Impact of COVID-19 vaccines on liver function: A state of the art and challenges for healthcare providers
January 2024
COVID-19 vaccines have significantly reduced the virus's spread, but they may impact liver function. Although most individuals tolerate the vaccines well, rare cases of liver injury have been reported....
Liver lobes and cirrhosis: Diagnostic insights from lobar ratios
January 2025
Liver cirrhosis is the formation of abnormal nodular structure and fibrosis. Globally it accounts for 4 % of all deaths. Alcohol, viral hepatitis, and non-alcoholic fatty liver disease are the most...
Alcohol-associated liver disease: A review
April 2025
Alcohol-associated Liver Disease (ALD) is a collection of liver disorders caused by prolonged and excessive alcohol consumption, ranging from fatty liver alterations to fibrosis and cirrhosis. This...
Use of ‘Diarrhea Stool Card’ in acute diarrhea management in under 5 Years children in resource constraints country
April 2024
Antibiotics are often overused in the management of diarrhea, despite few indications. Lack of confidence regarding the causative organism and limited access to diagnostic facilities contribute to the...
Efficacy and Safety of BoozLiv™ as an add on therapy in patients with alcoholic liver disease: An open-label, randomized controlled trial
October 2024
Alcoholic Liver Disease (ALD) poses a significant global health threat, contributing to millions of deaths each year. Despite the well-established link between chronic alcohol consumption and liver...
Ilaprazole: Distinctive pharmacokinetic and pharmacodynamic properties among proton pump inhibitors
July 2025
Ilaprazole is a new proton pump inhibitor (PPI) that provides effective and sustained intragastric acid suppression. As PPIs are foundational medications in the treatment of acid-related disorders,...
Bacillus coagulans as a potent intervention for treating irritable bowel syndrome: A systematic review and meta-analysis of randomized control trials
January 2024
Irritable bowel syndrome (IBS) is the most common functional gastrointestinal tract disorder. Bacillus coagulans (BC) is a potent spore-forming probiotic that has been proposed as a potent supplement...
Effective non-surgical treatment of hemorrhoids with sclerosing foam and novel injection device
October 2024
To determine the effectiveness of a novel protocol to treat patients with hemorrhoidal disease....
Prevalence of peptic ulcer disease and its associated factors in Jeddah Saudi Arabia
January 2025
Peptic ulcer disease's (PUD) global significance, emphasizing its health burdens and associations with factors like Helicobacter pylori infection and lifestyle habits. The need for comprehensive approaches...
Chronic anal fissures treated with Unani formulation – A series of case reports
January 2024
Chronic anal fissure is recognized for its profound impact on quality of life and the propensity for treatment relapse, underscoring the need to explore safe and alternative clinical interventions....
Drug-induced liver injury: An overview and update
April 2023
Drug-induced liver injury (DILI) is a relatively rare but important adverse event for a variety of commonly used drugs, herbal and dietary supplements, illegal drugs and novel agents. The actual epidemiology...
Colorectal cancer spectrum: From subtypes and epidemiology to oncotherapies
April 2025
Colorectal cancer (CRC) has an incidence rate of 10 % and is the third most common cause of mortality worldwide, following breast and lung cancer. The clinical symptoms of CRC appear in the last phases...
Chat Generative Pre-Trained Transformer (ChatGPT) usage in healthcare
July 2023
In recent years, with the rapid development of deep learning, artificial intelligence (AI) has gradually become a powerful assistant for humans in various aspects. The maturity and advancement of natural...
Exploring the Effects of Reflexology on Gastrointestinal Symptoms in Type-2 Diabetic Patients: A Quasi-Experimental Study
Available online 18 July 2025
Type 2 diabetes is a growing global health concern, often leading to gastrointestinal complications that impact quality of life. Reflexology, a non-invasive therapy, may help alleviate these symptoms,...
Refractory gastroesophageal reflux disease (GERD): A clinical, endoscopic, and histopathological perspective –a single centre cross-sectional study
July 2024
Gastroesophageal reflux disease (GERD) manifests as the regurgitation of stomach contents into the esophagus, causing symptoms and potential complications. Proton Pump Inhibitors (PPIs) stand as the...
Identification of key genes and pathways in the following pancreatic ductal adenocarcinoma (PDAC) using integrated bioinformatics analysis
July 2025
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, and understanding its molecular mechanisms is critical for improving diagnosis and treatment. This study analyzed microarray datasets...
Systemic immune-inflammation index: Unveiling the diagnostic potential in ulcerative colitis through a comprehensive systematic review and meta-analysis
January 2025
Ulcerative colitis (UC) is a chronic inflammatory bowel disease with unpredictable colon and rectum inflammation episodes. Evaluating disease activity is essential for effective management. The systemic...
The complexity of mucosal damage in gastroesophageal airway reflux disease: A molecular perspective
January 2025
Gastroesophageal airway reflux disease (GARD) refers to a class of diseases in which the contents of the digestive system reflux into esophagus, the upper and lower airways, mouth, ear and nose et al.,...
The digestive system under microgravity environment: Changes, mechanisms and the prospects of the future
April 2025
In recent years, the space industry has continued to improve and develop, and human beings have been staying in space for longer periods while facing the challenges of microgravity to human life. The...
Comparison of pain between laparoscopic appendectomy vs open appendectomy in patients with acute appendicitis
January 2024
Pain is almost the main problem after surgery, effective pain management is crucial for recovery, since poorly managed pain can have detrimental effects on a patient's physical functioning, mental health,...
The Human-AI Frontier: An in-depth exploration of physicians' apprehension and Outlook Towards Artificial Intelligence in gastroenterology healthcare
October 2025
Recent advances in artificial intelligence (AI) have transformed healthcare, offering potential in diagnosis, treatment, and patient management in gastroenterology. Understanding physicians' attitudes...
When the gut Speaks: The hidden toll of irritable bowel syndrome on body and mind
July 2025
Irritable bowel syndrome (IBS) is a multifaceted gastrointestinal disorder that transcends the gut, affecting the physical, psychological, and social well-being of millions worldwide. Despite its prevalence,...
Celiac disease: A rare cause of cirrhotic portal hypertension - A case report
April 2024
Celiac disease, triggered by gluten, rarely manifests as cirrhotic portal hypertension. We present the case of a 35-year-old male with concurrent cirrhosis and celiac disease, highlighting their complex...
Prospects of clinical trials for novel therapeutic approaches in celiac disease
July 2025
Celiac disease (CD) is a chronic a multifactorial immune-mediated systemic inflammatory disease of the small intestine caused by genetic and environmental factors, elicited by the ingestion of dietary...