its multiple medicinal properties such as anthelmintic, analgesic, antipyretic, antibacterial, anti-convulsant,...

PROTAC-based therapeutics for targeting HPV oncoproteins in head and neck cancers

The increasing incidence of Human Papillomavirus (HPV)-related head and neck cancers, particularly oropharyngeal squamous cell carcinomas, highlights the need for advanced therapeutic options beyond...

Graphene nanomaterial-based electrochemical biosensors for salivary biomarker detection: A translational approach to oral cancer diagnostics

Graphene-based electrochemical biosensors have emerged as promising tools for the early detection and monitoring of oral cancer through salivary biomarker analysis. Graphene's exceptional properties,...

Harnessing silica nanoparticles grafted with ascorbic acid to alleviate oxidative stress and impaired brain activity in rats

The brain has natural antioxidant defense systems, functioning through enzymes such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase, which neutralize reactive oxygen species...

Bio-nanomaterials: Promising anticancer properties and treatment strategies

One of the most difficult diseases to treat in people is cancer, and its mortality rate has recently increased significantly. Nanoparticles are used in the rapidly developing field of cancer nanomedicine...

Harnessing nanoparticle technology for precision medicine in head and neck cancer: Targeted delivery, immunomodulation, and clinical translation

Head and neck cancer (HNC) remains a significant challenge in oncology due to poor drug delivery and an immunosuppressive tumour microenvironment (TME). This review focuses on the role of nanoparticles...

The delivery and transmembrane transport mechanism of SVCV nanovaccine

Spring viremia of carp virus (SVCV) is a fatal microorganism for a variety of cyprinid fish species, sparking off enormous economic losses in freshwater fish aquaculture. For alleviating losses, immersion...

Recent advances in electrochemical biosensors for bacterial detection

Accurate and efficient bacterial detection remains a critical challenge in clinical diagnostics and public health. Conventional methods are often constrained by low sensitivity and labor-intensive workflows....

Application and recent progress of MXene-based bioactive materials in wound management

Wound management is one of the major challenges in the biomedical field, where wound ulceration and bacterial infections cause systemic inflammatory reactions or scarring in patients, seriously affecting...

Eco-friendly nanoparticle phytosynthesis via plant extracts: Mechanistic insights, recent advances, and multifaceted uses

This review explores the phytosynthesis of nanoparticles (NPs) using plant extracts, emphasizing mechanistic insights, recent advancements, and their diverse applications. The green and cost-effective...

Liposome-encapsulated therapies: Precision medicine for inflammatory lung disorders

Liposomes have emerged as the preferred choice over other nanocomposites for transporting a wide range of hydrophobic and hydrophilic compounds with therapeutic potential. This is primarily due to their...

Boron delivery agents in BNCT: A mini review of current developments and emerging trends

Boron Neutron Capture Therapy (BNCT) is a highly targeted form of radiation therapy offering significant potential for treating hard-to-manage cancers such as glioblastoma, head and neck cancer, and...

Nanoparticles for drug delivery: Insight into in vitro and in vivo drug release from nanomedicines

Nanotechnology enables the achievement of the desired outcomes of nano-formulations, and the mode of drug delivery from the nanoparticles can significantly impact the efficacy of the embedded drug....

Plant-based nanotherapeutics: A new frontier in disease management and prevention

Nanotechnology has emerged as a transformative force in the field of medicine, offering innovative solutions for the diagnosis, treatment, and prevention of diseases. Among the myriad sources of nanomaterials,...

Selenium, silver, and gold nanoparticles: Emerging strategies for hepatic oxidative stress and inflammation reduction

Liver failure, primarily driven by oxidative stress and inflammation, remains a significant clinical challenge. Conventional hepatoprotective strategies often fail to provide effective long-term protection,...

Liquid biopsy based on EV biomarkers: A new frontier for early diagnosis and prognosis assessment of cancer at ESMO 2024

Extracellular vesicles (EVs) are emerging as powerful biomarkers in liquid biopsy, offering insights into early cancer diagnosis, precision treatment, and prognosis evaluation. EVs, including microvesicles,...

Mitigating oxidative stress toxicities of environmental pollutants by antioxidant nanoformulations

Oxidative stress arising from reactive oxygen and nitrogen species (RONS) imposes a severe threat to living organisms by causing extensive cellular and subcellular damage. Environmental pollutants (e.g.,...

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