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Open access

ISSN: 2150-5578
CN: CN 31-2196/Q
p-ISSN: 2097-3837

Nanozymes in immune regulation: Applications and progress

The immune system is essential for maintaining physiological balance, defending against pathogens, and eliminating abnormal cells. Immune dysregulation—manifesting as either suppression or hyperactivation—plays...

Recent progress in nanomaterials for the detection of rheumatoid arthritis-related biomarkers: A clinical perspective

Rheumatoid arthritis (RA) is a chronic and highly disabling autoimmune disorder. Highly sensitive detection and accurate quantification of biomarkers associated with RA are crucial for early diagnosis...

Research application of immunomodulatory nanomaterials in Alzheimer's disease vaccine development

Alzheimer's disease (AD) is a common neurodegenerative disorder, and there is currently no effective treatment, which brings a significant burden to patients and their families. In recent years, immunomodulatory...

Special issue: Nanomaterials for immunomodulation

Engineered exosome based immunomodulation therapies: Advancements and clinical applications

Exosome applications in biomedicine have gained momentum in the last two decades, mainly due to their remarkable versatility. Exosomes are extracellular vesicles that carry diverse nucleic acids, proteins,...

Therapeutic applications of immunomodulatory nanomaterials in bladder cancer

Bladder cancer (BC) exhibits limited responsiveness to conventional therapies such as intravesical immunotherapy and chemotherapy, alongside high recurrence rates and significant treatment costs. Recent...

Atomically engineered nanozymes (AEN): Revolutionizing catalytic immunemodulation for biomedical advances

Immunotherapy holds enormous potential to improve treatment results, however, the low response rate remains a significant challenge. Conventional immunomodulatory methods often cause off-target effects,...

Lactate oxidase-integrated nanomaterials for tumor microenvironment modulation: Mechanisms and therapeutic applications

The tumor microenvironment (TME) is dynamically remodeled by metabolic reprogramming, establishing lactate as a central orchestrator of immune evasion through acidosis, CD8⁺ T cell suppression, and...

Design of nanomaterials for enhanced cancer immunotherapy: A review

Nanomaterials for precise tumor targeting have entered the era of intelligent medicine, where their versatile applications are being widely studied. In the field of tumor treatment, nanomaterial-based...

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