Applications and prospects of artificial intelligence in wound healing
December 2025
Wound healing is a critical aspect of clinical treatment, particularly in the management of complex wounds, including burns, diabetic foot ulcers (DFU). In recent years, artificial intelligence (AI)...
AI and stroke rehabilitation: The past, present and future
December 2025
This article offers a comprehensive review of research progress in the field of artificial intelligence and stroke rehabilitation. It begins by exploring its historical development, which has progressed...
Vital pulp therapy: A three-year clinical case series on regenerative potential and adhesive restoration strategies
Available online 31 January 2026
Vital pulp therapy (VPT) aims to preserve the vitality and regenerative potential of the dental pulp following carious or mechanical exposure. The introduction of hydraulic calcium silicate cements...
The global, regional, and national burden of oral disorders in 204 countries and territories, 1990–2021, and projections to 2050: A systematic analysis for the Global Burden of Disease Study 2021
August 2025
Oral disorders are among the most prevalent health conditions globally. This study aimed to systematically analyze the global, regional, and national burden of oral disorders between 1990 and 2021,...
Consensus guidelines on negative pressure wound therapy for wound repair (2025 version)
March 2026
The 2017 version of the Expert Consensus on the Application of Negative Pressure Wound Therapy (NPWT) in Burn Surgery has long been a valuable clinical reference for practitioners in China. In recent...
Natural and synthetic biomaterials, structural matrices-based wound dressings: Key properties, material correlation, and adaptability
December 2025
The skin, the largest and fastest regenerating organ in the body, acts as a protective barrier against environmental threats. However, due to constant exposure, it is susceptible to various injuries....
Regenerative medicine in plastic surgery: The role of stem cells and bioprinting
April 2025
Regenerative medicine is revolutionizing plastic surgery, offering novel approaches to reconstructive and aesthetic challenges through the use of stem cells and bioprinting technologies. Stem cells,...
Challenges and opportunities for cardiac organoids: A comprehensive review
March 2026
Cardiac organoids, as 3D self-organizing models derived from pluripotent stem cells, can mimic the microstructure, cellular heterogeneity, and key functions of the human heart, providing a revolutionary...
ICF: The endpoint of rehabilitation assessment?
August 2025
The International Classification of Functioning, Disability and Health (ICF), developed by the World Health Organization, provides a biopsychosocial framework for describing health and health-related...
Consensus on the application of generative artificial intelligence in medical manuscript writing
March 2026
Generative artificial intelligence (AI) has become integral to medical writing, offering significant benefits in linguistic refinement and efficiency, particularly for non-native English speakers. However,...
Enhanced healing of burn wounds by dressings with alginate: An updated systematic review and meta-analysis of randomized controlled trials
April 2025
This systematic review and meta-analysis evaluates the effectiveness of alginate dressings for burn treatment....
The evolution and current situation of regulations of China’s stem cell industry
Available online 26 February 2026
Stem cells and regenerative medicine represent one of the most revolutionary frontiers in life sciences, holding transformative potential for treating refractory diseases and improving public health....
Epidemiological features and temporal trends of burns and their subtypes, 1990–2021: Findings from the Global Burden of Disease Study 2021
April 2025
Burns present a significant clinical challenge and are a critical global public health concern. Existing studies primarily focus on specific countries or regions, resulting in a lack of comprehensive...
3D bioprinting for facial reconstruction: Advances and challenges
August 2025
Facial reconstruction presents significant challenges due to the complexity of soft and hard tissue integration. Traditional surgical approaches, including autografts and alloplastic implants, often...
Regenerative rehabilitation: Mechanisms, clinical applications, and translational challenges
December 2025
Regenerative rehabilitation is an evolving discipline that strategically unites regenerative medicine with rehabilitation science to enhance functional recovery through synergistic biological and physical...
Adipose-derived regenerative cells (ADRCs) in regenerative medicine: Current advances and future directions
August 2025
Adipose-derived regenerative cells (ADRCs) have emerged as a transformative tool in regenerative medicine, offering multifaceted therapeutic potential due to their accessibility, immunocompatibility,...
Advances in hypertrophic scar animal model research: A multidimensional analysis from traditional models to emerging technologies
March 2026
Hypertrophic scar (HS) results from abnormal healing with excessive collagen and fibroblast activity, leading to cosmetic and functional problems and significantly impairing quality of life. Due to...
Skin microecology and skin barrier repair, wound healing and appendage regeneration
January 2025
Skin is one of the barriers for organisms to resist the stimulation of the external environment. Hundreds of millions of microorganisms are implanted on the skin surface, and skin microorganisms are...
The quest for the perfect healing of human skin wounds: Promising models
April 2025
Human skin is a compound organ performing essential functions in direct environmental contact. An orchestrated set of complex biological processes sustained by intricate molecular interactions leads...
Advancements in staging, grading and regenerative therapeutic approaches for osteoarthritis
March 2026
Osteoarthritis (OA) is a complex and heterogeneous degenerative joint disease, which demands a shift from generalized palliative care to precision medicine, necessitating accurate staging and grading...
Butane inhalation abuse: A bibliometric analysis (1954–2024)
March 2026
Rising global butane-related abuse necessitates urgent public health research....
Clinical application of Chambo tilapia fish skin xenograft for skin tissue regeneration: A case report in a partial-thickness burns pediatric patient
August 2025
WHO reports that burns account for more than 180,000 deaths annually with the majority of cases coming from low and middle-income countries due to limited resources in the management of burns. Currently,...
The biology and molecular regulation of MeSCs in hair follicles and their therapeutic potential for hypopigmentation disorders
January 2025
Melanocytes, which produce melanin, a natural pigment, arise from the neural crest during embryonic development. They reside primarily in the epidermis and hair follicles, where they are responsible...
Cerium-based materials in burn wound healing: Development, mechanism and outlook
August 2025
Burn injuries are underestimated trauma in which moderate and severe burns are often associated with death. Early excision is the gold standard treatment for burn injuries to reduce the risk of infection,...
Mechanical properties of hydrogel wound dressing in skin regeneration – a meta-analysis of in vivo studies
March 2026
This study quantitatively evaluated how the mechanical properties of hydrogel wound dressings influence in vivo wound healing outcomes, including wound closure, granulation tissue formation, collagen...