Consensus guidelines on negative pressure wound therapy for wound repair (2025 version)
March 2026
The 2017 version of the Expert Consensus on the Application of Negative Pressure Wound Therapy (NPWT) in Burn Surgery has long been a valuable clinical reference for practitioners in China. In recent...
Vital pulp therapy: A three-year clinical case series on regenerative potential and adhesive restoration strategies
June 2026
Vital pulp therapy (VPT) aims to preserve the vitality and regenerative potential of the dental pulp after carious or mechanical exposure. The introduction of hydraulic calcium silicate cements has...
AI and stroke rehabilitation: The past, present and future
December 2025
This article offers a comprehensive review of research progress in the field of artificial intelligence and stroke rehabilitation. It begins by exploring its historical development, which has progressed...
Applications and prospects of artificial intelligence in wound healing
December 2025
Wound healing is a critical aspect of clinical treatment, particularly in the management of complex wounds, including burns, diabetic foot ulcers (DFU). In recent years, artificial intelligence (AI)...
The global, regional, and national burden of oral disorders in 204 countries and territories, 1990–2021, and projections to 2050: A systematic analysis for the Global Burden of Disease Study 2021
August 2025
Oral disorders are among the most prevalent health conditions globally. This study aimed to systematically analyze the global, regional, and national burden of oral disorders between 1990 and 2021,...
Natural and synthetic biomaterials, structural matrices-based wound dressings: Key properties, material correlation, and adaptability
December 2025
The skin, the largest and fastest regenerating organ in the body, acts as a protective barrier against environmental threats. However, due to constant exposure, it is susceptible to various injuries....
Consensus on the application of generative artificial intelligence in medical manuscript writing
March 2026
Generative artificial intelligence (AI) has become integral to medical writing, offering significant benefits in linguistic refinement and efficiency, particularly for non-native English speakers. However,...
Adult stem cell therapy for skin wound healing: A translational perspective from bench to bedside
September 2026
Complex wounds remain a substantial clinical burden, despite advances in surgical reconstruction and biomaterial-based therapies. Adult stem cell strategies for skin repair have attracted wide interest,...
The evolution and current situation of regulations of China’s stem cell industry
June 2026
Stem cells and regenerative medicine represent one of the most revolutionary frontiers in life sciences, holding transformative potential for treating refractory diseases and improving public health....
Epidemiological features and temporal trends of burns and their subtypes, 1990–2021: Findings from the Global Burden of Disease Study 2021
April 2025
Burns present a significant clinical challenge and are a critical global public health concern. Existing studies primarily focus on specific countries or regions, resulting in a lack of comprehensive...
ICF: The endpoint of rehabilitation assessment?
August 2025
The International Classification of Functioning, Disability and Health (ICF), developed by the World Health Organization, provides a biopsychosocial framework for describing health and health-related...
Regenerative rehabilitation: Mechanisms, clinical applications, and translational challenges
December 2025
Regenerative rehabilitation is an evolving discipline that strategically unites regenerative medicine with rehabilitation science to enhance functional recovery through synergistic biological and physical...
Camptodactyly of the Hand: Contemporary Concepts, Treatment Strategies, and a Structured Narrative Review
Available online 24 September 2026
Camptodactyly is a nontraumatic flexion contracture of the proximal interphalangeal (PIP) joint that may occur as an isolated deformity or as part of a syndromic condition. Management is challenging...
Enhanced healing of burn wounds by dressings with alginate: An updated systematic review and meta-analysis of randomized controlled trials
April 2025
This systematic review and meta-analysis evaluates the effectiveness of alginate dressings for burn treatment....
Regenerative medicine in plastic surgery: The role of stem cells and bioprinting
April 2025
Regenerative medicine is revolutionizing plastic surgery, offering novel approaches to reconstructive and aesthetic challenges through the use of stem cells and bioprinting technologies. Stem cells,...
Macroscopic complete safe surgical resection of a large plexiform neurofibroma of the back： Narrative literature review and case report
Available online 11 July 2026
Neurofibromatosis type 1 (NF1) is one of the most prevalent genetic disorders in humans, with plexiform neurofibromas (PN) affecting approximately 30% of individuals diagnosed with NF1. Surgical resection...
Chinese expert consensus on Super-tension-reduction suture (Extra-tension-reduction suture) for surgical wounds (version 2025)
June 2026
Super-tension-reduction suture (STRS), also named extra-tension-reduction suture, refers to a suture technique maintaining the skin closed in a state of zero tension or even negative tension for a relatively...
Challenges and opportunities for cardiac organoids: A comprehensive review
March 2026
Cardiac organoids, as 3D self-organizing models derived from pluripotent stem cells, can mimic the microstructure, cellular heterogeneity, and key functions of the human heart, providing a revolutionary...
Advances in hypertrophic scar animal model research: A multidimensional analysis from traditional models to emerging technologies
March 2026
Hypertrophic scar (HS) results from abnormal healing with excessive collagen and fibroblast activity, leading to cosmetic and functional problems and significantly impairing quality of life. Due to...
NSAIDs in paediatric burn injury: Mechanistic insights and clinical implications for inflammation and wound healing
September 2026
Burn injuries in children trigger a profound inflammatory response characterised by rapid release of damage-associated molecular patterns (DAMPs), cytokine elevation, neutrophil activation, and, in...
Fibroblast phenotypic plasticity: molecular mechanisms, context-dependent regulation, and clinical translation challenges— A comprehensive review
September 2026
Over the past century, fibroblasts were long regarded as homogeneous, passive connective-tissue cells, with their remarkable functional diversity and phenotypic plasticity largely overlooked. The rapid...
Electrospun nanofiber scaffolds for myocardial repair: Mechanistic design, preclinical advances, and translational perspectives
Available online 22 July 2026
Myocardial infarction (MI) remains a leading cause of global mortality and is characterized by irreversible cardiomyocyte loss, electrical uncoupling, fibrotic remodeling, and progressive ventricular...
The biology and molecular regulation of MeSCs in hair follicles and their therapeutic potential for hypopigmentation disorders
January 2025
Melanocytes, which produce melanin, a natural pigment, arise from the neural crest during embryonic development. They reside primarily in the epidermis and hair follicles, where they are responsible...
The quest for the perfect healing of human skin wounds: Promising models
April 2025
Human skin is a compound organ performing essential functions in direct environmental contact. An orchestrated set of complex biological processes sustained by intricate molecular interactions leads...
Advanced functional biobased materials for stem cell-mediated regenerative therapy
Available online 24 July 2026
Understanding and overcoming the limitations of cell survival, immune-mediated rejection, unpredictable cell differentiation, and poor host integration through stem cell-mediated regenerative therapy...