Most Downloaded Articles

Open access

ISSN: 2950-5755

AI and stroke rehabilitation: The past, present and future

This article offers a comprehensive review of research progress in the field of artificial intelligence and stroke rehabilitation. It begins by exploring its historical development, which has progressed...

3D bioprinting for facial reconstruction: Advances and challenges

Facial reconstruction presents significant challenges due to the complexity of soft and hard tissue integration. Traditional surgical approaches, including autografts and alloplastic implants, often...

The global, regional, and national burden of oral disorders in 204 countries and territories, 1990–2021, and projections to 2050: A systematic analysis for the Global Burden of Disease Study 2021

Oral disorders are among the most prevalent health conditions globally. This study aimed to systematically analyze the global, regional, and national burden of oral disorders between 1990 and 2021,...

Regenerative medicine in plastic surgery: The role of stem cells and bioprinting

Regenerative medicine is revolutionizing plastic surgery, offering novel approaches to reconstructive and aesthetic challenges through the use of stem cells and bioprinting technologies. Stem cells,...

Applications and prospects of artificial intelligence in wound healing

Wound healing is a critical aspect of clinical treatment, particularly in the management of complex wounds, including burns, diabetic foot ulcers (DFU). In recent years, artificial intelligence (AI)...

Regenerative rehabilitation: Mechanisms, clinical applications, and translational challenges

Regenerative rehabilitation is an evolving discipline that strategically unites regenerative medicine with rehabilitation science to enhance functional recovery through synergistic biological and physical...

Enhanced healing of burn wounds by dressings with alginate: An updated systematic review and meta-analysis of randomized controlled trials

This systematic review and meta-analysis evaluates the effectiveness of alginate dressings for burn treatment....

Natural and synthetic biomaterials, structural matrices-based wound dressings: Key properties, material correlation, and adaptability

The skin, the largest and fastest regenerating organ in the body, acts as a protective barrier against environmental threats. However, due to constant exposure, it is susceptible to various injuries....

ICF: The endpoint of rehabilitation assessment?

The International Classification of Functioning, Disability and Health (ICF), developed by the World Health Organization, provides a biopsychosocial framework for describing health and health-related...

Epidemiological features and temporal trends of burns and their subtypes, 1990–2021: Findings from the Global Burden of Disease Study 2021

Burns present a significant clinical challenge and are a critical global public health concern. Existing studies primarily focus on specific countries or regions, resulting in a lack of comprehensive...

Skin microecology and skin barrier repair, wound healing and appendage regeneration

Skin is one of the barriers for organisms to resist the stimulation of the external environment. Hundreds of millions of microorganisms are implanted on the skin surface, and skin microorganisms are...

Adipose-derived regenerative cells (ADRCs) in regenerative medicine: Current advances and future directions

Adipose-derived regenerative cells (ADRCs) have emerged as a transformative tool in regenerative medicine, offering multifaceted therapeutic potential due to their accessibility, immunocompatibility,...

The quest for the perfect healing of human skin wounds: Promising models

Human skin is a compound organ performing essential functions in direct environmental contact. An orchestrated set of complex biological processes sustained by intricate molecular interactions leads...

Clinical application of Chambo tilapia fish skin xenograft for skin tissue regeneration: A case report in a partial-thickness burns pediatric patient

WHO reports that burns account for more than 180,000 deaths annually with the majority of cases coming from low and middle-income countries due to limited resources in the management of burns. Currently,...

The biology and molecular regulation of MeSCs in hair follicles and their therapeutic potential for hypopigmentation disorders

Melanocytes, which produce melanin, a natural pigment, arise from the neural crest during embryonic development. They reside primarily in the epidermis and hair follicles, where they are responsible...

Stem cell secretomes from surgical waste: A novel approach to cancer therapy – An in vitro study

Cancer remains the second leading cause of mortality in India. Conventional chemotherapy is often limited by drug resistance, toxicity to healthy tissues, and promotion of metastasis, emphasizing the...

Green synthesis of AgNPs catalyzing free radical polymerization as wound dressing with an anti-bacterial effect

The development of wound dressing materials remains a critical need, driven by the complexity of wound environments and the intricate nature of the healing process. One of the most common wound dressing...

Cerium-based materials in burn wound healing: Development, mechanism and outlook

Burn injuries are underestimated trauma in which moderate and severe burns are often associated with death. Early excision is the gold standard treatment for burn injuries to reduce the risk of infection,...

Umbilical cord mesenchymal stem cell exosomes combined with collagen sponges contribute to neovascularization and wound healing in exposed bone wounds

Unmanaged bone exposed wounds that don't receive proper treatment can potentially lead to additional complications. Human umbilical cord mesenchymal stem cell (HUC-MSC)-derived exosomes (EXO) have a...

Low temperatures promote the healing of skin micro-injuries by inhibiting IL1β

The human skin holds a remarkable ability to adapt to external temperature changes to maintain thermal regulation and tissue integrity. Current research indicates that exposure to appropriate low temperatures...

YOLOv7-PSA, an intelligent detection model, is designed for assessing the severity of skin burns

We have developed an intelligent burn severity detection model called YOLOv7-PSA based on deep learning techniques and verified its efficiency and accuracy in assessing the severity of burn injuries....

Antibiotic-loaded bone cement applied to treatment of refractory hand burn wounds: 7 cases report

Our research focuses on the utilization of antibiotic-loaded bone cement in combination with skin graft to effectively treat refractory hand burn wounds, which are often complicated by infection and...

Development and validation of the second-modified nutrition risk screening 2002 for burn patients

To develop the second-modified nutrition risk screening 2002 and evaluate its reliability and validity....

A feasible clinical pathway of severe pyoderma gangrenosum in burn centers based on three clinical cases

To establish a standardized clinical pathway for the management of severe pyoderma gangrenosum (PG) in burn centers by analyzing and integrating insights from three detailed case studies....

Methylation-enriched telomere length mediates the association between lead exposure and cognitive function in an aging population

This study investigated the mediating role of methylation-predicted telomere length (mTL) in the association between lead (Pb) exposure and cognitive decline among older adults, leveraging data from...

Stay Informed

Register your interest and receive email alerts tailored to your needs. Sign up below.