Attenuation of oxidative injury in retinal photoreceptor cells by Gouqizi (Lycii Fructus) and Danshen (Salviae Miltiorrhizae Radix et Rhizoma) through modulation of ANGPTL4
June 2026
To investigate the protective effects of Gouqizi (Lycii Fructus, GQZ)-Danshen (Salviae Miltiorrhizae Radix et Rhizoma, DS) against hydrogen peroxide (H2O2)-induced oxidative injury in 661W retinal photoreceptor...
Clinical efficacy and pharmacological basis of Mongolian medicine Manggari hot compress therapy for cervical spondylotic radiculopathy: a randomized controlled trial and serum pharmacochemistry study
June 2026
To systematically evaluate the clinical efficacy of topical preparations of Mongolian medicine Manggari hot compress therapy (hereafter referred to as Manggari hot compress therapy) in treating cervical...
HerbGL: a network propagation and graph regularization-based framework for herb pairs prediction in traditional Chinese medicine
June 2026
To address the challenges of systematically identifying herb pairs in traditional Chinese medicine (TCM), we proposed HerbGL, a framework for predicting potential herb pairs that integrates network...
Construction of the clinical diagnosis and treatment model during the “pre-disease to disease” window period in traditional Chinese medicine: integration of objective multimodal data from the perspective of traditional Chinese medicine stateology
June 2026
The philosophy of “treating disease before its onset” is a fundamental concept of traditional Chinese medicine (TCM), permeating its diagnostic and therapeutic framework, and is central to clinical...
Visualization analysis and clinical interpretability evaluation of artificial intelligence-assisted tongue diagnosis
June 2026
To map the research landscape of artificial intelligence (AI)-assisted tongue diagnosis through bibliometric analysis and to quantify its diagnostic accuracy and clinical interpretability through a...
Molecular features of traditional Chinese medicine syndrome evolution in chronic liver diseases: a dynamic network biomarker analysis
June 2026
To elucidate the biological basis of traditional Chinese medicine (TCM) syndromes from the perspective of “same syndrome, different diseases” in patients with chronic hepatitis B (CHB), liver cirrhosis...
From pulse to pixel: artificial intelligence-enhanced pulse diagnosis for cardiovascular diseases
June 2026
Traditional Chinese medicine (TCM) pulse diagnosis is a non-invasive approach used to infer cardiovascular status, but its interpretation is relatively subjective, limiting reproducibility and diagnostic...
The macro, meso, and micro dimensions of Yin-Yang theory in traditional Chinese medicine: a three-level analysis of Yin and Yang
June 2026
Yin-Yang theory is one of the core components of the foundational theory of traditional Chinese medicine (TCM), yet its classification as philosophical or scientific has long been controversial. To...
Deep learning for subtype recognition of Yang deficiency tongue images in traditional Chinese medicine
June 2026
To address the lack of fine-grained clinical recognition for specific Yang deficiency syndrome subtypes and the limitations of conventional object detection models in extracting irregular, low-contrast...
Facial and tongue features in traditional Chinese medicine for coronary artery stenosis warning and their association chain with cardiac biomarkers
June 2026
To explore whether digital facial and tongue diagnostic technologies can support the assessment of coronary heart disease (CHD) patients for coronary artery stenosis severity, and examine potential...
Comparative evaluation of Mamdani and Takagi-Sugeno fuzzy systems for predicting peripheral vascular resistance from photoplethysmogram signals using Persian medicine pulsology
June 2026
To perform a comparative evaluation of Mamdani and Takagi-Sugeno (TS) fuzzy inference systems for predicting peripheral vascular resistance from photoplethysmogram (PPG) signals, incorporating diagnostic...
CMM-EmbedCluster: a clustering framework for Chinese materia medica based on large language model and Chinese materia medica property theory
June 2026
This study proposes a clustering framework for Chinese materia medica (CMM) based on a large language model (LLM), aiming to explore potential compatibility patterns among CMMs from the semantic perspective...
