Vitamins strategies for psoriasis: An update on current scientific evidence
December 2023
Psoriasis is an aggressive chronic skin disorder that requires various therapies such as topical, oral, and occasionally, subcutaneous, or intravenous. In contrast, vitamins have more significant evidence...
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Study on the application of Aloe vera in cosmetology and clinical treatment of skin diseases
December 2024
The medicinal value of Aloe vera (AV) has been continuously explored and utilized in recent years, becoming a research hotspot. Some basic studies have found that AV had cosmetic effects such as whitening,...
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Deciphering the anti-senescence immune paradigm: Kidney yin-yang equilibrium in traditional Chinese medicine
June 2024
In traditional Chinese medicine (TCM), the kidney is considered the "innate foundation", and the abundance or diminution of its essence directly affects the growth, development, physical form, and physiological...
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The transformative power of artificial intelligence in pharmaceutical manufacturing: Enhancing efficiency, product quality, and safety
June 2025
The pharmaceutical manufacturing industry transforms through artificial intelligence (AI) by implementing process improvements along with productivity enhancements and product quality improvements....
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The repair effect of α-ketoglutarate combined with mesenchymal stem cells on osteoarthritis via the hedgehog protein pathway
March 2025
Mesenchymal stem cell (MSC) therapy represents a promising treatment strategy for osteoarthritis (OA). Nevertheless, the therapeutic efficacy of MSCs may be attenuated under conditions of cellular senescence...
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Development of ginger oleoresin-enriched marshmallow candy as a nutraceutical for managing pediatric chemotherapy-induced nausea and vomiting
March 2025
Chemotherapy-induced nausea and vomiting (CINV) significantly impact pediatric cancer patients, affecting treatment adherence and quality of life. This study aimed to develop gingerol-enriched marshmallow...
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Review on application and development of pharmacogenomics of adverse drug reactions
March 2025
Adverse drug reactions (ADRs) are a significant public health issue, contributing substantially to patient morbidity and mortality. The growing accessibility of genomic technologies has greatly advanced...
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Formulation and evaluation of carbamazepine loaded ethosomal nasal in-situ gel for brain targeted drug delivery
March 2025
This study aimed to develop a novel intranasal drug delivery system for carbamazepine, an antiepileptic drug, to enhance its therapeutic efficacy through targeted and sustained delivery. The goal was...
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Genomics-based tools for drug discovery and development: From network maps to efficacy prediction
November 2023
Computing technology plays a crucial role in the field of drug discovery and development. With the rapid development of genomics and the improvement of databases, the application of genomics-based tools...
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The research advance on the theory of Chinese medicine-exterior-interior correlation between the Lung and Large Intestine in the treatment of chronic cough
September 2024
Coughing as the main symptom of a chronic cough is a persistent respiratory disease that poses a substantial challenge to Western medicine and traditional Chinese medicine (TCM). The Large Intestine...
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Study on the factors affecting the competitiveness of biopharmaceutical industry cluster: Evidence from Guangdong and Zhejiang of China
March 2025
This study aims to analyze factors affecting the competitiveness of China's biopharmaceutical industry cluster, offering insights for policymakers and stakeholders, while providing Chinese experience...
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Unravelling the gut-liver axis: The role of gut microbiota-mitochondria interactions in the pathogenesis and management of metabolic-associated fatty liver disease (MAFLD)
March 2025
Metabolic-associated fatty liver disease (MAFLD) has emerged as a prevalent chronic liver disease. Our review of the existing literature reveals that the interplay between gut microbiota, mitochondria,...
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The versatility of apigenin: Especially as a chemopreventive agent for cancer
December 2024
Apigenin, a naturally occurring flavonoid found in fruits and vegetables, has received substantial attention due to its various pharmacological effects, particularly in cancer therapy. This review delves...
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Review of compounds and activities from mangrove Sonneratia genus and their endophytes
November 2023
Sonneratia is an important mangrove plant, and its fruit has been used as traditional medicine and food in southeast China. With recent research focusing on its compounds and activities, an increasing...
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Pharmacognostic studies on three species of Spermacoce
March 2024
To provide a scientific basis for identification of Spermacoce species, including Spermacoce remota Lamarck, Spermacoce exilis (L. O. Williams) C. D. Adams, and Spermacoce alata Aubl., the current study...
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Truxillic and truxinic acid derivatives: configuration, source, and bioactivities of natural cyclobutane dimers
September 2020
Natural truxillic and truxinic acid derivatives are interesting cyclobutane dimers, with different stereo conformations formed by the orientation of groups on the cyclobutane. These derivatives are...
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Mitochondrial function: A new direction for the targeted treatment of cardiovascular diseases with Chinese herbal medicine
March 2025
Mitochondria play a central role in cardiovascular diseases, primarily by providing cellular energy and facilitating various cardiac functions. Excessive fat accumulation, circadian rhythm disturbances,...
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Study on the synergistic development of TCM service trade within the GBA
November 2023
This study analyzed the synergistic development of the Traditional Chinese Medicine (TCM) service trade within the Greater Bay Area (GBA) in China, aiming to provide suggestions and references for the...
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Peptide drugs application in metabolic diseases and discovery strategies
March 2022
Peptides (or polypeptides) are generally defined as those molecules compounded with less than 100 amino acids linked by peptide bonds, and the relative molecular weight is less than 10 000 Da usually....
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Visual analysis of drug research and development based on artificial intelligence
December 2024
The iteration of artificial intelligence (AI) technology provides new opportunities for drug research and experimental development. In recent years, AI-based drug research has continuously made new...
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Kalanchoe crenata decoction and infusion improve insulin resistance and fasting glycemia of diabetic obese rats MACAPOS 2
March 2025
Kalanchoe crenata is a medicinal plant traditionally used in diabetes management. Type 2 diabetes is a metabolic disorder characterized by abnormally high glycemia and insulin resistance. We investigated...
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A review on the pharmacological effects of Alpinia offiinarum Hance and its active ingredients
March 2025
Alpinia officinarum Hance (A. officinarum), as an important interior-warming herb in traditional Chinese medicine, is used to warm interior and disperse cold, regulate Qi and relieve pain. Modern research...
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Oral pH-triggered colon-specific ketoprofen loaded microspheres for the better management of early morning symptoms associated with rheumatoid arthritis. Part II: Pharmacokinetic and pharmacodynamic assessment in rats
March 2025
To evaluate the effectiveness of oral pH-triggered colon-specific ketoprofen-loaded microspheres (C-SKLMs) in managing early morning symptoms of rheumatoid arthritis (RA) through pharmacokinetic and...
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Research progress in application of alginate gel as tumor drug delivery carrier, for tumor localization and 3D tumor cell model
September 2024
As one of the hot materials in biomedical research, alginate gel shows great potential in tumor therapy with its unique physical and chemical properties. In order to better meet the complex needs of...
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Economic evaluation of isosorbide mononitrate sustained-release capsules for the treatment of angina pectoris
March 2024
Systematically evaluate the efficacy of (1) isosorbide mononitrate sustained-release capsules combined with conventional therapy and (2) conventional therapy alone in the treatment of angina pectoris...
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