Most Downloaded Articles

ISSN: 2589-3777

CN: 43-1540/R

p-ISSN: 2096-479X

Recommended Medicinal Plants as Source of Natural Products: A Review

June 2018

Natural product is one of the sources of drugs in pharmaceutical industry, and one of the notable origin of natural product is the medicinal plants. Medicinal plants tend to cure some certain diseases...

Medicinal properties and anti-inflammatory components of Phytolacca (Shanglu)

October 2021

Christian Bailly

(Shanglu) is a well-known traditional herbal medicine that has been used for thousands of years in China. Phytolacca is also used worldwide in different traditional phyto-medicines and homeopathic preparations....

Herbal remedies for Alzheimer’s disease: neuroprotective mechanisms and cognitive enhancement potential

June 2025

Dharmalingam Kirubakaran

Alzheimer’s disease (AD) is a progressive neurodegenerative condition characterized by memory loss and cognitive decline. Current drugs offer limited benefits and often cause side effects. Recently,...

Correlation Between Helicobacter pylori Infection and Tongue Manifestations: A Meta-analysis

June 2018

Objective To analyze the relationship between Helicobacter pylori (H. pylori) infection and the manifestations of the tongue....

Research status and prospect of tongue image diagnosis analysis based on machine learning

March 2024

X.U. Jiatuo | J.I.A.N.G. Tao | L.I.U. Shi

Image-based intelligent diagnosis represents a trending research direction in the field of tongue diagnosis in traditional Chinese medicine (TCM). In recent years, machine learning techniques, including...

Quantum theory-based physical model of the human body in TCM

December 2022

Shuna SONG | Zhensu SHE

In the study, a quantum resonant cavity model based on wave-particle duality was proposed for the explanation of the dynamic processes of essence, vigor, and spirit in the human body in traditional...

TCMLLM-PR: evaluation of large language models for prescription recommendation in traditional Chinese medicine

December 2024

To develop and evaluate a fine-tuned large language model (LLM) for traditional Chinese medicine (TCM) prescription recommendation named TCMLLM-PR....

From digits towards digitization: the past, present, and future of traditional Chinese medicine

March 2025

Qi Wang

Digitization is the inevitable path for the natural development of traditional Chinese medicine (TCM) in the context of the Fourth Industrial Revolution. The goal of TCM digitization is to generate...

Artificial intelligence meets traditional Chinese medicine: a bridge to opening the magic box of sphygmopalpation for pulse pattern recognition

