Genomics-based tools for drug discovery and development: From network maps to efficacy prediction
November 2023
Computing technology plays a crucial role in the field of drug discovery and development. With the rapid development of genomics and the improvement of databases, the application of genomics-based tools...
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Optimisation study on the flavonoid extraction process from Abrus precatorius leaves and the comparison of total flavonoid content by HPLC and UV
October 2023
Abrus precatorius is a leguminous plant with high medicinal value. Its leaves are rich in flavonoids. There only are limited reports on the extraction process and quality assessment of total flavonoids...
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Combining single-cell RNA sequencing data and network pharmacology to explore the mechanism of action of Dayuan Yin in the treatment of acute lung injury
December 2023
This study aimed to analyze the usefulness of combined single-cell RNA sequencing data and network pharmacology in understanding the molecular regulation mechanism of Dayuan Yin (DYY) in acute lung...
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Research progress in the regulation of secondary metabolism in medicinal plants by MYB transcription factors
December 2023
MYB transcription factors (MYB TFs)are one of the largest families of transcription factors in plants, which are widely involved in various fields of plant growth and development, and play an important...
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Chloroplast genome of Thesium chinense: The insight into phylogeny of Santalaceae
December 2023
Thesium chinense is an important and commonly used traditional Chinese medicine. The aim of this study is to obtain more bioinformatics from Thesium chinense and to conduct a more comprehensive and...
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Vitamins strategies for psoriasis: An update on current scientific evidence
December 2023
Psoriasis is an aggressive chronic skin disorder that requires various therapies such as topical, oral, and occasionally, subcutaneous, or intravenous. In contrast, vitamins have more significant evidence...
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Research progress on Prunella vulgaris and its monomers in protecting against ulcerative colitis
November 2023
Prunella vulgaris is a traditional Chinese herbal medicine with many pharmacological effects, among which the anti-inflammatory effect is more significant. It is widely reported that Prunella vulgaris...
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Exploring the therapeutic effects of Zingiberis Rhizoma Preparatum (Pao-Jiang) against DSS-induced ulcerative colitis in mice by metabolomics-guided analysis
December 2023
Zingiberis Rhizoma Recens (Sheng-Jiang) is a kind of edible and medicinal plant resource in China. Both Zingiberis Rhizoma Recens and its dried form, Zingiberis Rhizome (Gan-Jiang), have been widely...
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Review of compounds and activities from mangrove Sonneratia genus and their endophytes
November 2023
Sonneratia is an important mangrove plant, and its fruit has been used as traditional medicine and food in southeast China. With recent research focusing on its compounds and activities, an increasing...
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Identifying candidate drugs based on transcriptional landscape associated with triple-negative breast cancer
December 2023
Triple-negative breast cancer (TNBC) is a special type of breast cancer in which ER, PR and HER2 are all negative, characterized by high malignancy, strong invasiveness, and high recurrence rate. It...
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Peptide drugs application in metabolic diseases and discovery strategies
March 2022
Peptides (or polypeptides) are generally defined as those molecules compounded with less than 100 amino acids linked by peptide bonds, and the relative molecular weight is less than 10 000 Da usually....
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Study on the synergistic development of TCM service trade within the GBA
November 2023
This study analyzed the synergistic development of the Traditional Chinese Medicine (TCM) service trade within the Greater Bay Area (GBA) in China, aiming to provide suggestions and references for the...
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Study on the anti-inflammatory activity of chaga mushroom aqueous extract-alcohol precipitate
June 2021
To extract the active ingredient from chaga mushroom (aqueous extract-alcohol precipitates) to study its safety and anti-inflammatory activity....
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Truxillic and truxinic acid derivatives: configuration, source, and bioactivities of natural cyclobutane dimers
September 2020
Natural truxillic and truxinic acid derivatives are interesting cyclobutane dimers, with different stereo conformations formed by the orientation of groups on the cyclobutane. These derivatives are...
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Mangrove soil-derived Streptomyces: an important resource of pharmaceutical active natural products
September 2022
The mangrove soil-derived microbes, especially genus Streptomyces strains, have proven to be a rich source of bioactive secondary metabolites and play a critical role in the development of pharmaceutical...
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Analysis on the treatment of acne by Sanhuang with network pharmacology and experimental research
December 2022
To explore the main active components and potential targets of “Sanhuang Xiexin decoction” (Sanhuang) against acne based on network pharmacology and molecular docking technology, and research the bacteriostatic...
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Dioscoreae persimilis polysaccharide ameliorates DSS-induced ulcerative colitis in mice through modulation of microbiota composition
October 2023
Ulcerative colitis (UC) is a non-specific inflammatory bowel disease that has a high rate of recurrence, development of novel therapeutic approaches with high efficacy and few adverse effects are still...
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Meta-analysis of the impact of pharmaceutical care on the outcome of gestational diabetes
March 2023
Pharmaceutical care is based on pharmacy, effective organization, and the management of drugs and patients throughout the medication process, to promote the scientific and rational use of drugs. This...
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Combination treatment of a deep diabetic toe ulcer with collagenase-santyl dressings and antibiotics: A case report
November 2023
A diabetic foot ulcer is defined as the ulceration of tissues brought on by trauma and some peripheral neurological abnormalities, primarily as a result of the bacterial infection. The infection of...
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A pan-cancer analysis of oncogenic protein tyrosine phosphatase subfamily PTP4As
October 2023
The objective of this study was to conduct a comprehensive pan-cancer analysis of Protein tyrosine phosphatase 4A (PTP4As), specifically PTP4A1, PTP4A2, and PTP4A3, to investigate their aberrant expression,...
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Synthesis, cytotoxicity study of novel bisacridine derivatives and their interaction with c-myc promoter G-quadruplex/i-motif
December 2023
To synthesize novel bisacridine derivatives A1-A4 and study cytotoxicity and their interaction with c-myc G-quadruplex/i-motif DNA....
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Appropriate medical practice—natural forces and medical intervention
March 2021
Medical practice is the most important step in fulfilling the medical purposes of medical theory. Appropriate medical practice not only can help treat and prevent diseases, but also is beneficial to...
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Pharmacognostical study of Croton Crassifolius Geisel
November 2023
Croton Crassifolius Geisel of the genus Croton in the Euphorbia family is a widely distributed herb in South China. It has medicinal value for the treatment of a sore throat, soothing tendons, activating...
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Analysis of clinical drug use and construction of pharmacy service model for children with Kawasaki disease based on integration concept
October 2023
This study aimed to summarize and share the experience of clinical pharmacists in the clinical treatment of children with Kawasaki disease based on the “integration” concept....
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Antiseptic property screening for 18 natural plants and efficiency–toxicity research of Coptis chinensis fermentation
December 2022
This study aimed to compare the antibacterial performance of 18 natural plants against six types of microorganisms that tend to grow in cosmetics and select the best natural antiseptic herbs with low...
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