The Human-AI Frontier: An in-depth exploration of physicians' apprehension and Outlook Towards Artificial Intelligence in gastroenterology healthcare
October 2025
Recent advances in artificial intelligence (AI) have transformed healthcare, offering potential in diagnosis, treatment, and patient management in gastroenterology. Understanding physicians' attitudes...
Enhanced Liver Cancer Detection: Leveraging Pre-processing Techniques for 3D CT Volumes
Available online 23 August 2025
Accurate extraction and segmentation of the liver from medical images remain challenging due to the organ's irregular shape, similar intensity values to adjacent structures, variable contrast levels,...
Mutational Analysis of Exon 14 and 15 of the APC Gene in Esophageal Squamous Cell Carcinoma in Mthatha-South Africa: A Cross-Sectional Study
Available online 21 August 2025
Esophageal cancer is a major public health challenge in the Eastern Cape region of South Africa. Although changes in the APC gene are frequently implicated in various forms of cancer, few studies have...
Pharmacotherapy challenges in HIV patient with Plummer-Vinson Syndrome
July 2025
Plummer-Vinson Syndrome (PVS) is a rare condition characterized by the classic triad of dysphagia, iron-deficiency anemia or long-standing anemia, and esophageal web. We present a case of a 38-year-old...
Ilaprazole: Distinctive pharmacokinetic and pharmacodynamic properties among proton pump inhibitors
July 2025
Ilaprazole is a new proton pump inhibitor (PPI) that provides effective and sustained intragastric acid suppression. As PPIs are foundational medications in the treatment of acid-related disorders,...
Identification of key genes and pathways in the following pancreatic ductal adenocarcinoma (PDAC) using integrated bioinformatics analysis
July 2025
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, and understanding its molecular mechanisms is critical for improving diagnosis and treatment. This study analyzed microarray datasets...
Upper GI endoscopy in children with Helicobacter pylori Infection: Insights from a six-year retrospective review
July 2025
Helicobacter pylori (H. pylori) is a prevalent bacterial infection acquired primarily during childhood, particularly in regions with poor sanitation and overcrowding. In Bangladesh, limited data exists...
Endoscopic marginal assessment of fixed colorectal polyps accurately predicts complete resection after cold snare polypectomy:a prospective single-center observational study
July 2025
This study aimed to ascertain the effectiveness of using fixed cold snare polypectomy (CSP) specimens, accompanied by endoscopic assessment, in predicting complete resection outcomes....
When the gut Speaks: The hidden toll of irritable bowel syndrome on body and mind
July 2025
Irritable bowel syndrome (IBS) is a multifaceted gastrointestinal disorder that transcends the gut, affecting the physical, psychological, and social well-being of millions worldwide. Despite its prevalence,...
Prevalence of sleep apnea amongst the population of Saudi Arabia
July 2025
This cross-sectional study aimed to assess the prevalence of sleep apnea among the gastritis population in Saudi Arabia and explore its associations with sociodemographic factors, health conditions,...
Prospects of clinical trials for novel therapeutic approaches in celiac disease
July 2025
Celiac disease (CD) is a chronic a multifactorial immune-mediated systemic inflammatory disease of the small intestine caused by genetic and environmental factors, elicited by the ingestion of dietary...
Exploring the Effects of Reflexology on Gastrointestinal Symptoms in Type-2 Diabetic Patients: A Quasi-Experimental Study
Available online 18 July 2025
Type 2 diabetes is a growing global health concern, often leading to gastrointestinal complications that impact quality of life. Reflexology, a non-invasive therapy, may help alleviate these symptoms,...
The Frequency and Characteristics of Inflammatory Bowel Disease in Pediatric Patients with Hirschsprung's Disease: A Case-Control Study
Available online 4 June 2025
Hirschsprung disease is associated with enterocolitis and inflammatory bowel disease (IBD) as it affects bowel innervation from birth. This study is about the evaluation of IBD in children with diagnosed...
The digestive system under microgravity environment: Changes, mechanisms and the prospects of the future
April 2025
In recent years, the space industry has continued to improve and develop, and human beings have been staying in space for longer periods while facing the challenges of microgravity to human life. The...
Colorectal cancer spectrum: From subtypes and epidemiology to oncotherapies
April 2025
Colorectal cancer (CRC) has an incidence rate of 10 % and is the third most common cause of mortality worldwide, following breast and lung cancer. The clinical symptoms of CRC appear in the last phases...
Alcohol-associated liver disease: A review
April 2025
Alcohol-associated Liver Disease (ALD) is a collection of liver disorders caused by prolonged and excessive alcohol consumption, ranging from fatty liver alterations to fibrosis and cirrhosis. This...
Esophageal adenocarcinoma with unexpectedly high AFP levels: A diagnostic challenge
April 2025
Alpha-fetoprotein (AFP)-producing Esophageal Adenocarcinoma (EAC) is an extremely rare entity with only a few cases reported till date. Reporting the first case of AFP producing EAC from Pakistan....
Extensive recurrence of colon adenocarcinoma: A case of cutaneous metastasis to the legs and its clinical implication
April 2025
The rate of cutaneous metastases in cancer patients overall is reported at highly variable rates, presenting in up to 5% of visceral malignancies. Colorectal carcinoma most commonly metastasizes to...
Ultrasonic diagnosis of hepatic and splenic infarction: A case report
April 2025
It is extremely rare for both the liver and spleen to experience infarction simultaneously. Hepatic and splenic infarction is a severe condition, and early diagnosis has a significant impact on the...
Automated liver segmentation from CT images using modified ResUNet
April 2025
The Segmentation of liver from computed tomography (CT) images is a critical task in medical research particularly when employing deep learning methods. Most doctors prefer to use Computed tomography...
Diagnostic efficacy of computed tomography angiography for acute gastrointestinal bleeding
April 2025
Computed tomography angiography (CTA) is the radiologic test for acute gastrointestinal bleeding (GIB). We aimed to (1) identify the clinical factors associated with (a) positive CTA findings, (b) positive...
Prevalence of peptic ulcer disease and its associated factors in Jeddah Saudi Arabia
January 2025
Peptic ulcer disease's (PUD) global significance, emphasizing its health burdens and associations with factors like Helicobacter pylori infection and lifestyle habits. The need for comprehensive approaches...