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ISSN: 2707-3688
e-ISSN: 2950-175X

Research progress on the application of Pleuropterus multiflorus in the treatment of androgenetic alopecia

Androgenetic alopecia (AGA) is the most common form of hair loss, affecting approximately 21.3% of men and 6% of women in China, with an increasing trend among younger individuals. Currently, finasteride...

Study on the application of Aloe vera in cosmetology and clinical treatment of skin diseases

The medicinal value of Aloe vera (AV) has been continuously explored and utilized in recent years, becoming a research hotspot. Some basic studies have found that AV had cosmetic effects such as whitening,...

Deciphering the anti-senescence immune paradigm: Kidney yin-yang equilibrium in traditional Chinese medicine

In traditional Chinese medicine (TCM), the kidney is considered the "innate foundation", and the abundance or diminution of its essence directly affects the growth, development, physical form, and physiological...

Vitamins strategies for psoriasis: An update on current scientific evidence

Psoriasis is an aggressive chronic skin disorder that requires various therapies such as topical, oral, and occasionally, subcutaneous, or intravenous. In contrast, vitamins have more significant evidence...

The transformative power of artificial intelligence in pharmaceutical manufacturing: Enhancing efficiency, product quality, and safety

The pharmaceutical manufacturing industry transforms through artificial intelligence (AI) by implementing process improvements along with productivity enhancements and product quality improvements....

Exploring synergistic effects of bioactive compounds and pharmaceuticals in therapeutic applications

Synergy arises when the combined effect of multiple agents exceeds the sum of their individual activities. Pharmacological and bioactive chemical synergy offers a promising approach to enhance therapeutic...

Gut–brain axis in neurological disorders: mechanistic links and regulatory role of Chinese herbal medicines

The gut–brain axis (GBA) is a bidirectional communication network integrating neural, immune, endocrine, and metabolic pathways that link the gastrointestinal tract and the central nervous system. Increasing...

Review on clinical diagnosis, pathogenesis and therapeutic strategies of drug-induced liver injury

Drug-induced liver injury (DILI) is a severe adverse reaction caused by various drugs and their metabolites, with complex clinical manifestations, and severe cases may progress to acute liver failure...

Machine learning models for predicting pharmacokinetics and pharmacodynamics: A step toward personalized dosing

Machine learning (ML) has become increasingly integrated within pharmacokinetics (PK) and pharmacodynamics (PD) modeling in recent years, and represents a new paradigm in precision medicine, enabling...

Traditional uses, chemical composition and pharmacological properties of genus Crotalaria

The plants of genus Crotalaria are widely employed in traditional folk medicine to address various ailments. Extracts from these plants have been reported to exhibit diverse pharmacological properties,...

Recent advances in artificial intelligence for melanoma: A review of history, models, datasets, applications, and ethical and legal considerations

Melanoma is one of the most lethal and aggressive forms of skin cancer, often presenting as evolving pigmented lesions. This review aims to examine melanoma from a holistic perspective by evaluating...

Ethnobotanical survey and evaluation of antioxidant and angiotensin-converting enzyme inhibitory activities of selected medicinal plants

The pathophysiology of several diseases, including hypertension, is linked to oxidative stress. Natural antioxidants play a crucial role in maintaining the balance between pro- and antioxidant levels....

Design and optimization of polyherbal tablets for anti-inflammatory therapy: A design of experiment approach with in vitro and in vivo evaluation

To develop and optimize polyherbal tablets containing Terminalia chebula, Moringa oleifera, and Ocimum sanctum as a multi-targeted therapeutic approach for the management of chronic inflammatory di...

Cancer-induced bone pain: spinal cord mechanisms and traditional Chinese medicine treatment

Cancer-induced bone pain (CIBP) is a severe, intolerable, and complex pain condition caused by the primary bone tumor or bone metastasis. CIBP is a combination of complex pain states such as persistent...

The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough

Coughing as the main symptom of a chronic cough is a persistent respiratory disease that poses a substantial challenge to Western medicine and traditional Chinese medicine (TCM). The Large Intestine...

Gut–brain–immune crosstalk in drug-resistant epilepsy: mechanisms and therapeutic perspectives

Epilepsy is one of the most prevalent neurological disorders worldwide, affecting approximately 50–52 million individuals. Approximately 30% of patients develop drug-resistant epilepsy (DRE) despite...

WRKY-mediated regulation of secondary metabolite production in medicinal plants

WRKY transcription factors represent a quintessential regulatory clade involved in plant growth, stress adaptation, and secondary metabolic processes. Extensive research has elucidated that WRKY proteins...

Therapeutic approaches to dyslipidaemia in Unani medicine: a narrative review

Dyslipidaemia is one of the most common metabolic disorders, strongly linked with cardiovascular disease, obesity, and other components of metabolic syndrome. In Unani medicine, this condition is understood...

From traditional herb to modern therapeutics: phytochemistry, pharmacology, toxicology, and clinical translation challenges of Cyperus rotundus L

Cyperus rotundus L. (C. rotundus.), widely distributed in tropical and temperate regions, is a perennial herb with a long history of application in traditional medical systems for treating emotional...

Study on the potential medical beauty efficacy screening of acetyl hexapeptide-8 and the mechanism of regulating collagen regeneration

Acetyl hexapeptide-8 (AH-8) is a synthetic polypeptide that can promote collagen regeneration; however, the underlying mechanism of this promoting effect and other potential medical beauty efficacy...

Review on application and development of pharmacogenomics of adverse drug reactions

Adverse drug reactions (ADRs) are a significant public health issue, contributing substantially to patient morbidity and mortality. The growing accessibility of genomic technologies has greatly advanced...

Cannabidiol as a modulator of NLRP3 inflammasome: Mechanistic insights and therapeutic potential

Dysregulated activation of the NLRP3 inflammasome is a central driver of chronic inflammatory, neurodegenerative, metabolic, and autoimmune diseases, contributing significantly to the global burden...

Phytochemical profiles, biological activities and medicinal importance of Aloe vera L.: A review

Aloe vera (Av) is revered in Ayurveda as the "wand of heaven" or "heaven's blessing" and precisely the "silent healer". This herbaceous plant belongs to Asphodelaceae family, previously classified as...

An integrative framework for precision medication in hypertension: Applying a dialectical perspective to traditional Chinese and Western medicine

Hypertension is the most common cardiovascular disease. In terms of diagnosis and treatment, Traditional Chinese Medicine (TCM) and Western medicine each have their own strengths, but also have certain...

Integration of network pharmacology and experimental validation to elucidate the mechanism of Moutan cortex against acute lung injury

This study aims to investigate the underlying mechanisms of Moutan Cortex (MC) against acute lung injury (ALI) by integrating network pharmacology, molecular docking and experimental validation in zebrafish...

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