March 2021

Artificial intelligence (AI) aims to mimic human cognitive functions and execute intellectual activities like that performed by humans dealing with an uncertain environment. The rapid development...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377722000799" target="_blank" rel="noreferrer" > A new interpretation of TCM pulse diagnosis based on quantum physical model of the human body </a> </h2> <p class="article-date">December 2022</p> <p class="article-authors"> Shuna SONG | Zhensu SHE</p> <p class="article-abstract">Following the quantum theory-based physical model of the human body, a new interpretation of the traditional Chinese medicine (TCM) principle of “Cunkou reads viscera” is presented. Then, a Gaussian...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377725000989" target="_blank" rel="noreferrer" > Advances and prospects of the integration of multi-omics and artificial intelligence in traditional Chinese medicine research </a> </h2> <p class="article-date">September 2025</p> <p class="article-authors"> L.I.U. Guicheng | L.O.N.G. Xi | P.E.N.G. Qinghua | T.I.A.N. Sainan | H.U. Shujuan</p> <p class="article-abstract">To map the research hotspots, developmental trends, and existing challenges in the integration of artificial intelligence (AI) with multi-omics in traditional Chinese medicine (TCM) through comprehensive...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377725000035" target="_blank" rel="noreferrer" > Harnessing traditional herbal medicine: molecular insights into diabetic wound healing for modern therapeutics </a> </h2> <p class="article-date">December 2024</p> <p class="article-authors"> Pavithra Bharathy | Punniyakoti Veeraveedu Thanikachalam</p> <p class="article-abstract">This study aims to explore the molecular aspects of the wound-healing potential of medicinal plants through preclinical and clinical research. This review focuses on the theoretical support and therapeutic...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377720300501" target="_blank" rel="noreferrer" > Mathematical Analysis of the Meridian System in Traditional Chinese Medicine </a> </h2> <p class="article-date">September 2020</p> <p class="article-authors"> Wan Xiao-Hai</p> <p class="article-abstract">Energy expenditure of the meridian system in traditional Chinese medicine (TCM) for living human bodies is one of the fundamental questions regarding the physical properties of the meridian system....</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377725000746" target="_blank" rel="noreferrer" > Clinical research report on Chinese patent medicines and classic traditional Chinese medicine prescriptions (2023) </a> </h2> <p class="article-date">June 2025</p> <p class="article-authors"> Xiaolei Wu | Haiyin Hu | Yuetong Wang | Alice Josephine Fauci | Yazi Zhang | Wenting Song | Fengwen Yang | Boli Zhang | Junhua Zhang | Zhaochen Ji</p> <p class="article-abstract">Randomized controlled trials (RCTs) of Chinese patent medicines and classic traditional Chinese medicine prescriptions were systematically reviewed from both Chinese and English journals published in...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S258937772200074X" target="_blank" rel="noreferrer" > Data-driven based four examinations in TCM: a survey </a> </h2> <p class="article-date">December 2022</p> <p class="article-authors"> Dong SUI | Lei ZHANG | Fei YANG</p> <p class="article-abstract">Traditional Chinese medicine (TCM) diagnosis is a unique disease diagnosis method with thousands of years of TCM theory and effective experience. Its thinking mode in the process is different from that...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S258937772100046X" target="_blank" rel="noreferrer" > Systematic review of robust experimental models of rheumatoid arthritis for basic research </a> </h2> <p class="article-date">December 2021</p> <p class="article-authors"> Lin Ye | Hu Mingyue | Zhang Feng | Dai Zongshun | Xie Ying | Cai Xiong | Liu Liang</p> <p class="article-abstract">Rheumatoid arthritis (RA) is a common autoimmune disease characterized by progressive joint inflammation and destruction, deformity, loss of mobility, and permanent disability. Although the cellular...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377722000490" target="_blank" rel="noreferrer" > Tongue image segmentation and tongue color classification based on deep learning </a> </h2> <p class="article-date">September 2022</p> <p class="article-authors"> L.I.U. Wei | C.H.E.N. Jinming | L.I.U. Bo | H.U. Wei | W.U. Xingjin | Z.H.O.U. Hui</p> <p class="article-abstract">To propose two novel methods based on deep learning for computer-aided tongue diagnosis, including tongue image segmentation and tongue color classification, improving their diagnostic accuracy....</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377724000090" target="_blank" rel="noreferrer" > Efficacy and safety of Jiuhua hemorrhoid suppository plus diosmin for the treatment of hemorrhoid hemorrhage: a multicenter, randomized, and controlled trial </a> </h2> <p class="article-date">December 2023</p> <p class="article-authors"> Rong Xinqi | Wu Mingsheng | Xin Xuezhi | Zhang Bo | Liu Dianwen | Xiao Huirong | Wang Zhenyi | Cui Junhui | Wang Jianping | Wang Zhongcheng | Fan Xiaohua | Hu Ying | Rong Yisheng | Li Ying</p> <p class="article-abstract">To compare the efficacy and safety of combining diosmin with Jiuhua hemorrhoid suppository versus diosmin alone for the treatment of hemorrhoid hemorrhage....</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377724000582" target="_blank" rel="noreferrer" > Effects of needling at Sanyinjiao (SP6) acupuncture point on blood glucose levels and cardiovascular functions in patients with type 2 diabetes mellitus: a randomized placebo-controlled study </a> </h2> <p class="article-date">September 2024</p> <p class="article-authors"> S. Priyadharshini | A. Mooventhan | Venkatalakshmi Saravanan | N. Mangaiarkarasi</p> <p class="article-abstract">To determine the effect of needling at Sanyinjiao (SP6) on random blood glucose (RBG) levels and cardiovascular function in patients with type 2 diabetes mellitus (T2DM)....</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377725000217" target="_blank" rel="noreferrer" > Artificial intelligence in personalized cardiology treatment </a> </h2> <p class="article-date">March 2025</p> <p class="article-authors"> Abbas Mohammadi | Sheida Shokohyar</p> <p class="article-abstract">Cardiovascular diseases are the leading cause of death, requiring innovative approaches for prevention, diagnosis, and treatment. Personalized medicine customizes interventions according to individual...