Artificial intelligence and its application for cardiovascular diseases in Chinese medicine
December 2022
Cardiovascular diseases (CVDs) are major disease burdens with high mortality worldwide. Early prediction of cardiovascular events can reduce the incidence of acute myocardial infarction and decrease...
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Construction and application of knowledge graph of Treatise on Febrile Diseases
December 2022
To establish the knowledge graph of “disease-syndrome-symptom-method-formula” in Treatise on Febrile Diseases (Shang Han Lun,《伤寒论》) for reducing the fuzziness and uncertainty of data, and for laying...
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A new interpretation of TCM pulse diagnosis based on quantum physical model of the human body
December 2022
Following the quantum theory-based physical model of the human body, a new interpretation of the traditional Chinese medicine (TCM) principle of “Cunkou reads viscera” is presented. Then, a Gaussian...
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Quantum theory-based physical model of the human body in TCM
December 2022
In the study, a quantum resonant cavity model based on wave-particle duality was proposed for the explanation of the dynamic processes of essence, vigor, and spirit in the human body in traditional...
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Heterogeneous graph construction and node representation learning method of Treatise on Febrile Diseases based on graph convolutional network
December 2022
To construct symptom-formula-herb heterogeneous graphs structured Treatise on Febrile Diseases (Shang Han Lun,《伤寒论》) dataset and explore an optimal learning method represented with node attributes based...
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Data-driven based four examinations in TCM: a survey
December 2022
Traditional Chinese medicine (TCM) diagnosis is a unique disease diagnosis method with thousands of years of TCM theory and effective experience. Its thinking mode in the process is different from that...
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Research on knowledge reasoning of TCM based on knowledge graphs
December 2022
With the widespread use of Internet, the amount of data in the field of traditional Chinese medicine (TCM) is growing exponentially. Consequently, there is much attention on the collection of useful...
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MF2ResU-Net: a multi-feature fusion deep learning architecture for retinal blood vessel segmentation
December 2022
For computer-aided Chinese medical diagnosis and aiming at the problem of insufficient segmentation, a novel multi-level method based on the multi-scale fusion residual neural network (MF2ResU-Net)...
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Application regularity of medicinal and dietary substances for patients during COVID-19 rehabilitation
September 2022
This study focused on the application regularity of medicinal and dietary substances (MDS) of traditional Chinese medicine (TCM) diet therapy during rehabilitation, in order to help patients with Corona...
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Exploring the phytoconstituents targeting TNF-α as potential lead compounds to treat inflammatory diseases: an in-silico approach
September 2022
To explore the anti-inflammatory phytoconstituents from various plant sources as tumour necrosis factor-α (TNF-α)-inhibitor, a mediator involved in the inflammatory disorder, by in silico molecular...
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Compound Chaijin Jieyu Tablets ameliorating insomnia complicated with depression by improving synaptic plasticity via regulating orexin A, melatonin, and acetylcholine contents
September 2022
To investigate the efficacy and mechanism of action of Compound Chaijin Jieyu Tablets (复方柴金解郁片, CCJJYT) in rats with insomnia complicated with depression....
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Application of Nuc-mtDNA and DNA methylation analysis in life science and medical studies
September 2022
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Tongue image segmentation and tongue color classification based on deep learning
September 2022
To propose two novel methods based on deep learning for computer-aided tongue diagnosis, including tongue image segmentation and tongue color classification, improving their diagnostic accuracy....
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Effects of Qingguang’an Granules on mitochondrial autophagy of retinal ganglion cells in rats with chronic ocular hypertension
September 2022
To investigate the effect and underlying mechanism of Qingguang’an Granules (青光安颗粒剂, QGAG) on mitochondrial autophagy (mitophagy) of retinal ganglion cells (RGCs) in rats with chronic ocular hypertension...
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Visual analysis of research hotspots and trends in the treatment of immune thrombocytopenia with traditional Chinese medicine
September 2022
Through bibliometrics and visual analysis of the related studies on traditional Chinese medicine (TCM) treatment of immune thrombocytopenia (ITP), this study aims to sort out the overall research progress,...
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Molecular modeling of alkaloids bouchardatine and orirenierine binding to sirtuin-1 (SIRT1)
September 2022
Bouchardatine (1) is a β-indoloquinazoline alkaloid isolated from the plant Bouchardatia neurococca, acting as a modulator of adipogenesis and lipogenesis, and as an anticancer agent. The natural product...
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Dietary silymarin ameliorating reproductive and lactation performance of sows via regulating body antioxidant and metabolism
September 2022
The experiment was conducted to explore the effects of silymarin on reproductive and lactation performance, serum antioxidants, and body metabolism of sows....
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Meta-analysis of the efficacy and safety of Huanglian Wendan Decoction alone or combined with western medicine in treating insomnia caused by phlegm-heat internal disturbance
September 2022
To evaluate the efficacy and safety of Huanglian Wendan Decoction (黄连温胆汤, HLWDD) alone or combined with western medicine in treating insomnia caused by phlegm-heat internal disturbance in recent 10...
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Living fossils unearthed by blasting human chromosomes with Neanderthal mtDNA
September 2022
The successful retrieval of ancient mitochondrial DNA (mtDNA) from Neanderthals provides powerful experimental evidence that clarifies the arguments between the out-of-Africa and multiregional models...
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Chaihu Longgu Muli Decoction relieving temporal lobe epilepsy in rats by inhibiting TLR4 signaling pathway through miR-146a-3p and miR-146a-5p
September 2022
To explore the effect and mechanism of Chaihu Longgu Muli Decoction (柴胡龙骨牡蛎汤, CHLGMLD) in rats with temporal lobe epilepsy (TLE)....
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Intra-set correlation analysis of medical records of thyroid cancer treated by traditional Chinese medicine Master ZHOU Zhongying
June 2022
Based on intra-set correlation analysis, this paper deconstructs the clinical medical records of traditional Chinese medicine (TCM) Master ZHOU Zhongying in treating thyroid cancer, and analyzes the...
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Traditional Chinese medicine Master XIONG Jibo’s medication experience in treating arthralgia syndrome through data mining
June 2022
This study aimed to examine and propagate the medication experience and group formula of traditional Chinese medicine (TCM) Master XIONG Jibo in diagnosing and treating arthralgia syndrome (AS) through...
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Extraction process in Chuantieling (CTL) based on the quality by design (QbD) concept
June 2022
This study aimed to design and optimize the water extraction process for Chuantieling (喘贴灵, CTL) based on the concept of quality by design (QbD)....
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Protective effects of Zuogui Jiangtang Jieyu Formula on hippocampal neurons in rats of diabetes complicated with depression via the TRP/KYN metabolic pathway
June 2022
To explore the protective effects and mechanism of Zuogui Jiangtang Jieyu Formula (左归降糖解郁方, ZGJTJYF) on hippocampal neurons in rats of diabetes complicated with depression (DD) via the TRP/KYN metabolic...
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