Micro/nanorobots with remote sensing capabilities for intelligent and miniaturized biomedical platforms
December 2025
Micro/nanorobots equipped with remote biosensing capabilities represent a significant advancement in biomedical applications, offering innovative solutions for diagnostics and targeted therapies. These...
From PCR to CRISPR: Comparing the detection performance of different nucleic acid detection technologies
December 2025
Real-time quantitative PCR (qPCR) is the gold standard for viral nucleic acid detection but requires specialized laboratories, trained personnel, and costly equipment, resulting in prolonged testing...
Ultrafast Polymerase Chain Reaction on MEMS Microheater
Available online 9 December 2025
Ultrafast polymerase chain reaction (PCR) is crucial for the rapid detection of pathogens, particularly in medical emergencies and public health scenarios. Conventional PCR systems, however, require...
Portable fully integrated POCT device based on digital microfluidic technology
September 2025
With the increasing demand for rapid diagnostic devices, traditional biological detection systems face challenges such as prolonged reaction times, single-parameter detection, complex operation, and...
Microfluidic instruments for nanoparticle synthesis
September 2025
Nanomaterials have been widely applied in numerous cutting-edge research fields due to their unique size effects and distinctive physical, chemical, and biological properties. With the advancement of...
Label-free 8-part leukocyte differential enabled by imaging flow cytometry of acoustic focusing and deep neural network of ResNet-18
September 2025
Leukocyte differential analysis represents a critical first-line diagnostic tool in clinical examinations. However, conventional methodologies exhibit significant limitations: Automated slide stainers...
Facile nanostructures via nanoimprinting for biomedical devices
September 2025
With the rapid advancement of micro- and nanofabrication technologies, nanoimprint lithography (NIL) and nano-transfer printing (nTP) have become key methods for creating micro- and nanostructures,...
Wavelength-phase hybrid coding optical fiber intrarenal pressure and temperature sensor for flexible ureteroscopy laser lithotripsy
September 2025
This paper proposes a novel optical fiber composite sensor for intrarenal pressure and temperature monitoring during flexible ureteroscopy laser lithotripsy. The sensor is made of all-silicon material,...
Hydrogel-based smart contact lens for enhanced functional applications
September 2025
The human eye emerges as a vital sensory organ in the visual system, harboring a wealth of physiological data and playing a crucial role in overall well-being. The demand for smart contact lenses (SCLs)...
Isolation and detection of exosomes on microfluidic chips
September 2025
Exosomes are a type of cell-derived extracellular vesicles (EVs) between 30 and 150 nm in diameter, which carry abundant lipid, proteins, and genetic materials. Over the past few years, exosomes have...
BMI: Bridge the gap between biomedicine and engineering
September 2025