Accuracy of rest seat prepared by rigid constraint template for removable partial denture: An in vitro study
October 2025
To establish a design and fabrication method for a rigid constraint guiding template for preparing rest seats for removable partial dentures (RPDs) and to verify the feasibility and accuracy of template-guided...
Opportunities and challenges in wearable ultrasound for oral health
October 2025
•Oral health.•Wearable ultrasound.•Continuous monitoring....
Antimicrobial peptides in oral medicine: From mechanisms to clinical translation
October 2025
Oral diseases pose significant threats to global public health, while conventional antibiotic therapies face increasing challenges from bacterial resistance. Antimicrobial peptides (AMPs) have emerged...
A digital cone beam computed tomography scan-based approach to transfer the preoperative maxillomandibular relation for immediate complete-arch interim restoration fabrication
October 2025
Achieving an accurate and stable maxillomandibular relation registration immediately following complete-arch implant placement surgery for interim restoration fabrication remains a significant clinical...
Ethical issues and coping strategies for artificial intelligence in medical research
October 2025
With the rapid development of artificial intelligence (AI) technologies, their applications in medical research have become increasingly widespread. However, the extensive use of AI has also raised...
Quantum dot-engineered extracellular vesicles derived from human exfoliated deciduous teeth stem cells for the dynamic monitoring and synergistic therapy of ischemic stroke
October 2025
Ischemic stroke, marked by oxidative stress and neuroinflammation in the long-term injury process after reperfusion, remains a leading global cause of disability and mortality, urging the need for innovative...
Clinical evaluation of 3D-printed templates for accurate and safe mini-screw implantation
October 2025
To develop mini-screw templates using three-dimensional (3D) printing technology to prevent root damage during implantation, and to evaluate the accuracy and safety of the implantation process....
Oral and maxillofacial surgery in the digital age: Current practice and perspective
October 2025
•Systematically reviewing the development and application of digital technology in Oral and maxillofacial surgery.•Timely and informative.•Prospecting development and limitation of digital technology...
Wearable technologies for dental medicine: From flexible sensors to the metaverse
July 2025
•Revisits wearable mechanical and chemical sensors in stomatology.•Presents advancements in flexible electronics in dental care.•Discusses the metaverse's potential in translational dental research...
Emerging roles of apoptotic bodies in immune homeostasis and oral disease therapeutics
July 2025
Oral diseases represent a global health challenge, affecting billions worldwide and imposing substantial health and economic burdens while significantly compromising the quality of life for those affected....
Senescence and oral cancer: From mechanisms to therapeutic opportunities
July 2025
Cellular senescence, characterized by stable cell cycle arrest, plays a multifaceted role in the development of oral cancer, attracting growing attention for its influence on cancer progression and...
SHED aggregate derived exosomes-shuttled miR-222 promotes the angiogenic properties of periodontal ligament stem cells and enhances periodontal regeneration
July 2025
Periodontal ligament stem cells (PDLSCs) aggregate is still limited in clinical application due to a lack of angiogenesis. This study aimed to investigate the effects and underlying mechanism of exosomes...
Artificial intelligence unlocks the future of oral organoid research
July 2025
Oral organoids, emerging as a powerful method for modeling oral development and diseases, show potential in fundamental research and clinical applications. However, their translational application in...
Fabrication of nano-structured biphasic calcium phosphate bioceramics to promote bone regeneration
July 2025
In recent years, inorganic non-metallic bone graft materials have attracted growing attention in bone defect repair. Among these, biphasic calcium phosphate (BCP) bioceramics, consisting of hydroxyapatite...
Modeling the laser irradiation induced carbonate loss in dental enamel for dental caries prevention
July 2025
The substitution of carbonate ions with phosphate ions in dental enamel results in an acid-soluble mineral. Laser irradiation-induced carbonate loss in enamel has been correlated with a reduction in...
Bionic repair strategy for craniomaxillofacial bone tissue reconstruction
July 2025
The clinical need for repairing craniofacial bone defects is significant, as relying solely on autologous bone grafts presents challenges such as resource deficiency and non-reusability. This has led...
A perspective on the mechanical engineering of biomimetic periodontal ligament models for biomedical applications
April 2025
The periodontal ligament (PDL) is a vital component of the periodontal tissue in the oral cavity. Its intricate mechanical and bacterial environment contributes to the high global prevalence of periodontal...
Translating research evidence into dental practice
April 2025
Evidence-based dentistry relies on effectively translating research findings into dental practice to improve patient outcomes and population health. Translational research aims to bridge the gap between...
Analgesic hydrogel patches formed by glutamic acid derivative for the treatment of oral mucosal wound
April 2025
Oral mucosal ulcerative diseases are one of the most prevalent oral diseases, which often interfere with the eating and speech of the patient and severely reduce the life quality. Currently, the main...
Engineered oral bacteria in the treatment of oral squamous cell carcinoma
April 2025
•The development of OSCC is closely associated with oral bacteria.•Engineered oral bacteria hold significant potential for the treatment of OSCC.•The clinical translation of engineered oral bacteria...
Minimizing the ergonomic risks in the process of periodontal scaling and root planning: A narrative review
April 2025
Work–related musculoskeletal disorders (WMSDs) are a prevalent occupational health concern among periodontists, particularly affecting the neck, shoulder, and wrist due to the repetitive and static...
Cell membrane-coated berberine-dipotassium glycyrrhizinate nanomaterials for treating pulmonary infections following craniofacial surgery
April 2025
Methicillin-resistant Staphylococcus aureus (MRSA) is a common pathogen in local and pulmonary infections following craniofacial surgery, and antibiotic resistance can significantly hinder patient recovery....
Modulation of stem cells from apical papilla using direct current electric fields: A pathway toward translational dentin regeneration
April 2025
Dentin is produced by odontoblasts, which originate from mesenchymal cells in the dental papilla. Although numerous studies have explored the molecular switches involved in the differentiation of stem...