Mitigating oxidative stress toxicities of environmental pollutants by antioxidant nanoformulations
December 2025
Oxidative stress arising from reactive oxygen and nitrogen species (RONS) imposes a severe threat to living organisms by causing extensive cellular and subcellular damage. Environmental pollutants (e.g.,...
Redox-sensitive camptothecin prodrug: A promising drug delivery strategy with ultrahigh drug loading and tunable drug release
December 2025
Small molecular drugs play a critical role in cancer therapy but face challenges like poor solubility, severe side effects, and inefficient delivery. Polymeric micellar-based drug delivery systems show...
“Green” gas-generation strategy to combine cancer phototherapy for remarkably enhanced efficacy
December 2025
Phototherapy, which mainly includes photodynamic therapy (PDT) and photothermal therapy (PTT), has made considerable progress in the field of cancer treatment by generating reactive oxygen species or...
In-silico strategies in nano-drug design: Bridging nanomaterials and pharmacological applications
December 2025
Rapid advancements in nanotechnology have transformed drug design and delivery systems, allowing for precise and efficient therapeutic interventions. This review examines the transformative role of...
Tumor microenvironment-responsive nanoplatforms for enhanced cancer immunotherapy: Advances and synergistic strategies
December 2025
Despite remarkable advancements in cancer immunotherapy, its clinical efficacy remains constrained by challenges including insufficient tumor accumulation of immunotherapeutics, limited patient response...
Nanocarrier-based insulin delivery: A leap towards a needle-free future
December 2025
The burden of diabetes mellitus continues to escalate globally, demanding innovative and patient-centric therapeutic alternatives to conventional insulin injections. Nanocarrier-based drug delivery...
The anticancer, antioxidant, and antimicrobial properties of zinc oxide nanoparticles: A comprehensive review
December 2025
This review provides a comprehensive analysis of Zinc Oxide Nanoparticles (ZnO NPs) in biomedical applications, focusing on their anticancer, antioxidant, and antimicrobial properties. ZnO NPs, distinguished...
Integration of graphene quantum dots with 3D scaffolds for precision medicine and regenerative applications
December 2025
Integrated onto three-dimensional (3D) scaffolds, graphene quantum dots (GQDs) present a novel method for tissue creation and precision drug delivery. Among its special characteristics are photoluminescence,...
Electrospun based functional scaffolds for biomedical engineering: A review
December 2025
Tissue engineering (TE) has made significant strides and progress in the development of functional biomaterials. Among different techniques that has been adopted, electrospinning is a versatile and...
Nanocuproptosis for precision tumor immunotherapy
Available online 27 September 2025
Cuproptosis, a recently identified copper-dependent form of regulated cell death, has emerged as a promising tumor therapy owing to its unique metabolic dependence and ability to overcome resistance...
Exosomes: A next-generation cancer theranostics
Available online 11 September 2025
Quercetin-encapsulated GelMa hydrogel microneedle reduces oxidative stress and facilitates wound healing
December 2024
Delayed wound healing brings additional physical, mental, and financial burdens. Microneedles (MNs) are a novel dressing form and can incorporate drug delivery systems. Quercetin is known for its remarkable...
Photothermal/photodynamic antibacterial hydrogel embedded with copper carbon dots and Au nanoparticles
December 2024
In this paper, we created a hydrogel (named AuNPs-CuCCDs@Gel) with photothermal and photodynamic performance through incorporating copper carbon dots (CuCCDs) and Au nanoparticles (AuNPs) into gelatin...
Advances in clinical application of nanoparticle-based therapy for cancer treatment: A systematic review
December 2024
Due to the rapid development of nanotechnology and nanocomplex synthetic techniques, a large number of nanoparticle-based cancer medicines have been evaluated or applied in clinical trials for utility....
Establishment and application of a brain cell line derived from Plectropomus leopardus
December 2024
Plectropomus leopardus is an economically valuable marine farmed fish. However, diseases have seriously restricted the healthy development of its breeding industry. Cell line is an important in vitro...
Microbots: Transforming the treatment of oral cancer
December 2024
Oral cancer incidence and mortality are high in India, Papua New Guinea, Taiwan, China, Eastern Europe, France, and parts of South America, where alcohol consumption and tobacco smoking are prevalent....
Two-dimensional nano-biomaterials in regulating the tumor microenvironment for immunotherapy
December 2024
Two-dimensional (2D) nanomaterials, characterized by their ultrathin profile and constructed from single or a few atomic layers, exhibit unique physical and chemical properties. These materials have...
Exploring the denaturations in cancer and non-cancer DNA molecules by optical absorption, thermal, and electric measurements: A case study
December 2024
In this article, we carried out the temperature dependent UV-Visible (UV-Vis) spectroscopy, differential scanning calorimetry (DSC), and electrical studies for normal and cancerous (glioma) DNA samples...
Phytomedicine meets nanotechnology: A cellular approach to rheumatoid arthritis treatment
December 2024
Rheumatoid arthritis (RA) is an autoimmune condition causing synovitis, joint dysfunction, and tissue deterioration. This review highlights the pathophysiology of RA, including the involvement of cellular...
Biogenic silver nanoparticles from Simarouba glauca DC leaf extract: Synthesis, characterization, and anticancer efficacy in lung cancer cells with protective effects in Caenorhabditis elegans
December 2024
This study explores the synthesis, characterization, and biomedical applications of silver nanoparticles (AgNPs) synthesized using Simarouba glauca leaf extract. The biogenic AgNPs were characterized...