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ISSN: 2949-723X

Nanomaterials for wound healing: Current status and futuristic frontier

Wound healing is a complex process that involves a variety of physical, chemical, and biological processes. Because of their remarkable characteristics and capabilities, nanomaterials have recently...

Emerging strategies for the treatment of endometriosis

Endometriosis is an estrogen-dependent disorder of the reproductive tract, affecting approximately 10 ​% of women. The symptoms of this condition are vague and not correlated with the disease's stage....

Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment

This review evaluates the literature on nanoparticle-based drug delivery systems for cancer treatment and assesses their efficacy. Nanoparticles have shown potential for improving anticancer agent delivery,...

A review on selenium nanoparticles and their biomedical applications

Nanotechnology has enormous promise for a wide range of applications in biology. Nanoparticles (NPs) have the benefit of improving bioactivity, decreasing toxicity, allowing for precision targeting,...

Decellularized extracellular matrix: Advanced bioplatforms for functional tissue restoration via innovative decellularization techniques

In recent years, tissue engineering has experienced rapid development, with bioscaffolds emerging as a focal point of research due to their favorable bioactivity, biocompatibility, and capacity to provide...

Next-generation 3D bioprinted inner ear organoids

Inner ear is crucial for maintaining normal functions of human sensory perception. However, current perceptual reconstruction is mostly limited to symptomatic relief and lacks a radical cure for irreversible...

A multiscale biohybrid strategy using biostable and biodegradable polymers to develop a growth-accommodating heart valved conduit for children

Congenital heart diseases affect nearly 1% of births and often require valve replacement. Current prostheses lack growth potential and regenerative capacity, necessitating repeated surgeries. Tissue-engineered...

Exploring the revolution in healthcare systems through the applications of digital twin technology

Digital Twin is a virtual replica of an item that is gaining traction in several sectors. This technology is creating significant advancements in the field of healthcare. A machine or a person's digital...

Advanced AI-based technologies for early detection and personalized management of cervical cancer

Cervical cancer is one of the leading causes of cancer-related deaths among women worldwide, imposing a particularly heavy burden in low- and middle-income countries. In recent years, advanced artificial...

Bacterial extracellular vesicle technology for precision cancer medicine: Biotechnological advances and applications

Bacterial extracellular vesicles (BEVs) are nanoscale secretions containing proteins, lipids, nucleic acids, and metabolites that modulate immune pathways, reshape the tumor microenvironment, and influence...

Sustaining the healthcare systems through the conceptual of biomedical engineering: A study with recent and future potentials

Biomedical engineering is an interdisciplinary branch of engineering & technology that combines biomedical sciences with engineering principles. This discipline covers broad areas where biomedical engineers...

A comprehensive review on carbon quantum dots as an effective photosensitizer and drug delivery system for cancer treatment

Carbon quantum dots (CQDs) are an emerging class of carbon-based nanomaterials. CQDs are receiving considerable interest in biomedical applications due to their low toxicity, stability profile, efficient...

Antibacterial hydrogels for bacteria-infected wound treatment

Bacteria-infected wounds are enormous clinical obstacles and cause huge burdens to patients and society. Recently, many biomaterials are designed to treat bacterial infected wounds. Among various biomaterials,...

Integrated tardigrade-based biomimetic strategy and stem cell expansion and differentiation for a novel radioprotection approach

Tardigrades have attracted widespread research attention due to their extraordinary radiotolerance, of which the damage suppressor protein (DSUP) is regarded as a key molecule responsible for their...

Mechanically engineered extracellular vesicles technology: Regulatory mechanisms and therapeutic applications in orthopedic diseases

An increasing number of studies have shown that extracellular vesicles (EVs), as key mediators of intercellular communication, serve as a crucial bridge between the mechanical microenvironment and bone...

Intradermal delivery of N1-methylpseudouridine-modified BCL-2 mRNA as a programmable gene therapy to reverse UVB-induced skin photoaging

Photoaging, driven by ultraviolet-B (UVB)–induced oxidative and inflammatory cascades, accelerates extracellular-matrix degradation and remains difficult to reverse with current small-molecule, topical,...

Multi-omics advances in understanding cancer drug resistance

Cancer drug resistance presents a significant challenge in modern oncology, necessitating detailed exploration of its underlying mechanisms and the development of effective counterstrategies. This review...

One-step microfluidic technology for generating multifunctional quantum dot (QD) biomarker barcode particles for multiplex pathogen detection

High throughput, multiplex analysis, and operational convenience are essential for biomedical diagnostics. Quantum dot (QD) barcode particles hold significant promise for biomarker detection due to...

Wireless bioelectric stimulation for bone regeneration using magnetoelectric PVDF/BaTiO3 – Fe80Ga20 laminates

Fracture healing remains a significant clinical challenge, particularly in cases of delayed or impaired recovery, often hindered by inadequate vascularization, patient variability. Conventional stimulation...

Dynamic mechanical properties of the rat aged spinal cord tissue: Characterization of elasticity, viscoelasticity, and non-linearity

Ageing plays a pivotal role in spinal cord (SC)-related disorders, but the impact of ageing on the SC, especially with respect to its material properties, remains poorly understood. Prior investigations...

Advanced 3D biomaterials and bioprinting strategies for in vitro modeling of neurodegenerative diseases

Neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) remain a major global health challenge due...

Microenvironment-feedback hydrogel for precise sequential repair of acute infectious wounds

The healing of acute infected wounds is a multi-stage and sequential biological process. Traditional antibacterial dressings are usually a simple superposition of antibacterial properties and active...

Redox-responsive carrier-free nanoassemblies enable dual topoisomerase I/II inhibition for metastasis-suppressed breast cancer therapy

Breast cancer remains a critical unmet clinical challenge due to its aggressive metastasis behavior and limited treatment options. Topoisomerase inhibitors are widely available clinically but fail to...

Precision and customization in regenerative medicine: The role of coaxial 3D printing

Coaxial three-dimensional (3D) printing enables precise, multi-material deposition, demonstrating strong potential across diverse fields, including industrial monitoring, health sensing, artificial...

A high-throughput immunopeptidome platform for MHC II alleles to characterize antigen-specific CD4+ T cells

CD4+ T cells play a pivotal role in adaptive immunity, recognizing peptide antigens presented by MHC II molecules during infections and tumor development. Identifying immunodominant MHC II epitopess...

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