Virulence factors in biofilm formation and therapeutic strategies for Staphylococcus aureus: A review
June 2025
Staphylococcus aureus (S. aureus) is a significant human pathogen known for its ability to form biofilms, which increase its resistance to antibiotics and immune defenses. This review delves into the...
A comprehensive review of tick-borne disease epidemiology, clinical manifestations, pathogenesis, and prevention
Available online 21 May 2025
Ticks are arthropod vectors that transmit pathogens by biting and bloodsucking, and they have been found to carry or transmit over one hundred types of pathogens. The majority of these pathogens are...
Experimental animal models for urolithiasis (kidney stone): A comprehensive review
Available online 7 March 2025
Experimental animal models play a crucial role in scientific research in different fields such as medicine, biology and pharmacology. Animal models help to understanding human physiology and pathology...
Prevalence of zoonotic diseases in the Northeastern region, one health perspective
June 2025
Zoonotic diseases are long known for their disease transmission from animals to human beings or from human beings to animals. These illnesses are primarily spread by the ingestion of contaminated food...
Progress in the molecular epidemiology of chikungunya virus
June 2025
In recent years, with the global climate warming up, Aedes albopictus and Aedes aegypti have gradually expanded their range of activities from the tropics to subtropical and temperate regions, which...
Advances in endometrial receptivity and embryo implantation by multi-omics techniques
Available online 19 May 2025
Endometrial receptivity is a critical determinant of successful embryo implantation, yet current clinical assessments (e.g., ultrasound, hysteroscopy) primarily focus on morphological evaluation and...
Pathogens infected or carried by exotic pets pose emerging threat to human health
June 2025
Exotic pets refer to a variety of uncommon pets that are different from traditional pets such as cats, dogs, birds and fish. Due to the convenience of international travel, the diversity and globalization...
The cellular host factors for severe fever with thrombocytopenia syndrome virus infection
June 2025
Severe fever with thrombocytopenia syndrome (SFTS) is a newly discovered life-threatening disease caused by SFTS virus (SFTSV), an emerging tick-borne bunyavirus. The severity of SFTSV infection can...
Rheumatoid arthritis animal model in mice
March 2025
Rheumatoid arthritis (RA) is an autoimmune disease that causes significant disability and has a high recurrence rate. Currently, there is no cure for this disease. Identifying the cause of RA and developing...
Advances in mammalian ovarian tissue cryopreservation
Available online 20 February 2025
In mammals, the ovum is one of the largest cells with a relatively small ratio of surface area to cytoplasm and unique biological characteristics. The quantity of ova in the ovary is very limited and...
Regulation of immune metabolism in Th17 and Treg cells
Available online 28 February 2025
Immunometabolism is the intersection between immunity and metabolism, and the effects of some important metabolic pathways on the development, differentiation, activation and function of immune cells...
Omega-3 polyunsaturated fatty acids, especially DHA and EPA, remold gut microbiota to suppress inflammation in rabbits with atherosclerosis
June 2025
Atherosclerosis (AS) caused by a high-fat diet becomes a critical cause of cardiovascular diseases, which has been regarded as an urgent public health problem. Omega-3 polyunsaturated fatty acids (omega-3...
Host immune response to Cryptosporidium spp.: Insights and perspectives for vaccine development
June 2025
Cryptosporidium, a zoonotic protozoan parasite, poses a significant threat to both public health and the livestock sectors globally, leading to lethal diarrheal disease and associated economic losses....
Critical role of cellular microRNAs in virus infection: Decades of progress
Available online 13 January 2025
MicroRNAs, or miRNAs, play a critical role in the complex interplay between viruses and their host organisms during viral infections. Over the past several decades, investigations into the functions...
Uncovering the profile of ubiquitination motif in catalytic proteins using sequence contextual features
June 2025
Ubiquitin molecules modify their target protein by conjugating the amino group of lysine side chain, thereby regulating the activity and function of most intracellular proteins. However, within multiple...
Prevention of Clostridium perfringens induced chicken necrotic enteritis by probiotics: A review
Available online 21 February 2025
Necrotic enteritis (NE), predominantly affecting poultry with significant disorder, is mainly caused by bacterial pathogen Clostridium perfringens. The restriction of growth enhancers based on animal...
Emerging role of ruminal microbiota in the development of perinatal bovine diseases
March 2025
As the largest and most important digestive organ of ruminant, rumen was a natural fermentation tank of dairy cows, in which there were many kinds of microorganisms. These microorganisms constituted...
Epidemiological survey of cat infectious diseases in China from 2022 to 2023
Available online 10 April 2025
The study investigates and analyzes the positive rates of 11 cat pathogens in 14 provinces across China from 2022 to 2023. The aim is to enhance understanding of the epidemiological characteristics...
CARS2 modulates cell malignant transformation induced by IFN-γ through manipulation of arginine metabolism in bovine mammary epithelial cells
Available online 21 July 2025
Malignant transformation induced by IFN-γ in bovine mammary epithelial cells (BMECs) is a pathological process that affects multiple cellular functions, including impaired milk fat synthesis. But the...
Current review for biological control of six common environmental mycotoxins
Available online 15 May 2025
Aflatoxin B1 (AFB1), zearalenone (ZEN), deoxynivalenol (DON), T-2 toxin (T-2), fumonisin B1 (FB1) and ochratoxin A (OTA) are the 6 most common environmental mycotoxins that are widely present in food...
Emerging challenges and advances in porcine viral pathogenesis: A decade in review
Available online 4 July 2025
The past decade has witnessed unprecedented challenges posed by porcine viruses, driven by globalization and intensive livestock practices. This review consolidates critical findings from recent literature,...
First report of a pure growth of Providencia stuartii infection in the United Kingdom isolated from a dog with suppurative otitis
Available online 13 May 2025
The authors report a seven-year-old dog imported from Romania with otitis caused by a pure growth of Providencia stuartii. This has rarely been isolated in the UK but never been described as the single...
CRISPR/Cas13a-based RNA analysis for non-enrichment Listeria monocytogenes in food
June 2025
Listeria monocytogenes (LM) is an opportunistic and invasive Gram-positive bacterium. They can grow in foods that are closely related to humans. However, the development of rapid and sensitive methods...
Promising strategies for accelerating the eradication of avian leukosis in China
Available online 18 March 2025
The national breeding and disease eradication programs in China are crucial for the healthy and sustainable development of the poultry industry. Among them, avian leukosis virus, the causative agent...
Thermal shift assay (TSA)-based drug screening strategy for rapid discovery of inhibitors against the Nsp13 helicase of SARS-CoV-2
March 2025
The pandemic of coronavirus disease 2019 (COVID-19) is no longer a global health emergency, but variants of the causative agent (severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2) are still...