Early Career Editorial Board Member Interview: Carlotta Pucci

Carlotta Pucci obtained a Ph.D. in Chemical Sciences at the University of Rome “La Sapienza” in 2014. During her Ph.D. she worked on the development of new synthetic catanionic vesicles and their interaction with biomacromolecules, in collaboration with the Institut de Quimica Avançada de Catalunya (Barcelona, Spain). In 2015, she was awarded the IdEX fellowship by the University of Bordeaux to study the out-of-equilibrium self-assembly of polymers and block copolymers at the Centre de Recherche Paul Pascal and at the Laboratoire de Chimie des Polymères Organiques in Bordeaux (France). In 2018, she moved to the Center for Materials Interfaces of the Italian Institute of Technology in Pontedera (Italy), where she worked on projects funded by different agencies (e.g., ERC, AIRC), focusing on the synthesis and characterization of stimuli-responsive nanoparticles for the treatment of tumor or oxidative stress-associated pathologies. In January 2024, she joined the “Regenerative Technologies” Lab to work on the synthesis and characterization of smart stimuli-responsive biomaterials for regenerative medicine.

Here is the interview we did with him:

1. Could you briefly introduce the specific focus of your current research within the broad area of bioactive materials?

My research primarily focuses on the development of stimuli-responsive nanomaterials as multifunctional bioactive platforms for targeted drug delivery, particularly in the context of aggressive brain tumors and tissue engineering. I’m especially interested in engineering nanoparticles that selectively respond to external stimuli, such as ultrasound and light, to deliver spatiotemporally controlled therapeutic functions. My main objective is to find bioactive materials that are also biocompatible and biodegradable.

2. In the context of researching bioactive materials, what unique obstacles or difficulties have you faced?

One of the key challenges has been achieving a balance between biological functionality and physicochemical stability. For instance, incorporating biologically active surface modifications onto nanocarriers can sometimes compromise formulation stability or reproducibility. Additionally, translating promising in vitro findings into meaningful in vivo outcomes remains a persistent and exciting hurdle.

3. How do you stay updated with the latest advancements in research, considering the rapidly evolving nature of the field?

I regularly follow high-impact journals in materials science and nanomedicine, attend international conferences, and engage in discussions within interdisciplinary research networks.

4. What were the key factors that attracted you to become an early career editorial board member of Bioactive Materials?

My interest in Bioactive Materials relies on its strong focus on cutting-edge interdisciplinary research fields that include materials science, biology, chemistry and bioengineering. Being part of the early career editorial board is an exciting opportunity and it gives me the opportunity to support a community I’m deeply passionate about.

5. From your perspective, what are the most promising directions for the future development of Bioactive Materials?

In my opinion, the future development of bioactive materials should integrate more aspects concerning precision medicine, such as patient-specific delivery platforms and stimuli-responsive systems. Additionally, advances in bioinspired materials should also be considered.

6. As an early career editorial board member, what initiatives do you plan to take to engage more early-career researchers with the journal and the field of bioactive materials?

I hope to help launch initiatives like themed issues led by early-career researchers, mentoring and workshops. Creating more inclusive spaces for early-career scientists to share their work and perspectives should be a priority.

7. Beyond your scientific endeavors in bioactive materials, what is your favorite pastime?

Outside the lab, I really enjoy spending time with my friends and family. When I need to recharge my batteries, I like walking by the sea or relaxing by reading a book.

8. Given the demanding nature of scientific research, how do you manage to strike a balance between your research work and your personal life?

I try to maintain clear boundaries between lab time and personal time. Sometimes, a little break is helpful not only for our own well-being, but also for boosting creativity.