Research progress on the application of Pleuropterus multiflorus in the treatment of androgenetic alopecia
December 2025
Androgenetic alopecia (AGA) is the most common form of hair loss, affecting approximately 21.3% of men and 6% of women in China, with an increasing trend among younger individuals. Currently, finasteride...
Study on the application of Aloe vera in cosmetology and clinical treatment of skin diseases
December 2024
The medicinal value of Aloe vera (AV) has been continuously explored and utilized in recent years, becoming a research hotspot. Some basic studies have found that AV had cosmetic effects such as whitening,...
Vitamins strategies for psoriasis: An update on current scientific evidence
December 2023
Psoriasis is an aggressive chronic skin disorder that requires various therapies such as topical, oral, and occasionally, subcutaneous, or intravenous. In contrast, vitamins have more significant evidence...
Exploring synergistic effects of bioactive compounds and pharmaceuticals in therapeutic applications
March 2026
Synergy arises when the combined effect of multiple agents exceeds the sum of their individual activities. Pharmacological and bioactive chemical synergy offers a promising approach to enhance therapeutic...
The transformative power of artificial intelligence in pharmaceutical manufacturing: Enhancing efficiency, product quality, and safety
June 2025
The pharmaceutical manufacturing industry transforms through artificial intelligence (AI) by implementing process improvements along with productivity enhancements and product quality improvements....
Deciphering the anti-senescence immune paradigm: Kidney yin-yang equilibrium in traditional Chinese medicine
June 2024
In traditional Chinese medicine (TCM), the kidney is considered the "innate foundation", and the abundance or diminution of its essence directly affects the growth, development, physical form, and physiological...
Design and optimization of polyherbal tablets for anti-inflammatory therapy: A design of experiment approach with in vitro and in vivo evaluation
March 2026
To develop and optimize polyherbal tablets containing Terminalia chebula, Moringa oleifera, and Ocimum sanctum as a multi-targeted therapeutic approach for the management of chronic inflammatory di...
Gut–brain axis in neurological disorders: mechanistic links and regulatory role of Chinese herbal medicines
March 2026
The gut–brain axis (GBA) is a bidirectional communication network integrating neural, immune, endocrine, and metabolic pathways that link the gastrointestinal tract and the central nervous system. Increasing...
Machine learning models for predicting pharmacokinetics and pharmacodynamics: A step toward personalized dosing
March 2026
Machine learning (ML) has become increasingly integrated within pharmacokinetics (PK) and pharmacodynamics (PD) modeling in recent years, and represents a new paradigm in precision medicine, enabling...
Recent advances in artificial intelligence for melanoma: A review of history, models, datasets, applications, and ethical and legal considerations
March 2026
Melanoma is one of the most lethal and aggressive forms of skin cancer, often presenting as evolving pigmented lesions. This review aims to examine melanoma from a holistic perspective by evaluating...
Traditional uses, chemical composition and pharmacological properties of genus Crotalaria
March 2026
The plants of genus Crotalaria are widely employed in traditional folk medicine to address various ailments. Extracts from these plants have been reported to exhibit diverse pharmacological properties,...
Review on clinical diagnosis, pathogenesis and therapeutic strategies of drug-induced liver injury
September 2025
Drug-induced liver injury (DILI) is a severe adverse reaction caused by various drugs and their metabolites, with complex clinical manifestations, and severe cases may progress to acute liver failure...
Therapeutic approaches to dyslipidaemia in Unani medicine: a narrative review
March 2026
Dyslipidaemia is one of the most common metabolic disorders, strongly linked with cardiovascular disease, obesity, and other components of metabolic syndrome. In Unani medicine, this condition is understood...
From traditional herb to modern therapeutics: phytochemistry, pharmacology, toxicology, and clinical translation challenges of Cyperus rotundus L
March 2026
Cyperus rotundus L. (C. rotundus.), widely distributed in tropical and temperate regions, is a perennial herb with a long history of application in traditional medical systems for treating emotional...
WRKY-mediated regulation of secondary metabolite production in medicinal plants
June 2026
WRKY transcription factors represent a quintessential regulatory clade involved in plant growth, stress adaptation, and secondary metabolic processes. Extensive research has elucidated that WRKY proteins...
Ethnobotanical survey and evaluation of antioxidant and angiotensin-converting enzyme inhibitory activities of selected medicinal plants
June 2026
The pathophysiology of several diseases, including hypertension, is linked to oxidative stress. Natural antioxidants play a crucial role in maintaining the balance between pro- and antioxidant levels....
Study on the potential medical beauty efficacy screening of acetyl hexapeptide-8 and the mechanism of regulating collagen regeneration
March 2026
Acetyl hexapeptide-8 (AH-8) is a synthetic polypeptide that can promote collagen regeneration; however, the underlying mechanism of this promoting effect and other potential medical beauty efficacy...
Phytochemical profiles, biological activities and medicinal importance of Aloe vera L.: A review
September 2025
Aloe vera (Av) is revered in Ayurveda as the "wand of heaven" or "heaven's blessing" and precisely the "silent healer". This herbaceous plant belongs to Asphodelaceae family, previously classified as...
Cancer-induced bone pain: spinal cord mechanisms and traditional Chinese medicine treatment
December 2021
Cancer-induced bone pain (CIBP) is a severe, intolerable, and complex pain condition caused by the primary bone tumor or bone metastasis. CIBP is a combination of complex pain states such as persistent...
Review on application and development of pharmacogenomics of adverse drug reactions
March 2025
Adverse drug reactions (ADRs) are a significant public health issue, contributing substantially to patient morbidity and mortality. The growing accessibility of genomic technologies has greatly advanced...
A scoping review of five selected underutilized medicinal plants of Sri Lanka: Focusing on ethnobotany, phytochemistry and bioactivities, and evaluation of their potential for novel herbal product development
June 2025
Ageratum conyzoides L., Artocarpus gomezianus Wall. ex Trécul, Euphorbia hirta L., Plectranthus zeylanicus Benth., and Piper sarmentosum Roxb. have long been utilized in traditional medical practices,...
Gut–brain–immune crosstalk in drug-resistant epilepsy: mechanisms and therapeutic perspectives
June 2026
Epilepsy is one of the most prevalent neurological disorders worldwide, affecting approximately 50–52 million individuals. Approximately 30% of patients develop drug-resistant epilepsy (DRE) despite...
Formulation and evaluation of carbamazepine loaded ethosomal nasal in-situ gel for brain targeted drug delivery
March 2025
This study aimed to develop a novel intranasal drug delivery system for carbamazepine, an antiepileptic drug, to enhance its therapeutic efficacy through targeted and sustained delivery. The goal was...
Cannabidiol as a modulator of NLRP3 inflammasome: Mechanistic insights and therapeutic potential
June 2026
Dysregulated activation of the NLRP3 inflammasome is a central driver of chronic inflammatory, neurodegenerative, metabolic, and autoimmune diseases, contributing significantly to the global burden...
Antidiabetic activity of bioactive fractions from Momordica cymbalaria Fenzl ex Naudin leaves: In vitro, in silico and in vivo evaluation
March 2026
This study evaluated the antidiabetic activity of Momordica cymbalaria Fenzl ex Naudin (MC) leaf fractions, a traditionally used remedy in southern India, through comprehensive in vitro, in silico,...