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ISSN: 2949-7523

A 0.035-inch labeled guidewire with a smaller measured diameter enables a minimal-dilation plastic stent-based endoscopic ultrasound–guided gallbladder drainage workflow: A two-case report

Endoscopic ultrasound–guided gallbladder drainage (EUS-GBD) is an established alternative for acute cholecystitis in patients unfit for surgery. While cautery-enhanced lumen-apposing metal stents can...

A case of primary squamous cell carcinoma of the liver diagnosed by endoscopic ultrasound-guided fine-needle aspiration

Primary hepatic squamous cell carcinoma (PHSCC) is extremely rare in clinical practice. This article reports on a 72-year-old patient who was diagnosed with liver space-occupying lesions. MRI showed...

CytoRich Red–Based Specimen Processing Is Associated with Improved Histologic Diagnostic Performance in EUS-Guided Tissue Acquisition for Pancreatic Tumors: A Retrospective Before-and-After Study

Conventional specimen processing during endoscopic ultrasound-guided tissue acquisition (EUS-TA) may reduce tissue available for histologic assessment when part of the specimen is allocated to rapid...

Long-term Efficacy of EUS-BD versus ERCP as initial biliary drainage for Malignant Distal Biliary Obstruction: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Current guidelines suggest endoscopic retrograde cholangiopancreatography (ERCP) with self-expandable metal stent (SEMS) placement as initial biliary drainage for malignant distal biliary obstruction...

MRCP Unmasks Caroli Syndrome Initially Misdiagnosed as Periportal Fibrosis in a Young Adult from low resource setting.

Caroli syndrome is a rare congenital disorder characterized by intrahepatic bile duct dilatation with associated congenital hepatic fibrosis. Periportal fibrosis is often attributed to schistosomiasis...

Goblet Cell Adenocarcinoma of the Appendix Presenting as Recurrent Intestinal Obstruction: A Case Report

Cap-assisted snare compression for an impacted omega-shaped metallic esophageal foreign body

•An omega-shaped metallic handle was impacted in the upper esophagus.•Cap-assisted snare compression enabled controlled endoscopic retrieval.•Snare tightening reduced width and aligned the foreign body...

Green endoscopy: Sustainable practices and implementation strategies for environmentally responsible gastrointestinal care

Healthcare contributes an estimated approximately 5% of global greenhouse gas emissions, with endoscopic procedures among significant contributors through high energy consumption, extensive single-use...

Transformation of myelodysplastic syndrome to acute myeloid leukemia with leukemic infiltration of the colon without visible change on endoscopy: A case report

Extramedullary leukemic involvement refers to the infiltration of leukemic cells into tissues or organs outside the bone marrow and peripheral blood and occurs in approximately 3-8% of adult patients...

Primary enterolith-induced small bowel obstruction in an elderly male without underlying intestinal pathology: A case report

Enteroliths are a rare cause of intestinal obstruction. When obstruction is caused by an enterolith, it is often associated with underlying intestinal anomalies, such as diverticula. Acute intestinal...

The association between sleep disorder and risk of early-onset colorectal cancer: A narrative review

Sleep patterns and circadian rhythms play pivotal roles in human health, and their disruption has been associated with various adverse outcomes. This comprehensive narrative review focuses on the early-onset...

Epidemiology and underlying aetiology of liver cirrhosis in Africa, with emphasis on hepatitis B: Systematic review and meta-analysis

Liver cirrhosis is increasingly prevalent globally. Sub-Saharan Africa (SSA) has the world's highest cirrhosis related morbidity and mortality. Liver cirrhosis is potentially preventable condition when...

Primary squamous cell carcinoma of pancreas in a patient with Kaposi sarcoma: A rare case report

Primary squamous cell carcinoma (SCC) of the pancreas is an exceptionally rare malignancy, accounting for a very small proportion of pancreatic neoplasms. Its diagnosis requires exclusion of metastatic...

Alterations in renal antioxidant and glycolytic enzymes associated with liver cirrhosis in rats and their modulation by biochemic tissue salts Natrum sulphuricum and Natrum phosphoricum

Liver cirrhosis (LC) is often caused by chronic alcohol consumption and acetaminophen use. LC can lead to acute kidney injury (AKI) and chronic kidney disease (CKD), significantly impacting quality...

Unravelling the unexpected: intestinal malrotation in adults- a retrospective observational study

Although congenital intestinal malrotation is typically diagnosed in infancy, it can occasionally present in adults, often with vague and persistent gastrointestinal symptoms. Due to its rarity and...

Epigastric tactile hypersensitivity as a bedside clinical marker for functional epigastric pain: A prospective multicenter diagnostic accuracy study

Functional dyspepsia is a common gut–brain interaction disorder. Identifying simple bedside markers that distinguish functional from organic epigastric pain remains a clinical challenge. This study...

Analysis of the discrepancy between endoscopic and CT-based assessments of gastroesophageal junction laxity

Endoscopic gastroesophageal junction laxity under retroflexed view is a validated anatomical surrogate for the hiatal long diameter and correlates with objective markers of gastroesophageal reflux disease...

Rethinking colorectal cancer prevention in Tanzania: High malignancy rates in colorectal polyps and health-system gaps revealed through colonoscopy data

Colorectal cancer (CRC) is an important public health concern in sub-Saharan Africa; however, screening programs in many low-resource settings remain limited. Findings from colonoscopy-detected colorectal...

Toothpick-Induced Pancreatitis: Case Report, Review of Literature, and Proposed Management Approach

Most ingested foreign bodies are expelled naturally without complications. However, serious concerns such as obstruction, bleeding, and perforation can occur. Sharp foreign objects like toothpicks may...

Digital Twin Technology in Endoscopy: Current Applications, Challenges, and Future Perspectives

Endoscopic procedures have evolved significantly with advances in imaging, robotics, and artificial intelligence. However, procedural complexity, anatomical variations, and the high cost of device testing...

Factors affecting adherence to surveillance colonoscopies after resection of stage I to III colorectal cancer

After surgical resection for colorectal cancer (CRC), there is a 20-30% recurrence risk within the first 5 years for stage II and III patients. The National Comprehensive Cancer Network (NCCN) recommends...

Dietary Glutamate and Mismatch Repair Integrity: Interpreting Emerging Experimental Signals

Effect of laparoscopic W-H versus Nissen-Rossetti fundoplication for proton pump inhibitor dependent gastroesophageal reflux disease: A multicenter randomized controlled trial protocol

Our previous data showed that the W-H fundoplication had a similar mid-term satisfaction rate and a lower mid-term dysphagia rate compared with the Nissen-Rossetti fundoplication. But the results are...

Monosodium glutamate-induced alterations in MMR protein expression: A potential mechanism linking diet and colorectal cancer

Defective mismatch repair (MMR) proteins activate the microsatellite instability (MSI) pathway, contributing to colon carcinogenesis. Monosodium glutamate (MSG), a widely used flavor enhancer, has been...

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