A new cell factory for high-efficiency production of ectoine
Published 08 November, 2021
A study published in the KeAi journal Green Chemical Engineering, has reported the biotechnological construction of an efficient ectoine cell factory based on E. coli BL21(DE3). Using metabolic engineering, researchers synthesised the ectoine with the E. coli, using glucose as the sole carbon source. By reconstructing the ectoine synthetic pathway, and enhancing the biosynthesis of ectoine precursor in E. coli, a high level of 60.7 g/L of ectoine was produced using a fed-batch fermentation approach.