The digestive system under microgravity environment: Changes, mechanisms and the prospects of the future
April 2025
In recent years, the space industry has continued to improve and develop, and human beings have been staying in space for longer periods while facing the challenges of microgravity to human life. The...
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Colorectal cancer spectrum: From subtypes and epidemiology to oncotherapies
April 2025
Colorectal cancer (CRC) has an incidence rate of 10 % and is the third most common cause of mortality worldwide, following breast and lung cancer. The clinical symptoms of CRC appear in the last phases...
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Alcohol-associated liver disease: A review
April 2025
Alcohol-associated Liver Disease (ALD) is a collection of liver disorders caused by prolonged and excessive alcohol consumption, ranging from fatty liver alterations to fibrosis and cirrhosis. This...
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Esophageal adenocarcinoma with unexpectedly high AFP levels: A diagnostic challenge
April 2025
Alpha-fetoprotein (AFP)-producing Esophageal Adenocarcinoma (EAC) is an extremely rare entity with only a few cases reported till date. Reporting the first case of AFP producing EAC from Pakistan....
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Extensive recurrence of colon adenocarcinoma: A case of cutaneous metastasis to the legs and its clinical implication
April 2025
The rate of cutaneous metastases in cancer patients overall is reported at highly variable rates, presenting in up to 5% of visceral malignancies. Colorectal carcinoma most commonly metastasizes to...
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Ultrasonic diagnosis of hepatic and splenic infarction: A case report
April 2025
It is extremely rare for both the liver and spleen to experience infarction simultaneously. Hepatic and splenic infarction is a severe condition, and early diagnosis has a significant impact on the...
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Automated liver segmentation from CT images using modified ResUNet
April 2025
The Segmentation of liver from computed tomography (CT) images is a critical task in medical research particularly when employing deep learning methods. Most doctors prefer to use Computed tomography...
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Diagnostic efficacy of computed tomography angiography for acute gastrointestinal bleeding
April 2025
Computed tomography angiography (CTA) is the radiologic test for acute gastrointestinal bleeding (GIB). We aimed to (1) identify the clinical factors associated with (a) positive CTA findings, (b) positive...
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Ilaprazole: Distinctive Pharmacokinetic and Pharmacodynamic Properties Among Proton Pump Inhibitors
Available online 9 April 2025
Ilaprazole is a new proton pump inhibitor (PPI) that provides effective and sustained intragastric acid suppression. As PPIs are foundational medications in the treatment of acid-related disorders,...
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Pharmacotherapy Challenges in HIV patient with Plummer-Vinson Syndrome
Available online 11 March 2025
Plummer-Vinson Syndrome (PVS) is a rare condition characterized by the classic triad of dysphagia, iron-deficiency anemia or long-standing anemia, and esophageal web. We present a case of a 38-year-old...
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Prevalence of peptic ulcer disease and its associated factors in Jeddah Saudi Arabia
January 2025
Peptic ulcer disease's (PUD) global significance, emphasizing its health burdens and associations with factors like Helicobacter pylori infection and lifestyle habits. The need for comprehensive approaches...
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Subcutaneous panniculitis as complication of valproate-induced pancreatitis
January 2025
Medications and drugs constitute a well-known etiology of pancreatitis. Rare signs and symptoms of the disease can occur. We present a case of pancreatitis caused by valproic acid and that was complicated...
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Systemic immune-inflammation index: Unveiling the diagnostic potential in ulcerative colitis through a comprehensive systematic review and meta-analysis
January 2025
Ulcerative colitis (UC) is a chronic inflammatory bowel disease with unpredictable colon and rectum inflammation episodes. Evaluating disease activity is essential for effective management. The systemic...
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Liver lobes and cirrhosis: Diagnostic insights from lobar ratios
January 2025
Liver cirrhosis is the formation of abnormal nodular structure and fibrosis. Globally it accounts for 4 % of all deaths. Alcohol, viral hepatitis, and non-alcoholic fatty liver disease are the most...
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A rare case of hemobilia caused by acute cholecystitis with an underlying gallbladder aneurysm
January 2025
We present a case of a patient who presented with upper gastrointestinal bleeding, obstructive jaundice and bacteremia, of which the underlying cause turned out to be hemobilia from acute cholecystitis...
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The complexity of mucosal damage in gastroesophageal airway reflux disease: A molecular perspective
January 2025
Gastroesophageal airway reflux disease (GARD) refers to a class of diseases in which the contents of the digestive system reflux into esophagus, the upper and lower airways, mouth, ear and nose et al.,...
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Human umbilical cord derived-mesenchymal stem cells alleviate lipid metabolism disturbances of hepatocytes via mitochondrial transport
January 2025
To explore the effect and mechanism of human umbilical cord derived-mesenchymal stem cells (UC-MSCs) on improving lipid metabolism disorders in vitro....
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The best beginning, a smooth process, and a bright future of gastroenterology & endoscopy
January 2025
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Internal Hernia in a Patient with Chylous Ascites: A Case Report
Available online 17 January 2025
Chylous ascites is a rare medical condition characterized by the leakage of chylous fluid from the lymphatic system into the abdominal cavity. Suppose the patient has a history of abdominal surgery,...
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Celiac disease with exocrine pancreatic insufficiency and dilated cardiomyopathy in pediatric patient: A rare case report
October 2024
There are several clinical manifestations of celiac disease, an autoimmune enteropathy caused by gluten intake, including extra-intestinal and gastrointestinal symptoms. Although it is linked to dilated...
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Endoscopic and stool-based colorectal cancer screening coverage among US veterans: A survey analysis using 2021 Behavioral Risk Factor Surveillance System (BRFSS) data
October 2024
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths for the overall US population, with over 153,000 new cases annually. It is one the most diagnosed cancers in veterans and...
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The dual role of LncRNAs in hepatocellular carcinoma: Friend and foe
October 2024
In eukaryotes, RNA molecules called long non-coding RNAs (LncRNAs) have been found. Molecules that exceed 200 base pairs in length are incapable of coding for proteins. Studying the function of LncRNAs...
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Endoscopic management of ingested foreign bodies in children: A tertiary center experience in Bangladesh
October 2024
To examine the features of foreign body ingestion and evaluate the effectiveness of endoscopic therapy for foreign body ingestion in Bangladeshi children....
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Effective non-surgical treatment of hemorrhoids with sclerosing foam and novel injection device
October 2024
To determine the effectiveness of a novel protocol to treat patients with hemorrhoidal disease....
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