Advancing antimicrobial peptides: Mechanisms, design, and applications in the post-antibiotic era
August 2026
The rapid emergence of multidrug-resistant and extensively drug-resistant bacteria has intensified the need for alternative antimicrobial strategies in the post-antibiotic era. Antimicrobial peptides...
CD44v6- and VEGFR2-targeting antibody-drug conjugates: Enhancing precision and safety in cancer therapy through a dual-targeting strategy
August 2026
Bispecific antibody-drug conjugates (BsADCs) represent a promising therapeutic strategy to overcome single-target resistance. Here, we developed a dual-targeting BsADC that simultaneously recognizes...
Efficiency and specificity evaluation of imidazole derivatization reactions for histidine-containing peptides
August 2026
Histidine residues are crucial for protein structure and function, playing key roles in metal coordination, catalysis, and post translational modifications. Comprehensive profiling of functional histidine...
Heat Shock Proteins as Modulators of Cardiovascular Health and Disease: From Cellular Stress to Clinical Targets
Available online 19 August 2026
Cardiovascular disease (CVD) is a result of complex pathophysiological processes affecting the heart and blood vessels. Heat shock proteins (HSPs) are evolutionarily conserved molecular chaperones that...