Most Downloaded Articles

Open access

ISSN: 2707-3688
e-ISSN: 2950-175X

Study on the application of Aloe vera in cosmetology and clinical treatment of skin diseases

The medicinal value of Aloe vera (AV) has been continuously explored and utilized in recent years, becoming a research hotspot. Some basic studies have found that AV had cosmetic effects such as whitening,...

Research progress on the application of Pleuropterus multiflorus in the treatment of androgenetic alopecia

Androgenetic alopecia (AGA) is the most common form of hair loss, affecting approximately 21.3% of men and 6% of women in China, with an increasing trend among younger individuals. Currently, finasteride...

Vitamins strategies for psoriasis: An update on current scientific evidence

Psoriasis is an aggressive chronic skin disorder that requires various therapies such as topical, oral, and occasionally, subcutaneous, or intravenous. In contrast, vitamins have more significant evidence...

The transformative power of artificial intelligence in pharmaceutical manufacturing: Enhancing efficiency, product quality, and safety

The pharmaceutical manufacturing industry transforms through artificial intelligence (AI) by implementing process improvements along with productivity enhancements and product quality improvements....

Exploring synergistic effects of bioactive compounds and pharmaceuticals in therapeutic applications

Synergy arises when the combined effect of multiple agents exceeds the sum of their individual activities. Pharmacological and bioactive chemical synergy offers a promising approach to enhance therapeutic...

Deciphering the anti-senescence immune paradigm: Kidney yin-yang equilibrium in traditional Chinese medicine

In traditional Chinese medicine (TCM), the kidney is considered the "innate foundation", and the abundance or diminution of its essence directly affects the growth, development, physical form, and physiological...

Gut–brain axis in neurological disorders: mechanistic links and regulatory role of Chinese herbal medicines

The gut–brain axis (GBA) is a bidirectional communication network integrating neural, immune, endocrine, and metabolic pathways that link the gastrointestinal tract and the central nervous system. Increasing...

Machine learning models for predicting pharmacokinetics and pharmacodynamics: A step toward personalized dosing

Machine learning (ML) has become increasingly integrated within pharmacokinetics (PK) and pharmacodynamics (PD) modeling in recent years, and represents a new paradigm in precision medicine, enabling...

Design and optimization of polyherbal tablets for anti-inflammatory therapy: A design of experiment approach with in vitro and in vivo evaluation

To develop and optimize polyherbal tablets containing Terminalia chebula, Moringa oleifera, and Ocimum sanctum as a multi-targeted therapeutic approach for the management of chronic inflammatory di...

Therapeutic approaches to dyslipidaemia in Unani medicine: a narrative review

Dyslipidaemia is one of the most common metabolic disorders, strongly linked with cardiovascular disease, obesity, and other components of metabolic syndrome. In Unani medicine, this condition is understood...

From traditional herb to modern therapeutics: phytochemistry, pharmacology, toxicology, and clinical translation challenges of Cyperus rotundus L

Cyperus rotundus L. (C. rotundus.), widely distributed in tropical and temperate regions, is a perennial herb with a long history of application in traditional medical systems for treating emotional...

Recent advances in artificial intelligence for melanoma: A review of history, models, datasets, applications, and ethical and legal considerations

Melanoma is one of the most lethal and aggressive forms of skin cancer, often presenting as evolving pigmented lesions. This review aims to examine melanoma from a holistic perspective by evaluating...

Influence of extraction techniques and solvent polarity on phytochemical yield: A comprehensive analytical study of Malvastrum coromandelianum (L.) Garcke

Malvastrum coromandelianum (L.) Garcke, (Family: Malvaceae) is traditionally valued for its therapeutic properties. This study aimed to evaluate the phytochemical composition and bioactivities of different...

Traditional uses, chemical composition and pharmacological properties of genus Crotalaria

The plants of genus Crotalaria are widely employed in traditional folk medicine to address various ailments. Extracts from these plants have been reported to exhibit diverse pharmacological properties,...

Phytochemical profiles, biological activities and medicinal importance of Aloe vera L.: A review

Aloe vera (Av) is revered in Ayurveda as the "wand of heaven" or "heaven's blessing" and precisely the "silent healer". This herbaceous plant belongs to Asphodelaceae family, previously classified as...

Study on the potential medical beauty efficacy screening of acetyl hexapeptide-8 and the mechanism of regulating collagen regeneration

Acetyl hexapeptide-8 (AH-8) is a synthetic polypeptide that can promote collagen regeneration; however, the underlying mechanism of this promoting effect and other potential medical beauty efficacy...

Antidiabetic activity of bioactive fractions from Momordica cymbalaria Fenzl ex Naudin leaves: In vitro, in silico and in vivo evaluation

This study evaluated the antidiabetic activity of Momordica cymbalaria Fenzl ex Naudin (MC) leaf fractions, a traditionally used remedy in southern India, through comprehensive in vitro, in silico,...

A scoping review of five selected underutilized medicinal plants of Sri Lanka: Focusing on ethnobotany, phytochemistry and bioactivities, and evaluation of their potential for novel herbal product development

Ageratum conyzoides L., Artocarpus gomezianus Wall. ex Trécul, Euphorbia hirta L., Plectranthus zeylanicus Benth., and Piper sarmentosum Roxb. have long been utilized in traditional medical practices,...

Review on application and development of pharmacogenomics of adverse drug reactions

Adverse drug reactions (ADRs) are a significant public health issue, contributing substantially to patient morbidity and mortality. The growing accessibility of genomic technologies has greatly advanced...

Review on clinical diagnosis, pathogenesis and therapeutic strategies of drug-induced liver injury

Drug-induced liver injury (DILI) is a severe adverse reaction caused by various drugs and their metabolites, with complex clinical manifestations, and severe cases may progress to acute liver failure...

Synthesis of a novel C46 ceramide and its skin barrier repair effect verified by molecular dynamics and cellular assays

Ceramides play a critical role in skin barrier function. Here, we synthesized a novel long-chain ceramide, C46 EOP, via a sustainable catalyst-free route and elucidated its molecular mechanisms and...

Formulation and evaluation of carbamazepine loaded ethosomal nasal in-situ gel for brain targeted drug delivery

This study aimed to develop a novel intranasal drug delivery system for carbamazepine, an antiepileptic drug, to enhance its therapeutic efficacy through targeted and sustained delivery. The goal was...

Bibliometric analysis of research on plant exosomes/extracellular vesicles: current status, hotspots, and trends

This study performed a comprehensive bibliometric analysis on 1373 valid publications of plant exosomes/extracellular vesicles from 2010 to 2026, retrieved from CNKI, WoSCC and PubMed and screened manually....

WRKY-mediated regulation of secondary metabolite production in medicinal plants

WRKY transcription factors represent a quintessential regulatory clade involved in plant growth, stress adaptation, and secondary metabolic processes. Extensive research has elucidated that WRKY proteins...

Antimicrobial mechanism of Artemisia argyi essential oil against Carbapenem-resistant Escherichia coli by metabolomics analysis

To investigate the antibacterial activity, mechanism of action, and wound healing-promoting effect of Artemisia argyi essential oil (AAEO) against carbapenem-resistant Escherichia coli CREO-76....

Stay Informed

Register your interest and receive email alerts tailored to your needs. Sign up below.