Interdisciplinary integration and development trends of intelligent diagnosis in traditional Chinese medicine: a topic evolution analysis
March 2026
To systematically characterize the developmental trajectory and interdisciplinary integration of intelligent diagnosis in traditional Chinese medicine (TCM) through quantitative topic evolution analysis,...
Multi-label fundus disease classification using dual-branch deep learning: an intelligent diagnosis framework inspired by traditional Chinese medicine Five Wheels theory
March 2026
To develop a dual-branch deep learning framework for accurate multi-label classification of fundus diseases, addressing the key limitations of insufficient complementary feature extraction and inadequate...
Integrated network pharmacology and experimental validation for identification of mechanism of icariin targeting PLK1 in inhibiting hepatocellular carcinoma
March 2026
To systematically elucidate the molecular mechanisms and core targets underlying the anti-hepatocellular carcinoma (HCC) effects of icariin through integrated network pharmacology and experimental ...
Exploring the mechanism of myofascial trigger points deactivation by Tuina via the TGF-β1/Smad3 signaling pathway
March 2026
To investigate whether Tuina alleviates fibrotic symptoms in myofascial trigger points (MTrPs) by regulating transforming growth factor (TGF)-β1/Smad3 signaling pathway, thereby deactivating these ...
Attenuation of esophageal precancerous lesions in mice by Banxia Xiexin Decoction through gut microbiota modulation
March 2026
To investigate the microbial mechanisms of Banxia Xiexin Decoction (半夏泻心汤, BXXXD) in the treatment of esophageal precancerous lesions....
Ameliorative effects of Ayurvedic Latakaranja vati on dehydroepiandrosterone-induced polycystic ovarian syndrome in rats via inhibition of pro-inflammatory cytokines and oxidative stress
March 2026
To evaluate the therapeutic potential and underlying mechanism of Latakaranja vati (LV) in dehydroepiandrosterone (DHEA)-induced polycystic ovarian syndrome (PCOS) in female Wistar rats through integrated...
Fine-Med-Mental-T&P: a dual-track approach for high-quality instructional datasets of mental disorders in traditional Chinese medicine
March 2026
To investigate methods for constructing a high-quality instructional dataset for traditional Chinese medicine (TCM) mental disorders and to validate its efficacy....
Knowledge graph-enhanced long-tail learning approach for traditional Chinese medicine syndrome differentiation
March 2026
To address the dual challenges of long-tail distribution and feature sparsity in traditional Chinese medicine (TCM) syndrome differentiation within real clinical settings, we propose a data-efficient...
A machine learning-based depression recognition model integrating spirit-expression features from traditional Chinese medicine
March 2026
To develop a depression recognition model by integrating the spirit-expression diagnostic framework of traditional Chinese medicine (TCM) with machine learning algorithms. The proposed model seeks to...
Association of traditional Chinese medicine syndromes with blood lipid profiles and cardiovascular prognosis in post-percutaneous coronary intervention atherosclerotic cardiovascular disease patients: a prospective cohort study
March 2026
Patients with atherosclerotic cardiovascular disease (ASCVD) following percutaneous coronary intervention (PCI) are classified as very-high-risk individuals in cardiovascular disease (CVD) risk stratification....
QingNangTCM: a parameter-efficient fine-tuning large language model for traditional Chinese medicine
March 2026
To develop QingNangTCM, a specialized large language model (LLM) tailored for expert-level traditional Chinese medicine (TCM) question-answering and clinical reasoning, addressing the scarcity of domain-specific...
Clinical decision and prescription generation for diarrhea in traditional Chinese medicine based on large language model
March 2026
To develop a clinical decision and prescription generation system (CDPGS) specifically for diarrhea in traditional Chinese medicine (TCM), utilizing a specialized large language model (LLM), Qwen-TCM-Dia,...
Protection of morusin against lipopolysaccharide-induced acute liver injury through gut microbiota modulation and anti-inflammatory effects in mice
December 2025
To investigate the protective effects of morusin on lipopolysaccharide (LPS)-induced acute liver injury in mice and its underlying mechanisms....
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