Nanozymes in immune regulation: Applications and progress
March 2026
The immune system is essential for maintaining physiological balance, defending against pathogens, and eliminating abnormal cells. Immune dysregulation—manifesting as either suppression or hyperactivation—plays...
Research application of immunomodulatory nanomaterials in Alzheimer's disease vaccine development
March 2026
Alzheimer's disease (AD) is a common neurodegenerative disorder, and there is currently no effective treatment, which brings a significant burden to patients and their families. In recent years, immunomodulatory...
Engineered exosome based immunomodulation therapies: Advancements and clinical applications
March 2026
Exosome applications in biomedicine have gained momentum in the last two decades, mainly due to their remarkable versatility. Exosomes are extracellular vesicles that carry diverse nucleic acids, proteins,...
Lactate oxidase-integrated nanomaterials for tumor microenvironment modulation: Mechanisms and therapeutic applications
March 2026
The tumor microenvironment (TME) is dynamically remodeled by metabolic reprogramming, establishing lactate as a central orchestrator of immune evasion through acidosis, CD8⁺ T cell suppression, and...
Design of nanomaterials for enhanced cancer immunotherapy: A review
March 2026
Nanomaterials for precise tumor targeting have entered the era of intelligent medicine, where their versatile applications are being widely studied. In the field of tumor treatment, nanomaterial-based...
Atomically engineered nanozymes (AEN): Revolutionizing catalytic immunemodulation for biomedical advances
March 2026
Immunotherapy holds enormous potential to improve treatment results, however, the low response rate remains a significant challenge. Conventional immunomodulatory methods often cause off-target effects,...
Therapeutic applications of immunomodulatory nanomaterials in bladder cancer
March 2026
Bladder cancer (BC) exhibits limited responsiveness to conventional therapies such as intravesical immunotherapy and chemotherapy, alongside high recurrence rates and significant treatment costs. Recent...
Recent progress in nanomaterials for the detection of rheumatoid arthritis-related biomarkers: A clinical perspective
March 2026
Rheumatoid arthritis (RA) is a chronic and highly disabling autoimmune disorder. Highly sensitive detection and accurate quantification of biomarkers associated with RA are crucial for early diagnosis...
Oral nanomaterial formulations for gastrointestinal therapeutics: Promises and challenges on the path to clinical translation
June 2026
The gastrointestinal (GI) tract is an important route of drug delivery in the human body, offering advantages such as ease of administration, high patient compliance, and systemic delivery or targeted...
Optimizing design and exploring the dual potential of carbon quantum dots in environmental sensing and biomedical theranostics
June 2026
Carbon quantum dots (CQDs) have emerged as next-generation nanomaterials owing to their tunable photoluminescence, chemical stability, biocompatibility, and facile synthesis from renewable precursors....
Ratiometric SERS platform of dual bioprobes for stable detection of circulating tumor cells
June 2026
Circulating tumor cells (CTCs) serve as crucial biomarkers for non-invasive cancer diagnostics through liquid biopsy. Surface-enhanced Raman spectroscopy (SERS) bioprobes offer high detection sensitivity...