Diversity, Complexity, and Challenges of Viral Infectious Disease Data in the Big Data Era: A Comprehensive Review
March 2025
Viral infectious diseases, characterized by their intricate nature and wide-ranging diversity, pose substantial challenges in the domain of data management. The vast volume of data generated by these...
scPANDA: PAN-Blood Data Annotator with a 10-Million Single-Cell Atlas
March 2025
Recent advancements in single-cell RNA sequencing (scRNA-seq) have revolutionized the study of cellular heterogeneity, particularly within the hematological system. However, accurately annotating cell...
Formula-S: Situated Visualization for Traditional Chinese Medicine Formula Learning
March 2025
The study of medicine formulas is a core component of traditional Chinese medicine (TCM), yet traditional learning methods often lack interactivity and contextual understanding, making it challenging...
Biomedical Data in China: Policy, Accumulation, Platform Construction, and Applications
March 2025
Biomedical data is surging due to technological innovations and integration of multidisciplinary data, posing challenges to data management. This article summarizes the policies, data collection efforts,...
Evaluation and Regulation of Medical Artificial Intelligence Applications in China
March 2025
Amid the global wave of digital economy, China's medical artificial intelligence applications are rapidly advancing through technological innovation and policy support, while facing multifaceted evaluation...
Data Spaces in Medicine and Health: Technologies, Applications, and Challenges
March 2025
Data space, as an innovative data management and sharing model, is emerging in the medical and health sectors. This study expounds on the conceptual connotation of data space and delineates its key...
Enrichment Analysis and Deep Learning in Biomedical Ontology: Applications and Advancements
March 2025
Biomedical big data, characterized by its massive scale, multi-dimensionality, and heterogeneity, offers novel perspectives for disease research, elucidates biological principles, and simultaneously...
Medication Rules of Hub Herb Pairs for Insomnia and Mechanism of Action: Results of Data Mining, Network Pharmacology, and Molecular Docking
December 2024
To explore the medication rules of traditional Chinese medicine (TCM) and mechanism of action of hub herb pairs for treating insomnia....
A Novel Signature Combing Cuproptosis- and Ferroptosis-Related Genes in Nonalcoholic Fatty Liver Disease
December 2024
To identify cuproptosis- and ferroptosis-related genes involved in nonalcoholic fatty liver disease and to determine the diagnostic value of hub genes....
Duration of Hypothermia is Associated with Postoperative Complications in Patients Undergoing Gynecological Surgery: A Prospective Cohort Study
December 2024
To investigate the relationship between hypothermia duration and postoperative complications in patients undergoing gynecological surgery....
Predictive Value of Systemic Immune Inflammation Index, Aggregate Index of Systemic Inflammation, and Systemic Inflammation Response Index in Lower Extremity Deep Venous Thrombosis Following Severe Trauma
December 2024
Venous thromboembolism is a highly prevalent condition after polytrauma, and recognized as an important factor contributing to poor prognosis. The aim of this study was to investigate the risk factors...
Current Status and Future Suggestions for Innovative Drug Research and Development in China
December 2024
In recent years, with the policy reform of new drug review and approval, China has ushered in a surge of innovative drug development. Based on the Pharnexcloud database and the Pharmcube database, we...
End-of-Life Inpatient Palliative Care for Glioblastoma Multiforme: Lessons Learned from One Case
December 2024
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor with a poor prognosis and limited survival. Patients with GBM have a high demand for palliative care. In our present case,...
Value of Myocardial Strain in Monitoring Fluorouracil-Based Chemotherapy-Related Cardiac Dysfunction in Gastrointestinal Cancer Patients
December 2024
To investigate the predictive value of myocardial strain for cardiotoxicity associated with fluorouracil-based chemotherapies in gastrointestinal cancer patients....
Video Feedback Improves Anesthesia Residents’ Communication Skill and Performance on Showing Empathy During Preoperative Interviews
December 2024
To determine the impact of scenario-based lecture and personalized video feedback on anesthesia residents’ communication skills during preoperative visits....
Polypyrimidine Tract-Binding Protein Enhances Zika Virus Translation by Binding to the 5’UTR of Internal Ribosomal Entry Site
September 2024
To identify the 5’ untranslated region of Zika virus (ZIKV 5’UTR) RNA-binding proteins and to investigate the impact of the binding protein on the activity of internal ribosomal entry site (IRES) located...
UBE2C as an Immune-Related Biomarker for Breast Cancer: A Study Based on Multiple Databases
September 2024
To screen the target genes that are associated with survival of breast cancer (BRCA) and explore their prognostic values and immune correlations with BRCA using multiple databases.....
Anesthesia Management in Hereditary Pheochromocytoma and Paraganglioma: Updated Insights into Clinical Features and Perioperative Care
September 2024
Approximately 40% of pheochromocytoma and paraganglioma (PPGL) cases are familial, typically presenting earlier with more complex symptoms. This paper synthesizes literature and guidelines to inform...
Genetic Evidence for Causal Association Between Hypertension and Chronic Pain: A Bidirectional Two-Sample Mendelian Randomization Study
September 2024
The extent to which the association between hypertension and chronic pain in observational studies is either causally linked or influenced by other shared risk factors has not been substantially addressed....
Dissecting Causal Relationships Between Plasma Metabolites and Osteoporosis: A Bidirectional Mendelian Randomization Study
September 2024
To investigate the causal relationships between plasma metabolites and osteoporosis via Mendelian randomization (MR) analysis....
Linggui Zhugan Decoction Improves High Glucose-Induced Autophagy in Podocytes
September 2024
To explore the influence of Linggui Zhugan Decoction (LGZGD) on high glucose induced podocyte autophagy....
Vascular Calcification: Where is the Cure?
September 2024
With the progress of aging, the incidence of vascular calcification (VC) gradually increases, which is correlated with cardiovascular events and all-cause death, aggravating global clinical burden....
Alignment Techniques in Total Knee Arthroplasty: Where do We Stand Today?
September 2024
Achieving optimal alignment in total knee arthroplasty (TKA) is a critical factor in ensuring optimal outcomes and long-term implant survival. Traditionally, mechanical alignment has been favored to...
BILL Strategy: Points to Consider During the Performance and Interpretation of Critical Care Echocardiography
September 2024
The growing utilization of critical care echocardiography (CCE) by clinicians necessitates a meticulous review of clinical conditions in critically ill patients, both before and during the examination....