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ISSN: 2949-9240

Recurrent cholera outbreaks in Nigeria: A review of the underlying factors and redress

Cholera outbreaks remain a matter of public health since this outbreak of the epidemic is experienced almost every year. In June 2024, the African Region had registered 7964 new cases of cholera across...

WHO report signals tuberculosis resurgence: Addressing systemic failures and revamping control strategies

According to the World Health Organization's Global Tuberculosis Report 2024, tuberculosis (TB) has resurged as the leading cause of death from a single infectious agent, overtaking Coronavirus disease...

Emergencies of zoonotic diseases, drivers, and the role of artificial intelligence in tracking the epidemic and pandemics

Zoonotic illnesses are defined as diseases that can be transmitted from animals to humans through various channels. More than sixty percent of disease-causing organisms capable of affecting humans are...

Global, regional, and national burden of dengue, 1990–2021: Findings from the global burden of disease study 2021

Dengue is an acute viral infectious disease caused by the dengue virus and transmitted through mosquitoes. Although numerous studies have examined the global burden of dengue, comprehensive and systematic...

Rabies in Africa: Vaccination coverage and strategies for elimination by 2030

Rabies remains a significant public health threat in Africa, and disproportionately impacts vulnerable populations to cause thousands of deaths annually. Rabies is a preventable disease and control...

Influences of vaginal microbiota on human papillomavirus infection and host immune regulation: What we have learned?

The alteration of microbiota in different host niches has been associated with numerous adverse health outcomes that affect millions of human patients annually. In last few years the interest has been...

Global, regional, and national burden of malaria, 1990–2021: Findings from the global burden of disease study 2021

Malaria is an infectious disease transmitted by mosquitoes and caused by Plasmodium parasites. This study analyzes data from the Global Burden of Disease (GBD) Study 2021 to systematically assess global...

Machine learning models for predicting residual malaria infections using environmental factors: A case study of the Jazan region, Kingdom of Saudi Arabia

Malaria is a global public health problem affecting more than 100 countries. Meteorological factors on the other hand represent a major driving force behind malaria transmission and other vector-borne...

A review of epidemiological characteristics, risk factors, and prevention strategies of human anthrax in China

Anthrax is a severe infectious illness triggered by the bacterium Bacillus anthracis. This bacterium is naturally found in soil and mainly impacts domestic and wild animals. Human anthrax infection...

Maternal immune activation and neuropsychiatric disease in offspring: Pathogen's perspective

Neuropsychiatric disorders (NDDs) have been associated with maternal immune activation (MIA) in epidemiologic studies, such as prospective birth cohort studies. There is evidence linking maternal infectious...

mRNA vaccination facilitates the prevention and control of infectious diseases at an unprecedented speed

In recent years, amidst the progresses of biotechnology versus the emergence and evolution of diseases, the pursuit of mRNA (messenger RNA) vaccines has become a focal point, particularly after their...

Circadian rhythm of mosquitoes: Blood feeding and disease transmission

The circadian rhythm refers to the adjustment of behavioural rhythms of organisms' to the environmental cues. The rhythm adjusting and maintaining is done through an internal timekeeping mechanism....

The prevalence, diagnosis, and dissemination of mcr-1 in colistin resistance: Progress and challenge

Considered as the last defense line against Gram-negative bacteria, colistin is particularly effective against multiple drug-resistant bacteria such as multi-drug resistance (MDR) and carbapenem-resistant...

A novel approach to disease modeling: The SEIVR model with a vulnerable compartment

The SEIR model is a cornerstone in epidemiology and offers insights into the spread of infectious diseases. It extends the basic SIR model to include an Exposed (E) compartment, to account for the incubation...

Efforts of rabies elimination with a One Health approach and SARE tools in Ethiopia

Rabies is a viral zoonosis which affects nearly every region of the world. Once symptoms appear, the disease is 100 % fatal, although it is 100 % preventable through vaccination. Human rabies is typically...

The Alongshan virus: A comprehensive review of its pathogenic characteristics, epidemiology, and detection strategies

Alongshan virus (ALSV) is an emerging tick-borne segmented RNA virus belonging to the Flaviviridae family, first identified in Northeastern China in 2017. ALSV is currently classified within the Jingmenvirus...

Recent malaria outbreak in the USA: Risk of and response to malaria reintroduction in non-endemic regions

The emergence of locally transmitted Plasmodium vivax malaria in Florida from May to July 2023 underscores the persistent threat of malaria reintroduction in non-endemic regions. The increasing instances...

Advances and challenges in the prevention, control and research of echinococcosis in China

Echinococcosis is a group of chronic zoonotic parasitic diseases caused by the larval stage of Echinococcus tapeworms, which infect both humans and animals. Due to the complex life cycle, broad geographic...

The impact of environmental and host factors on wolbachia density and efficacy as a biological tool

Wolbachia, a bacterium found naturally in some species of Aedes and Culex mosquitoes, has gained significant attention for it's potential in controlling mosquito-borne diseases and suppressing mosquito...

Genotype switching in hepatitis B virus as a potential risk for vertical transmission from mother-to-child was first reported

Hepatitis B virus (HBV) infection represents a significant global public health concern and is endemic in numerous populations. In China, mother-to-child transmission (MTCT) remains the predominant...

Trends in the minimum inhibitory concentrations for four agents against methicillin-resistant Staphylococcus aureus in bloodstream infections in China: a 6-year multi-center study from 2017 to 2022

Staphylococcus aureus bacteremia is a critical and pernicious infection, and in particular methicillin-resistant Staphylococcus aureus (MRSA) is increasing in treatment failure. This study analyzed...

S–6P exhibits better immunogenicity than S–2P at lower doses of COVID-19 mRNA vaccines

The objective of this study was to determine whether a new combination of immunogens could be more effective than the S–2P design in terms of eliciting an immune response. The study aimed to use a unified...

Chromosome-level genome assembly, reannotation and decoding of a Trichomonas vaginalis clinical isolate from Shiyan, Central China

Trichomonas vaginalis trophozoite is a pathogen that causes trichomoniasis, the most common neglected sexually transmitted disease. The reference genome of T. vaginalis is derived from the G3 strain....

Decoding the Bite: Sensory cues, host heterogeneity, and pathogen manipulation in mosquito host-seeking behavior

Mosquitoes, primarily females, require blood meals for reproduction, making them prolific biters and major vectors of diseases such as malaria, dengue, Zika, and West Nile. This review synthesizes the...

Progress of exosomes in diagnosis of tuberculosis

Tuberculosis (TB) is a globally prevalent infectious disease caused by Mycobacterium tuberculosis. A majority of TB patients develop a latent infection, making disease diagnosis more challenging. However,...

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