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ISSN: 2950-5755

Consensus guidelines on negative pressure wound therapy for wound repair (2025 version)

The 2017 version of the Expert Consensus on the Application of Negative Pressure Wound Therapy (NPWT) in Burn Surgery has long been a valuable clinical reference for practitioners in China. In recent...

Applications and prospects of artificial intelligence in wound healing

Wound healing is a critical aspect of clinical treatment, particularly in the management of complex wounds, including burns, diabetic foot ulcers (DFU). In recent years, artificial intelligence (AI)...

Vital pulp therapy: A three-year clinical case series on regenerative potential and adhesive restoration strategies

Vital pulp therapy (VPT) aims to preserve the vitality and regenerative potential of the dental pulp after carious or mechanical exposure. The introduction of hydraulic calcium silicate cements has...

AI and stroke rehabilitation: The past, present and future

This article offers a comprehensive review of research progress in the field of artificial intelligence and stroke rehabilitation. It begins by exploring its historical development, which has progressed...

The global, regional, and national burden of oral disorders in 204 countries and territories, 1990–2021, and projections to 2050: A systematic analysis for the Global Burden of Disease Study 2021

Oral disorders are among the most prevalent health conditions globally. This study aimed to systematically analyze the global, regional, and national burden of oral disorders between 1990 and 2021,...

The evolution and current situation of regulations of China’s stem cell industry

Stem cells and regenerative medicine represent one of the most revolutionary frontiers in life sciences, holding transformative potential for treating refractory diseases and improving public health....

Natural and synthetic biomaterials, structural matrices-based wound dressings: Key properties, material correlation, and adaptability

The skin, the largest and fastest regenerating organ in the body, acts as a protective barrier against environmental threats. However, due to constant exposure, it is susceptible to various injuries....

Consensus on the application of generative artificial intelligence in medical manuscript writing

Generative artificial intelligence (AI) has become integral to medical writing, offering significant benefits in linguistic refinement and efficiency, particularly for non-native English speakers. However,...

Regenerative rehabilitation: Mechanisms, clinical applications, and translational challenges

Regenerative rehabilitation is an evolving discipline that strategically unites regenerative medicine with rehabilitation science to enhance functional recovery through synergistic biological and physical...

ICF: The endpoint of rehabilitation assessment?

The International Classification of Functioning, Disability and Health (ICF), developed by the World Health Organization, provides a biopsychosocial framework for describing health and health-related...

Epidemiological features and temporal trends of burns and their subtypes, 1990–2021: Findings from the Global Burden of Disease Study 2021

Burns present a significant clinical challenge and are a critical global public health concern. Existing studies primarily focus on specific countries or regions, resulting in a lack of comprehensive...

Enhanced healing of burn wounds by dressings with alginate: An updated systematic review and meta-analysis of randomized controlled trials

This systematic review and meta-analysis evaluates the effectiveness of alginate dressings for burn treatment....

Regenerative medicine in plastic surgery: The role of stem cells and bioprinting

Regenerative medicine is revolutionizing plastic surgery, offering novel approaches to reconstructive and aesthetic challenges through the use of stem cells and bioprinting technologies. Stem cells,...

Adult stem cell therapy for skin wound healing: A translational perspective from bench to bedside

Complex wounds remain a substantial clinical burden, despite advances in surgical reconstruction and biomaterial-based therapies. Adult stem cell strategies for skin repair have attracted wide interest,...

Functionalized BLGFs/ODEX hydrogel scaffold incorporating Oreochromis lidole skin collagen for bone tissue regeneration

Bones provide support to the body and protect vital internal organs. Bones have the capacity to repair minor defects, but this ability is substantially impaired in large defects. Mineralization, which...

Challenges and opportunities for cardiac organoids: A comprehensive review

Cardiac organoids, as 3D self-organizing models derived from pluripotent stem cells, can mimic the microstructure, cellular heterogeneity, and key functions of the human heart, providing a revolutionary...

Advances in hypertrophic scar animal model research: A multidimensional analysis from traditional models to emerging technologies

Hypertrophic scar (HS) results from abnormal healing with excessive collagen and fibroblast activity, leading to cosmetic and functional problems and significantly impairing quality of life. Due to...

Chinese expert consensus on Super-tension-reduction suture (Extra-tension-reduction suture) for surgical wounds (version 2025)

Super-tension-reduction suture (STRS), also named extra-tension-reduction suture, refers to a suture technique maintaining the skin closed in a state of zero tension or even negative tension for a relatively...

Macroscopic complete safe surgical resection of a large plexiform neurofibroma of the back: Narrative literature review and case report

Neurofibromatosis type 1 (NF1) is one of the most prevalent genetic disorders in humans, with plexiform neurofibromas (PN) affecting approximately 30% of individuals diagnosed with NF1. Surgical resection...

Retrospective analysis of hyperselective neurectomy for upper limb spasticity under wide awake local anaesthesia no tourniquet (WALANT)

Upper-limb spasticity resulting from stroke, traumatic brain injury (TBI), or cerebral palsy (CP) causes deformity and functional impairment. Hyperselective neurectomy (HSN) reduces spasticity by partial...

Mechanical properties of hydrogel wound dressing in skin regeneration – a meta-analysis of in vivo studies

This study quantitatively evaluated how the mechanical properties of hydrogel wound dressings influence in vivo wound healing outcomes, including wound closure, granulation tissue formation, collagen...

NSAIDs in paediatric burn injury: Mechanistic insights and clinical implications for inflammation and wound healing

Burn injuries in children trigger a profound inflammatory response characterised by rapid release of damage-associated molecular patterns (DAMPs), cytokine elevation, neutrophil activation, and, in...

Clinical application of Chambo tilapia fish skin xenograft for skin tissue regeneration: A case report in a partial-thickness burns pediatric patient

WHO reports that burns account for more than 180,000 deaths annually with the majority of cases coming from low and middle-income countries due to limited resources in the management of burns. Currently,...

Associations between awake-state cerebral hemodynamic activity and sleep quality: A longitudinal fNIRS study in young adults and implications for rehabilitation

Poor sleep quality is a significant public health challenge, particularly among young adults, and can impede recovery and rehabilitation. However, there is a lack of objective, field-deployable neurophysiological...

The quest for the perfect healing of human skin wounds: Promising models

Human skin is a compound organ performing essential functions in direct environmental contact. An orchestrated set of complex biological processes sustained by intricate molecular interactions leads...

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