Protection of morusin against lipopolysaccharide-induced acute liver injury through gut microbiota modulation and anti-inflammatory effects in mice
December 2025
To investigate the protective effects of morusin on lipopolysaccharide (LPS)-induced acute liver injury in mice and its underlying mechanisms....
Mechanisms of Chinese herbal medicine in modulating gut microbiota on primary open-angle glaucoma: a study based on data mining, network pharmacology, and Mendelian randomization
December 2025
To elucidate the potential mechanisms by which Chinese herbal medicine (CHM) regulates gut microbiota (GM) to influence the development of primary open-angle glaucoma (POAG)....
Mechanism prediction and experimental verification of Maxing Shigan Decoction against influenza A virus infection based on UPLC-MS/MS and network pharmacology
December 2025
To investigate the chemical compositions of Maxing Shigan Decoction (麻杏石甘汤, MXSGD) and elucidate its anti-influenza A virus (IAV) mechanism from prediction to validation....
Traditional Chinese medicine-based phytotherapeutics for junk food-induced obesity and metabolic dysfunction
December 2025
Obesity driven by high-sugar and high-fat dietary patterns has become a major global health challenge and is closely associated with metabolic syndrome, diabetes, and cardiovascular disorders. Growing...
The study of traditional Chinese medicine five-element music therapy for depression: a bibliometric analysis
December 2025
To systematically analyze the research status, highlights, and advancements of five-element music therapy (FEMT) in intervening depression with bibliometric methods....
Quantitative research on tongue diagnosis in traditional Chinese medicine for obstructive coronary artery disease: a computational analysis based on multimodal feature fusion
December 2025
To investigate morphological differences between obstructive and non-obstructive coronary artery disease (CAD) patients using computer-aided image analysis, and identify color and texture features for...
Unveiling core acupoints in acupuncture treatment for primary depressive disorder: integrating data mining and network acupuncture-based analysis
December 2025
To identify core acupoint patterns and elucidate the molecular mechanisms of acupuncture for primary depressive disorder (PDD) through data mining and network analysis....
Mitigation of inflammation and oxidative stress by sarsasapogenin in complete Freund’s adjuvant-induced arthritis: evidence from in silico and in vivo studies
December 2025
To evaluate the anti-arthritic efficacy of sarsasapogenin (SG) alone and in combination with the corticosteroid fluticasone (FC) in a rat model of rheumatoid arthritis (RA), which was induced by complete...
Facial color-preserving generative adversarial network-based privacy protection of facial diagnostic images in traditional Chinese medicine
December 2025
To develop a facial image generation method based on a facial color-preserving generative adversarial network (FCP-GAN) that effectively decouples identity features from diagnostic facial complexion...
Configuration of complex traditional Chinese medicine prescriptions using digit topology circles
December 2025
To configure the complex traditional Chinese medicine (TCM) prescription using digit topology circle and to derive digit topology circle....
Phenomics of traditional Chinese medicine 2.0: the integration with digital medicine
September 2025
Modern western medicine typically focuses on treating specific symptoms or diseases, and traditional Chinese medicine (TCM) emphasizes the interconnections of the body’s various systems under external...
Bone protective potential of Nelumbo nucifera Gaertn. seed hydroalcoholic extract on ovariectomy-induced osteoporosis in Wistar rats via ER/OPG/RANKL signaling pathway
September 2025
To investigate the bone-protective potential of Nelumbo nucifera Gaertn. seed hydroalcoholic extract (NNHE) in an ovariectomized (OVX) rat model by modulating the estrogen receptor/osteoprotegerin/receptor...
A lung cancer early-warning risk model based on facial diagnosis image features
September 2025
To explore the feasibility of constructing a lung cancer early-warning risk model based on facial image features, providing novel insights into the early screening of lung cancer....
Effects of Zuogui Jiangtang Yishen Formula in regulating the NLRP3/caspase-1/GSDMD signaling axis on pyroptosis in rats with diabetic kidney disease
September 2025
To investigate the effects of Zuogui Jiangtang Yishen Formula (左归降糖益肾方, ZGJTYSF) in regulating the nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)/caspase-1/gasdermin D (GSDMD)...
In silico evaluation of hsa-miR-125a-5p and hsa-miR-125b-5p as potential biomarkers for monitoring acupuncture treatment in rheumatoid arthritis
September 2025
To perform an in silico bioinformatics analysis to identify differentially expressed microRNAs (miRNAs) implicated in rheumatoid arthritis (RA) pathogenesis and evaluate their potential as biomarkers...
Reviving classical Bawl (urine) diagnostics in Unani medicine via artificial intelligence and digital tools: toward integrative informatics for traditional systems
September 2025
In Unani medicine, Bawl (urine) is recognized as a key diagnostic tool, with humoural imbalances assessed via parameters like color, consistency, sediment, clarity, froth, odor, and volume. This conceptual...
Traditional Chinese medicine in lupus nephritis: mechanistic insights and integrative therapeutic strategies
September 2025
To review and synthesize preclinical and clinical evidence regarding traditional Chinese medicine (TCM) formulations and bioactive herbal compounds in lupus nephritis (LN), and to identify direction...
Efficacy and safety of the tonifying spleen and reinforcing Qi therapy combined with thyroid hormone in Hashimoto’s hypothyroidism: a systematic review and meta-analysis
September 2025
To evaluate the effectiveness and safety of the tonifying spleen and reinforcing Qi (TSRQ) therapy combined with thyroid hormone replacement therapy (THRT) for treating Hashimoto’s hypothyroidism....
Effects of moxibustion at Huantiao (GB30) acupoint on nerve regeneration in rats with sciatic nerve injury
September 2025
To observe the effects of moxibustion at Huantiao (GB30) acupoint on nerve repair, regeneration, and function in rats with sciatic nerve injury (SNI), and explore the possible mechanism of SNI improvement...
Shanxiangyuanye (Turpiniae Folium) for diabetic complications: chemical constituents and therapeutic potential
September 2025
To analyze the chemical constituents of Shanxiangyuanye (Turpiniae Folium) through liquid chromatography-tandem mass spectrometry (LC-MS/MS) method, and to evaluate their anti-oxidant, hypoglycemic,...
Advances and prospects of the integration of multi-omics and artificial intelligence in traditional Chinese medicine research
September 2025
To map the research hotspots, developmental trends, and existing challenges in the integration of artificial intelligence (AI) with multi-omics in traditional Chinese medicine (TCM) through comprehensive...
Clinical efficacy of fecal microbiota transplantation based on syndrome element differentiation principle in the treatment of type 2 diabetes mellitus
September 2025
To investigate the therapeutic efficacy and potential mechanisms of fecal microbiota transplantation (FMT) in patients with type 2 diabetes mellitus (T2DM), and to preliminarily identify the traditional...
Development and validation of a quality appraisal tool for case reports in traditional Chinese medicine using the Delphi method
June 2025
To develop a quality appraisal tool for case reports in traditional Chinese medicine (TCM) based on their characteristics....
Correlation analysis between facial feature-based traditional Chinese medicine inspection of spirit classification and Beck Depression Inventory score
June 2025
To determine the correlation between traditional Chinese medicine (TCM) inspection of spirit classification and the severity grade of depression based on facial features, offering insights for intelligent...
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