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377724000429" target="_blank" rel="noreferrer" > Deep learning-based recognition of stained tongue coating images </a> </h2> <p class="article-date">June 2024</p> <p class="article-authors"> Liqin Zhong | Guojiang Xin | Qinghua Peng | Ji Cui | Lei Zhu | Hao Liang</p> <p class="article-abstract">To build a dataset encompassing a large number of stained tongue coating images and process it using deep learning to automatically recognize stained tongue coating images....</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377724000405" target="_blank" rel="noreferrer" > Constitution identification model in traditional Chinese medicine based on multiple features </a> </h2> <p class="article-date">June 2024</p> <p class="article-authors"> Anying Xu | Tianshu Wang | Tao Yang | Han Xiao | Xiaoyu Zhang | Ziyan Wang | Qi Zhang | Xiao Li | Hongcai Shang | Kongfa Hu</p> <p class="article-abstract">To construct a precise model for identifying traditional Chinese medicine (TCM) constitutions, thereby offering optimized guidance for clinical diagnosis and treatment planning, and ultimately enhancing...</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377724000594" target="_blank" rel="noreferrer" > The gas discharge visualization (GDV) order parameter model based on the principle of mastering both permanence and change </a> </h2> <p class="article-date">September 2024</p> <p class="article-authors"> Yu Xin | Lei Zhang | Qiancheng Zhao | Yurong She | Zhensu She | Shuna Song</p> <p class="article-abstract">To investigate the human body’s complex system, and classify and characterize the human body’s health states with “a comprehensive integrated method from qualitative to quantitative”....</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377721000513" target="_blank" rel="noreferrer" > Protective effects of Fufang Ejiao Jiang against aplastic anemia assessed by network pharmacology and metabolomics strategy </a> </h2> <p class="article-date">December 2021</p> <p class="article-authors"> He Dan | Zhang Haichao | Yi Ziyang | Zhao Di | Zhang Shuihan</p> <p class="article-abstract">To elucidate the mechanisms underlying the therapeutic effects of Fufang Ejiao Jiang (复方阿胶浆, FFEJJ) on aplastic anemia (AA) using integrated network pharmacology and serum metabolomics....</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> <div class="panel"> <div class="article-listing" > <h2 class="h5 article-title"> <a href="http://www.sciencedirect.com/science/article/pii/S2589377723000137" target="_blank" rel="noreferrer" > Antidepressant-like active ingredients and their related mechanisms of functional foods or medicine and food homologous products </a> </h2> <p class="article-date">March 2023</p> <p class="article-authors"> Y.E. Tian | X.U. Mengtao | F.A.N.G. Jingpeng | W.U. Qinxuan | Z.O.U. Xiaoyan | Y.A.N. Fangqin | Q.I.N.G. Zhixing</p> <p class="article-abstract">To provide a new idea for the treatment of depression by summarizing the antidepressant effect and mechanism of active ingredients in functional food, and medicine and food homologous products....</p> </div> <div class="d-sm-flex align-items-sm-center justify-content-sm-between justify-content-md-start"> </div> </div> </section> </div> <div class="col-12 col-xl-3"> <div class="d-grid gap-3 mb-3 journalCTAs"> <a href="https://www.editorialmanager.com/dcmed/Default.aspx" class="btn btn-primary btn-lg" target="_blank" rel="noreferrer"> Submit your paper </a> <a href="https://www.sciencedirect.com/journal/digital-chinese-medicine" class="btn btn-outline-primary btn-lg" target="_blank" rel="noreferrer"> View articles </a> </div> <ul class="list-group list-group-flush"> <li class="list-group-item"> <a class="action-link text-wrap" href="/en/journals/digital-chinese-medicine/guide-for-authors/" > <i class="bi bi-chevron-right"></i>Guide for Authors </a> </li> <li class="list-group-item"> <a class="action-link text-wrap" href="/en/journals/digital-chinese-medicine/abstracting-and-indexing/" > <i class="bi bi-chevron-right"></i>Abstracting and Indexing </a> </li> </ul> <div class="d-grid gap-3 mb-3"> <a class="btn btn-outline-primary btn-lg text-wrap" href="/en/journals/digital-chinese-medicine/recent-articles/" > Recent Articles </a> <a class="btn btn-outline-primary btn-lg text-wrap" href="/en/journals/digital-chinese-medicine/most-downloaded-articles/" > Most Downloaded Articles </a> <a class="btn btn-outline-primary btn-lg text-wrap" href="/en/journals/digital-chinese-medicine/most-cited-articles/" > Most Cited Articles </a> <a class="btn btn-outline-primary btn-lg text-wrap" href="/en/journals/digital-chinese-medicine/news/" > News </a> </div> <div class="panelled-container"> <div class="panel"> <div id="umbraco_form_def4c6c89a9e44038daddb19fca065ba" class="umbraco-forms-form stayinformed umbraco-forms-floating"> <form action="/en/journals/digital-chinese-medicine/most-downloaded-articles/" enctype="multipart/form-data" id="formc4c0f31a2a3e42d4ba4810051090f5d2" method="post"><input data-val="true" data-val-required="The FormId field is required." name="FormId" type="hidden" value="def4c6c8-9a9e-4403-8dad-db19fca065ba" /><input data-val="true" data-val-required="The FormName field is required." name="FormName" type="hidden" value="#Stay informed" /><input data-val="true" data-val-required="The RecordId field is required." name="RecordId" type="hidden" value="00000000-0000-0000-0000-000000000000" /><input name="PreviousClicked" type="hidden" value="" /><input name="Theme" type="hidden" value="floating" /><input name="RedirectToPageId" type="hidden" value="" /> <input type="hidden" name="FormStep" value="0" /> <input type="hidden" name="RecordState" value="Q2ZESjhPVEJfRlV0YVR4S2hiRW5ZdGlEczdYRmRDZ1g1VUJxRDNiU1dQdzNUZEdON0Z6MmVXN1cwNVB6S205T0ZLYm93TTJmbVIzNVNsSm5kb0FicjQ4TUFMbms0MTZyUVo4U3BoUzlEbW9USmloUXBfOWJ3SjZLdlRLSkZldmJPZ2Z5S0E=" /> <div id="7c4e12e0-e26b-4af2-a312-6649ca7b5e4c"> <fieldset id="d83df139-0d23-4e0d-a2f3-df7411256907"> <div class=" umbraco-forms-field intro titleanddescription" > <div id="9323e01d-3126-4ab8-bbe1-6237a21abfda" data-umb="9323e01d-3126-4ab8-bbe1-6237a21abfda"> <h2>Stay Informed</h2> <p>Register your interest and receive email alerts tailored to your needs. 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